未登录 IOLite: phase 1b trial of doublet/triplet combinations of dostarlimab with niraparib, carboplatin-paclitaxel, with or without bevacizumab in patients with advanced cancer Yap, Timothy A.; Bessudo, Alberto; Hamilton, Erika; Sachdev, Jasgit; Patel, Manish R.; Rodon, Jordi; Evilevitch, Lena; Duncan, Meghan; Guo, Wei; Kumar, Sujatha; Lu, Sharon; Dezube, Bruce J.; Gabrail, Nashat 分享 收藏
CLINICAL OUTCOMES OF OVARIAN CANCER PATIENTS TREATED WITH ALKS 4230, A NOVEL ENGINEERED CYTOKINE, IN COMBINATION WITH PEMBROLIZUMAB: ARTISTRY-1 TRIAL Winer, Ira; Gilbert, Lucy; Vaishampayan, Ulka; Rosen, Seth; Hoimes, Christopher; Muzaffar, Jameel; Spreafico, Anna; McDermott, David; Chu, Quincy; Dumas, Olivier; Chauhan, Aman; Chaudhry, Arvind; Tomczak, Piotr; Boni, Valentina; Bruno, Debora; Curtis, Kelly; Wang, Yan; Dorn, Elizabeth; Rege, Jessicca; Du, Yangchun; Bidollari, Ilda; Sun, Lei; Putiri, Emily; Losey, Heather; Dezube, Bruce; Ernstoff, Marc; Velcheti, Vamsidhar; Strauss, James 分享 收藏
PHASE 1/2 STUDY OF SUBCUTANEOUSLY ADMINISTERED ALKS 4230, A NOVEL ENGINEERED CYTOKINE, AS MONOTHERAPY AND IN COMBINATION WITH PEMBROLIZUMAB, IN PATIENTS WITH ADVANCED SOLID TUMORS: ARTISTRY-2 Powderly, John; Carthon, Bradley; Ernstoff, Marc; Olszanski, Anthony; Wrangle, John; Shields, Anthony; Piha-Paul, Sarina; Curtis, Kelly; Bidollari, Ilda; Du, Yangchun; Sun, Lei; Putiri, Emily; Wang, Yan; Losey, Heather; Dezube, Bruce; Dezube, Bruce; Vaishampayan, Ulka 分享 收藏
ALKS 4230 monotherapy and in combination with pembrolizumab (pembro) in patients (pts) with refractory solid tumours (ARTISTRY-1) Vaishampayan, U. N.; Muzaffar, J.; Velcheti, V.; Winer, I.; Hoimes, C. J.; Rosen, S. D.; Spreafico, A.; McDermott, D. F.; Chu, Q. S-C.; Dumas, O.; Gilbert, L.; Hirte, H.; Curtis, K. K.; Du, Y.; Bidollari, I.; Sun, L.; Putiri, E.; Losey, H. C.; Dezube, B.; Ernstoff, M. S. 分享 收藏
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer (vol 11, pg 1459, 2020) Farkkila, Anniina; Gulhan, Doga C.; Casado, Julia; Jacobson, Connor A.; Huy Nguyen; Kochupurakkal, Bose; Maliga, Zoltan; Yapp, Clarence; Chen, Yu-An; Schapiro, Denis; Zhou, Yinghui; Graham, Julie R.; Dezube, Bruce J.; Munster, Pamela; Santagata, Sandro; Garcia, Elizabeth; Rodig, Scott; Lako, Ana; Chowdhury, Dipanjan; Shapiro, Geoffrey I.; Matulonis, Ursula A.; Park, Peter J.; Hautaniemi, Sampsa; Sorger, Peter K.; Swisher, Elizabeth M.; D'Andrea, Alan D.; Konstantinopoulos, Panagiotis A. 分享 收藏
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer 免疫基因组学分析可预测卵巢癌患者对PARP抑制剂与PD-1抑制剂联合治疗的疗效反应 Farkkila, Anniina; Gulhan, Doga C.; Casado, Julia; Jacobson, Connor A.; Nguyen, Huy; Kochupurakkal, Bose; Maliga, Zoltan; Yapp, Clarence; Chen, Yu-An; Schapiro, Denis; Zhou, Yinghui; Graham, Julie R.; Dezube, Bruce J.; Munster, Pamela; Santagata, Sandro; Garcia, Elizabeth; Rodig, Scott; Lako, Ana; Chowdhury, Dipanjan; Shapiro, Geoffrey, I; Matulonis, Ursula A.; Park, Peter J.; Hautaniemi, Sampsa; Sorger, Peter K.; Swisher, Elizabeth M.; D'Andrea, Alan D.; Konstantinopoulos, Panagiotis A. 分享 收藏
Association of the tumor-immune microenvironment with response to niraparib and pembrolizumab in relapsed, platinum-resistant ovarian cancer Farkkila, Anniina; Lin, Jia R.; Casado, Julia; Huy Nguyen; Zhou, Yinghui; Graham, Julie R.; Dezube, Bruce J.; Waggoner, Steven; Munster, Pamela; Fleming, Gini F.; Santagata, Sandro; Matulonis, Ursula A.; Sorger, Peter K.; Swisher, Elizabeth M.; D'Andrea, Alan D.; Konstantinopoulos, Panagiotis 分享 收藏
