Hira Lal Goel - Publications, H-index & Citations

Hira Lal Goel

University of Massachusetts Chan Medical School

33H指数

157论文数

4.6K被引数

收录论文 42

发表时间

Inducing ferroptosis to impede metastasis by inhibiting the calcium channel TRPC6 通过抑制钙通道TRPC6诱导铁死亡以抑制转移

Cell Reports

IF6.9

2025-11-08

OAAI

Boris S. Dimitrov; Dimpi Mukhopadhyay; Hira Lal Goel; Emmet R. Karner; Christi A. Silva; Ayush Kumar; Cornelia Peterson; Mengdie Wang; Arthur M. Mercurio

Resistance to radiation enhances metastasis by altering RNA metabolism 辐射抗性通过改变RNA代谢增强转移

Science Advances

IF12.5

2025-10-17

PREAI

Ayush Kumar; Kensei Kishimoto; Hira L. Goel; Christi A. Silva; Rui Li; Brendan Pacheco; Lihua J. Zhu; William A. Flavahan; Arthur M. Mercurio

Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates

CELL CHEMICAL BIOLOGY

IF7.2

2024-12-01

PREAI

Wang, Mengdie; Prachyathipsakul, Theeraphop; Wisniewski, Christi A.; Xiong, Choua; Goel, Shivam; Goel, Hira Lal; Karner, Emmet R.; Mukhopadhyay, Dimpi; Gupta, Prachi; Majee, Aniket; Thayumanavan, S.; Mercurio, Arthur M.

Neuropilin-2-expressing breast cancer cells mitigate radiation-induced oxidative stress through nitric oxide signaling

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-10-01

OAAI

Kumar, Ayush; Goel, Hira Lal; Wisniewski, Christi A.; Wang, Tao; Geng, Yansong; Wang, Mengdie; Goel, Shivam; Hu, Kai; Li, Rui; Zhu, Lihua J.; Clark, Jennifer L.; Ferreira, Lindsay M.; Brehm, Michael A.; FitzGerald, Thomas J.; Mercurio, Arthur M.

A prospective study to evaluate the prognostic implications and molecular mechanism of SLC40A1 gene in primary acute myeloid leukemia 一项前瞻性研究，旨在评估SLC40A1基因在原发性急性髓系白血病中的预后意义及分子机制。

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Goel, H.; Tanwar, P.

YAP/TAZ-mediated regulation of laminin 332 is enabled by β 4 integrin repression of ZEB1 to promote ferroptosis resistance

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-04-01

OAAI

Goel, Hira Lal; Karner, Emmet R.; Kumar, Ayush; Mukhopadhyay, Dimpi; Goel, Shivam; Mercurio, Arthur M.

The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing

CELL REPORTS

IF6.9

2023-11-01

OAAI

Mukhopadhyay, Dimpi; Goel, Hira Lal; Xiong, Choua; Goel, Shivam; Kumar, Ayush; Li, Rui; Zhu, Lihua Julie; Clark, Jennifer L.; Brehm, Michael A.; Mercurio, Arthur M.

Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple- negative breast cancer

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-05-03

OAAI

Xu, Zhiwen; Goel, Hira Lal; Burkart, Christoph; Burman, Luke; Chong, Yeeting E.; Barber, Alison G.; Geng, Yanyan; Zhai, Liting; Wang, Mengdie; Kumar, Ayush; Menefee, Ann; Polizzi, Clara; Eide, Lisa; Rauch, Kaitlyn; Rahman, Justin; Hamel, Kristina; Fogassy, Zachary; Klopp-Savino, Sofia; Paz, Suzanne; Zhang, Mingjie; Cubitt, Andrea; Nangle, Leslie A.; Mercurio, Arthur M.

Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-05-03

PREAI

Wang, Mengdie; Wisniewski, Christi A.; Xiong, Choua; Chhoy, Peter; Goel, Hira Lal; Kumar, Ayush; Zhu, Lihua Julie; Li, Rui; St Louis, Pamela A.; Ferreira, Lindsay M.; Pakula, Hubert; Xu, Zhiwen; Loda, Massimo; Jiang, Zhong; Brehm, Michael A.; Mercurio, Arthur M.

