未登录A multilineage screen identifies actionable synthetic lethal interactions in human cancers
Fong, Samson H.; Kuenzi, Brent M.; Mattson, Nicole M.; Lee, John; Sanchez, Kyle; Bojorquez-Gomez, Ana; Ford, Kyle; Munson, Brenton P.; Licon, Katherine; Bergendahl, Sarah; Shen, John Paul; Kreisberg, Jason F.; Mali, Prashant; Hager, Jeffrey H.; White, Michael A.; Ideker, Trey .png)
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收藏High-throughput combinatorial CRISPR-Cas9 gene knockout reveals most genetic interactions are context dependentShen, John Paul; Zhao, Dongxin; Munson, Brenton; Birmingham, Amanda; Sasik, Roman; Bojorquez-Gomez, Ana; Licon, Katherine; Klepper, Kristin; Beckett, Alex; Sanchez, Kyle Salinas; Mali, Prashant; Ideker, Trey 分享 收藏 Disruption of NSD1 in Head and Neck Cancer Promotes Favorable Chemotherapeutic Responses Linked to HypomethylationBui, Nam; Huang, Justin K.; Bojorquez-Gomez, Ana; Licon, Katherine; Sanchez, Kyle S.; Tang, Sean N.; Beckett, Alex N.; Wang, Tina; Zhang, Wei; Shen, John Paul; Kreisberg, Jason F.; Ideker, Trey 分享 收藏 A global transcriptional network connecting noncoding mutations to changes in tumor gene expressionZhang, Wei; Bojorquez-Gomez, Ana; Velez, Daniel Ortiz; Xu, Guorong; Sanchez, Kyle S.; Shen, John Paul; Chen, Kevin; Licon, Katherine; Melton, Collin; Olson, Katrina M.; Yu, Michael Ku; Huang, Justin K.; Carter, Hannah; Farley, Emma K.; Snyder, Michael; Fraley, Stephanie I.; Kreisberg, Jason F.; Ideker, Trey 分享 收藏 分享 收藏 分享 收藏 Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactionsShen, John Paul; Zhao, Dongxin; Sasik, Roman; Luebeck, Jens; Birmingham, Amanda; Bojorquez-Gomez, Ana; Licon, Katherine; Klepper, Kristin; Pekin, Daniel; Beckett, Alex N.; Sanchez, Kyle Salinas; Thomas, Alex; Kuo, Chih-Chung; Du, Dan; Roguev, Assen; Lewis, Nathan E.; Chang, Aaron N.; Kreisberg, Jason F.; Krogan, Nevan; Qi, Lei; Ideker, Trey; Mali, Prashant 分享 收藏 A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer TherapySrivas, Rohith; Shen, John Paul; Yang, Chih Cheng; Sun, Su Ming; Li, Jianfeng; Gross, Andrew M.; Jensen, James; Licon, Katherine; Bojorquez-Gomez, Ana; Klepper, Kristin; Huang, Justin; Pekin, Daniel; Xu, Jia L.; Yeerna, Huwate; Sivaganesh, Vignesh; Kollenstart, Leonie; van Attikum, Haico; Aza-Blanc, Pedro; Sobol, Robert W.; Ideker, Trey 分享 收藏 分享 收藏 RAD17 loss of function is synthetically lethal with the checkpoint kinase inhibitors AZD7762 or MK-1775Shen, John Paul; Srivas, Rohith; Bojorquez-Gomez, Ana; Licon, Katherine; Sivaganesh, Vignesh; Xu, Jia L.; Yeerna, Huwate; Gross, Andrew; Li, Jian Feng; Sobol, Robert; Ideker, Trey 分享 收藏 
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