Durability of clinical benefit with niraparib plus pembrolizumab in patients with advanced triple-negative breast cancer beyond BRCA: (TOPACIO/Keynote-162) Vinayak, S.; Tolaney, S. M.; Schwartzberg, L.; Mita, M.; McCann, G.; Tan, A. R.; Hendrickson, A. Wahner; Forero, A.; Anders, C.; Wulf, G.; Dillon, P.; Lynce, F.; Zarwan, C.; Erban, J.; Farkkila, A.; Zhou, Y.; Buerstatte, N.; Graham, J. R.; Arora, S.; Dezube, B.; Telli, M. L. 分享 收藏
Phase Ib study of pevonedistat, a NEDD8-activating enzyme inhibitor, in combination with docetaxel, carboplatin and paclitaxel, or gemcitabine, in patients with advanced solid tumors Lockhart, A. Craig; Bauer, Todd M.; Aggarwal, Charu; Lee, Carrie B.; Harvey, R. Donald; Cohen, Roger B.; Sedarati, Farhad; Nip, Tsz Keung; Faessel, Helene; Dash, Ajeeta B.; Dezube, Bruce J.; Faller, Douglas V.; Dowlati, Afshin 分享 收藏
Expanded safety analysis of pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukemia and myelodysplastic syndromes Swords, R. T.; Watts, J.; Erba, H. P.; Altman, J. K.; Maris, M.; Anwer, F.; Hua, Z.; Stein, H.; Faessel, H.; Sedarati, F.; Dezube, B. J.; Giles, F. J.; Medeiros, B. C.; DeAngelo, D. J. 分享 收藏
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Phase I Study of the Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Advanced Solid Tumors Sarantopoulos, John; Shapiro, Geoffrey I.; Cohen, Roger B.; Clark, Jeffrey W.; Kauh, John S.; Weiss, Glen J.; Cleary, James M.; Mahalingam, Devalingam; Pickard, Michael D.; Faessel, Helene M.; Berger, Allison J.; Burke, Kristine; Mulligan, George; Dezube, Bruce J.; Harvey, R. Donald 分享 收藏
Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma Shah, Jatin J.; Jakubowiak, Andrzej J.; O'Connor, Owen A.; Orlowski, Robert Z.; Harvey, R. Donald; Smith, Mitchell R.; Lebovic, Daniel; Diefenbach, Catherine; Kelly, Kevin; Hua, Zhaowei; Berger, Allison J.; Mulligan, George; Faessel, Helene M.; Tirrell, Stephen; Dezube, Bruce J.; Lonial, Sagar 分享 收藏
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A phase 1/pharmacokinetic study of sunitinib in combination with highly active antiretroviral therapy in human immunodeficiency virus-positive patients with cancer: AIDS Malignancy Consortium trial AMC 061 Rudek, Michelle A.; Moore, Page C.; Mitsuyasu, Ronald T.; Dezube, Bruce J.; Aboulafia, David; Gerecitano, John; Sullivan, Ryan; Cianfrocca, Mary E.; Henry, David H.; Ratner, Lee; Haigentz, Missak, Jr.; Dowlati, Afshin; Little, Richard F.; Ivy, Susan Percy; Deeken, John F. 分享 收藏
A Phase I First-in-Human Trial of Bardoxolone Methyl in Patients with Advanced Solid Tumors and Lymphomas Hong, David S.; Kurzrock, Razelle; Supko, Jeffrey G.; He, Xiaoying; Naing, Aung; Wheler, Jennifer; Lawrence, Donald; Eder, Joseph Paul; Meyer, Colin J.; Ferguson, Deborah A.; Mier, James; Konopleva, Marina; Konoplev, Sergej; Andreeff, Michael; Kufe, Donald; Lazarus, Hillard; Shapiro, Geoffrey I.; Dezube, Bruce J. 分享 收藏
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Human Immunodeficiency Virus-Associated Primary Lung Cancer in the Era of Highly Active Antiretroviral Therapy: A Multi-Institutional Collaboration D'Jaen, Gabriela A.; Pantanowitz, Liron; Bower, Mark; Buskin, Susan; Neil, Nancy; Greco, Erin M.; Cooley, Timothy P.; Henry, David; Stem, Jonathan; Dezube, Bruce J.; Stebbing, Justin; Aboulafia, David M. 分享 收藏
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