未登录Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+T and natural killer cell-stimulating capacity for cancer immunotherapyANV419的发现和开发，一种具有有效CD8 T和自然杀伤细胞刺激能力的IL-2/anti-IL-2抗体融合蛋白，用于癌症免疫治疗
Murer, Patrizia; Brannetti, Barbara; Rondeau, Jean-Michel; Petersen, Laetitia; Egli, Nicole; Popp, Simone; Regnier, Catherine; Richter, Kirsten; Katopodis, Andreas; Huber, Christoph .png)
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收藏ANV600 is a potent, Cis-signaling, non-alpha IL-2 agonist which efficiently expands intratumoral stem-like CD8 T cellsMurer, Patrizia; Salazar, Ulisse; Egli, Nicole; Petersen, Laetitia; Neubert, Pia; Richter, Kirsten; Stocker, Christian; Rau, Alexander; Katopodis, Andreas; Huber, Christoph 分享 收藏 分享 收藏 分享 收藏 PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensingGavin, Amanda L.; Huang, Deli; Huber, Christoph; Martensson, Annica; Tardif, Virginie; Skog, Patrick D.; Blane, Tanya R.; Thinnes, Therese C.; Osborn, Kent; Chong, Hayley S.; Kargaran, Farnaz; Kimm, Phoebe; Zeitjian, Armen; Sielski, Rachel L.; Briggs, Megan; Schulz, Sebastian R.; Zarpellon, Alessandro; Cravatt, Benjamin; Pang, Ee Shan; Teijaro, John; de la Torre, Juan Carlos; O'Keeffe, Meredith; Hochrein, Hubertus; Damme, Markus; Teyton, Luc; Lawson, Brian R.; Nemazee, David 分享 收藏 A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles encoding shared tumor antigens for immunotherapy of malignant melanomaJabulowsky, Robert A.; Loquai, Carmen; Mitzel-Rink, Heidrun; Utikal, Jochen; Gebhardt, Christoffer; Hassel, Jessica C.; Kaufmann, Roland; Pinter, Andreas; Derhovanessian, Evelyna; Anft, Christine; Attig, Sebastian; Deubel, Alexandra; Diken, Mustafa; Gold, Maike; Guertler, Claudia; Haas, Heinrich; Heesen, Ludwig; Kemmer-Brueck, Alexandra; Kranz, Lena M.; Kuehlcke, Klaus; Kuhn, Andreas; Langguth, Peter; Luxemburger, Ulrich; Maurus, Daniel; Meng, Martin; Mueller, Felicitas; Rae, Richard; Sari, Fatih; Schreeb, Katharina; Schwarck-Kokarakis, Doreen; Stein, Malte; Jaeger, Dirk; Grabbe, Stephan; Kreiter, Sebastian; Huber, Christoph; Tuereci, Oezlem; Sahin, Ugur 分享 收藏 A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles for potent melanoma immunotherapyJabulowsky, Robert A.; Loquai, Carmen; Utikal, Jochen; Hassel, Jessica; Kaufmann, Roland; Derhovanessian, Evelyna; Diken, Mustafa; Kranz, Lena M.; Haas, Heinrich; Attig, Sebastian; Anft, Christine; Buck, Janina; Diekmann, Jan; Fritz, Daniel; 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P.; Winter, Hauke; Withington, Tara; Wolchok, Jedd D.; Xiao, Weihua; Zitvogel, Laurence; Zwierzina, Heinz; Marincola, Francesco M.; Gajewski, Thomas F.; Wigginton, Jon M.; Disis, Mary L. 分享 收藏 分享 收藏 FLT3 Ligand Enhances the Cancer Therapeutic Potency of Naked RNA VaccinesKreiter, Sebastian; Diken, Mustafa; Selmi, Abderraouf; Diekmann, Jan; Attig, Sebastian; Huesemann, Yves; Koslowski, Michael; Huber, Christoph; Tuereci, Oezlem; Sahin, Ugur 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
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