O-linked α2,3 sialylation defines stem cell populations in breast cancer

SCIENCE ADVANCES

IF12.5

2022-01-07

OAAI

Walker, Melanie R.; Goel, Hira Lal; Mukhopadhyay, Dimpi; Chhoy, Peter; Karner, Emmet R.; Clark, Jennifer L.; Liu, Haibo; Li, Rui; Zhu, Julie Lihua; Chen, Shuhui; Mahal, Lara K.; Bensing, Barbara A.; Mercurio, Arthur M.

Differentiation of Cancer Stem Cells through Nanoparticle Surface Engineering 纳米粒子表面工程诱导肿瘤干细胞分化的研究

ACS NANO

IF16

2020-11-09

OAAI

Geng, Yingying; Amante, John J.; Goel, Hira L.; Zhang, Xianzhi; Walker, Melanie R.; Luther, David C.; Mercurio, Arthur M.; Rotello, Vincent M.

Domain-specific antibodies to Neuropilin 2 implicate VEGF-C and not Semaphorin 3F in breast cancer stem cell function

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Nangle, Leslie A.; Burman, Luke; Goel, Hira L.; Xu, Zhiwen; Hamel, Kristina; Bloom, Nathaniel; Mercurio, Arthur M.

Real-time imaging of integrin β4 dynamics using a reporter cell line generated by Crispr/Cas9 genome editing

JOURNAL OF CELL SCIENCE

IF3.6

2019-07-31

OAAI

Elaimy, Ameer L.; Wang, Mengdie; Sheel, Ankur; Brown, Caitlin W.; Walker, Melanie R.; Amante, John J.; Xue, Wen; Chan, Amanda; Baer, Christina E.; Goel, Hira Lal; Mercurio, Arthur M.

The VEGF receptor neuropilin 2 promotes homologous recombination by stimulating YAP/TAZ-mediated Rad51 expression

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-06-24

OAAI

Elaimy, Ameer L.; Amante, John J.; Zhu, Lihua Julie; Wang, Mengdie; Walmsley, Charlotte S.; FitzGerald, Thomas J.; Goel, Hira Lal; Mercurio, Arthur M.

αvβ3 Integrin Mediates Radioresistance of Prostate Cancer Cells through Regulation of Survivin

MOLECULAR CANCER RESEARCH

IF4.7

2019-02-01

OAAI

Wang, Tao; Huang, Jiayi; Vue, Mai; Alavian, Michael R.; Goel, Hira Lal; Altieri, Dario C.; Languino, Lucia R.; FitzGerald, Thomas J.

VEGF-neuropilin-2 signaling promotes stem-like traits in breast cancer cells by TAZ-mediated repression of the Rac GAP β2-chimaerin

SCIENCE SIGNALING

IF6.6

2018-05-01

OAAI

Elaimy, Ameer L.; Guru, Santosh; Chang, Cheng; Ou, Jianhong; Amante, John J.; Zhu, Lihua Julie; Goel, Hira Lal; Mercurio, Arthur M.

The α6β4 integrin promotes resistance to ferroptosis

JOURNAL OF CELL BIOLOGY

IF6.4

2017-09-28

152

OAAI

Brown, Caitlin W.; Amante, John J.; Goel, Hira Lal; Mercurio, Arthur M.

P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer

CELL REPORTS

IF6.9

2016-03-01

OAAI

Goel, Hira Lal; Pursell, Bryan; Shultz, Leonard D.; Greiner, Dale L.; Brekken, Rolf A.; Vander Kooi, Craig W.; Mercurio, Arthur M.

Tead and AP1 Coordinate Transcription and Motility

CELL REPORTS

IF6.9

2016-02-01

188

OAAI

Liu, Xiangfan; Li, Huapeng; Rajurkar, Mihir; Li, Qi; Cotton, Jennifer L.; Ou, Jianhong; Zhu, Lihua J.; Goel, Hira L.; Mercurio, Arthur M.; Park, Joo-Seop; Davis, Roger J.; Mao, Junhao

IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG

ONCOGENE

IF7.3

2015-05-18

OAAI

Samanta, S.; Sun, H.; Goel, H. L.; Pursell, B.; Chang, C.; Khan, A.; Greiner, D. L.; Cao, S.; Lim, E.; Shultz, L. D.; Mercurio, A. M.

研究方向