Philip Leder - Publications, H-index & Citations

Philip Leder

Harvard University

133H指数

472论文数

7.4W被引数

收录论文 66

发表时间

Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Martin, S; Leder, P

Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

103

OAAI

Ecsedy, JA; Michaelson, JS; Leder, P

Isolation of a murine homologue of the Drosophila neuralized gene, a gene required for axonemal integrity in spermatozoa and terminal maturation of the mammary gland

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Vollrath, B; Pudney, J; Asa, S; Leder, P; Fitzgerald, K

Mutation of the Murine Bloom's syndrome gene produces global genome destabilization

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Chester, Nicholas; Babbe, Holger; Pinkas, Jan; Manning, Charlene; Leder, Philip

Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Weiss, RS; Leder, P; Vaziri, C

The Bloom's syndrome helicase is critical for development and function of the αβ T-cell lineage

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Babbe, Holger; Chester, Nicholas; Leder, Philip; Reizis, Boris

A Network of Conserved Damage Survival Pathways Revealed by a Genomic RNAi Screen

PLOS GENETICS

IF3.7

2009-06-19

OAAI

Ravi, Dashnamoorthy; Wiles, Amy M.; Bhavani, Selvaraj; Ruan, Jianhua; Leder, Philip; Bishop, Alexander J. R.

Formin1 disruption confers oligodactylism and alters Bmp signaling

HUMAN MOLECULAR GENETICS

IF3.2

2009-04-20

OAAI

Zhou, Fen; Leder, Philip; Zuniga, Aimee; Dettenhofer, Markus

Genomic Instability Resulting from Blm Deficiency Compromises Development, Maintenance, and Function of the B Cell Lineage

JOURNAL OF IMMUNOLOGY

IF3.4

2009-01-01

OAAI

Babbe, Holger; McMenamin, Jennifer; Hobeika, Elias; Wang, Jing; Rodig, Scott J.; Reth, Michael; Leder, Philip

A Maternal-Zygotic Effect Gene, Zfp57, Maintains Both Maternal and Paternal Imprints

DEVELOPMENTAL CELL

IF8.7

2008-10-01

550

OAAI

Li, Xiajun; Ito, Mitsuteru; Zhou, Fen; Youngson, Neil; Zuo, Xiaopan; Leder, Philip; Ferguson-Smith, Anne C.

Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency

ONCOGENE

IF7.3

2007-10-22

PREAI

Leder, A.; McMenamin, J.; Zhou, F.; Moran, J. L.; Beier, D. R.; Leder, P.

A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2007-05-29

OAAI

Lu, Jianrong; Ruhf, Marie-Laure; Perrimon, Norbert; Leder, Philip

Mitochondriotoxic compounds for cancer therapy

ONCOGENE

IF7.3

2006-08-07

136

OAAI

Fantin, V. R.; Leder, P.

Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2

EXPERIMENTAL CELL RESEARCH

IF3.5

2006-04-01

PREAI

Zhou, F; Leder, P; Martin, SS

A bifunctional targeted peptide that blocks HER-2 tyrosine kinase and disables mitochondrial function in HER-2-positive carcinoma cells

CANCER RESEARCH

IF16.6

2005-08-01

OAAI

Fantin, VR; Berardi, MJ; Babbe, H; Michelman, MV; Manning, CM; Leder, P

ζ-/- Thalassemic mice are affected by two modifying loci and display unanticipated somatic recombination leading to inherited variation

HUMAN MOLECULAR GENETICS

IF3.2

2005-01-13

OAAI

Leder, A; McMenamin, J; Fontaine, K; Bishop, A; Leder, P

Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin

IMMUNITY

IF26.3

2004-07-01

224

PREAI

Shigematsu, H; Reizis, B; Iwasaki, H; Mizuno, S; Hu, D; Traver, D; Leder, P; Sakaguchi, N; Akashi, K

A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth

ONCOGENE

IF7.3

2004-04-05

PREAI

Martin, SS; Ridgeway, AG; Pinkas, J; Lu, Y; Reginato, MJ; Koh, EY; Michelman, M; Daley, GQ; Brugge, JS; Leder, P

F16, a mitochondriotoxic compound, triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell

CANCER RESEARCH

IF16.6

2004-01-16

PREAI

Fantin, VR; Leder, P

Chromosome instability and tumor predisposition inversely correlate with BLM protein levels 染色体不稳定性和肿瘤易感性与BLM蛋白水平呈负相关

DNA REPAIR

IF2.7

2003-12-01

PREAI

McDaniel, LD; Chester, N; Watson, M; Borowsky, AD; Leder, P; Schultz, RA

研究方向