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A Grant-Based Experiment to Train Clinical Investigators: The AACR/ASCO Methods in Clinical Cancer Research Workshop Von Hoff, Daniel D.; Clark, Gary M.; Coltman, Charles A.; Disis, Mary L.; Eckhardt, S. G.; Ellis, Lee M.; Foti, Margaret; Garrett-Mayer, Elizabeth; Gonen, Mithat; Hidalgo, Manuel; Hilsenbeck, Susan G.; Littlefield, John H.; LoRusso, Patricia M.; Lyerly, H. Kim; Meropol, Neal J.; Patel, Jyoti D.; Piantadosi, Steven; Post, Dean A.; Regan, Meredith M.; Shyr, Yu; Tempero, Margaret A.; Tepper, Joel E.; Von Roenn, Jamie; Weiner, Louis M.; Young, Donn C.; Vu, Nu V. 分享 收藏
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Inhibition of MERTK Promotes Suppression of Tumor Growth in BRAF Mutant and BRAF Wild-Type Melanoma Sinik, Lenka; Minson, Katherine A.; Tentler, John J.; Carrico, Jacqueline; Bagby, Stacey M.; Robinson, William A.; Kami, Rotem; Burstyn-Cohen, Tal; Eckhardt, S. Gail; Wang, Xiaodong; Frye, Stephen, V; Earp, H. Shelton; DeRyckere, Deborah; Graham, Douglas K. 分享 收藏
A PDK1 inhibitors that has antitumor activity in a vemurafenib resistant BRAF(V600E)::NRAS(G12V) melanoma PDX James, Brian P.; Lemos, Robert, Jr.; Bagby, Stacey; Robinson, Steven; Robinson, William; Tentler, John; Eckhardt, S. Gail; Kirkpatrick, D. Lynn; Powis, Garth 分享 收藏
Safety and early evidence of activity of a first-in-human phase I study of the novel cancer stem cell (CSC) targeting antibody OMP-52M51 (anti-Notch1) administered intravenously to patients with certain advanced solid tumors Patnaik, A.; LoRusso, P.; Munster, P.; Tolcher, A. W.; Davis, S. L.; Heymach, J.; Ferraroto, R.; Xu, L.; Kapoun, A. M.; Faoro, L.; Lewicki, J. A.; Dupont, J.; Eckhardt, S. G. 分享 收藏
MERTK receptor tyrosine kinase is a therapeutic target in melanoma Schlegel, Jennifer; Sambade, Maria J.; Sather, Susan; Moschos, Stergios J.; Tan, Aik-Choon; Winges, Amanda; DeRyckere, Deborah; Carson, Craig C.; Trenthath, Dimitri G.; Tentler, John J.; Eckhardt, S. Gail; Kuan, Pei-Fen; Hamilton, Ronald L.; Duncan, Lyn M.; Miller, C. Ryan; Nikolaishvili-Feinberg, Nana; Midkiff, Bentley R.; Liu, Jing; Zhang, Weihe; Yang, Chao; Wang, Xiaodong; Frye, Stephen V.; Earp, H. Shelton; Shields, Janie M.; Graham, Douglas K. 分享 收藏
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The farnesyl transferase inhibitor, tipifarnib, is a potent inhibitor of the MDR1 gene product, P-glycoprotein, and demonstrates significant cytotoxic synergism against human leukemia cell lines Medeiros, B. C.; Landau, H. J.; Morrow, M.; Lockerbie, R. O.; Pitts, T.; Eckhardt, S. G. 分享 收藏
A phase I and pharmacokinetic study of Col-3 (metastat), an oral tetracycline derivative with potent matrix metalloproteinase and antitumor properties Syed, S; Takimoto, C; Hidalgo, M; Rizzo, J; Kuhn, JG; Hammond, LA; Schwartz, G; Tolcher, A; Patnaik, A; Eckhardt, SG; Rowinsky, EK 分享 收藏
Phase I dose-finding and pharmacokinetic trial of irinotecan (CPT-11) administered every two weeks Rothenberg, ML; Kuhn, JG; Schaaf, LJ; Rodriguez, GI; Eckhardt, SG; Villalona-Calero, MA; Rinaldi, DA; Hammond, LA; Hodges, S; Sharma, A; Elfring, GL; Petit, RG; Locker, PK; Miller, LL; von Hoff, DD 分享 收藏
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Phase I trial of paclitaxel and gemcitabine administered every two weeks in patients with refractory solid tumors Rothenberg, ML; Sharma, A; Weiss, GR; Villalona-Calero, MA; Eckardt, JR; Aylesworth, C; Kraynak, MA; Rinaldi, DA; Rodriguez, GI; Burris, HA; Eckhardt, SG; Stephens, CD; Forral, K; Nicol, SJ; Von Hoff', DD 分享 收藏
Activity of pivaloyloxymethyl butyrate, a novel anticancer agent, on primary human tumor colony-forming units Siu, LL; Von Hoff, DD; Rephaeli, A; Izbicka, E; Cerna, C; Gomez, L; Rowinsky, EK; Eckhardt, SG 分享 收藏
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