Nikolaus Heveker - Publications, H-index & Citations

Nikolaus Heveker

universite de montreal

39H指数

121论文数

4.9K被引数

收录论文 46

发表时间

The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment

CELLS

IF5.2

2019-06-18

OAAI

Reynders, Nathan; Abboud, Dayana; Baragli, Alessandra; Noman, Muhammad Zaeem; Rogister, Bernard; Niclou, Simone P.; Heveker, Nikolaus; Janji, Bassam; Hanson, Julien; Szpakowska, Martyna; Chevigne, Andy

Biased antagonism of CXCR4 avoids antagonist tolerance

SCIENCE SIGNALING

IF6.6

2018-10-16

OAAI

Hitchinson, Ben; Eby, Jonathan M.; Gao, Xianlong; Guite-Vinet, Francois; Ziarek, Joshua J.; Abdelkarim, Hazem; Lee, Youngshim; Okamoto, Yukari; Shikano, Sojin; Majetschak, Matthias; Heveker, Nikolaus; Volkman, Brian F.; Tarasova, Nadya I.; Gaponenko, Vadim

Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice

MOLECULAR METABOLISM

IF6.6

2018-06-01

OAAI

Fougerat, Anne; Pan, Xuefang; Smutova, Victoria; Heveker, Nikolaus; Cairo, Christopher W.; Issad, Tarik; Larrivee, Bruno; Medin, Jeffrey A.; Pshezhetsky, Alexey V.

Structure-Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-04-02

PREAI

Sekiguchi, Haruka; Kuroyanagi, Tomoko; Rhainds, David; Kobayashi, Kazuya; Kobayashi, Yuka; Ohno, Hiroaki; Heveker, Nikolaus; Akaji, Kenichi; Fujii, Nobutaka; Oishi, Shinya

Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2018-03-23

OAAI

Szpakowska, Martyna; Nevins, Amanda M.; Meyrath, Max; Rhainds, David; D'huys, Thomas; Guite-Vinet, Francois; Dupuis, Nadine; Gauthier, Pierre-Arnaud; Counson, Manuel; Kleist, Andrew; St-Onge, Genevieve; Hanson, Julien; Schols, Dominique; Volkman, Brian F.; Heveker, Nikolaus; Chevigne, Andy

Ligand-specific conformational transitions and intracellular transport are required for atypical chemokine receptor 3-mediated chemokine scavenging

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-01-01

OAAI

Montpas, Nicolas; St-Onge, Genevieve; Nama, Nassr; Rhainds, David; Benredjem, Besma; Girard, Melanie; Hickson, Gilles; Pons, Veronique; Heveker, Nikolaus

Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation

SCIENCE SIGNALING

IF6.6

2017-03-21

OAAI

Ziarek, Joshua J.; Kleist, Andrew B.; London, Nir; Raveh, Barak; Montpas, Nicolas; Bonneterre, Julien; St-Onge, Genevieve; DiCosmo-Ponticello, Crystal J.; Koplinski, Chad A.; Roy, Ishan; Stephens, Bryan; Thelen, Sylvia; Veldkamp, Christopher T.; Coffman, Frederick D.; Cohen, Marion C.; Dwinell, Michael B.; Thelen, Marcus; Peterson, Francis C.; Heveker, Nikolaus; Volkman, Brian F.

Mutational Analysis of Atypical Chemokine Receptor 3 (ACKR3/CXCR7) Interaction with Its Chemokine Ligands CXCL11 and CXCL12

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-01-01

OAAI

Benredjem, Besma; Girard, Melanie; Rhainds, David; St-Onge, Genevieve; Heveker, Nikolaus

Structure-Activity Relationship and Signaling of New Chimeric CXCR4 Agonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2016-08-11

PREAI

Mona, Christine E.; Besserer-Offroy, Elie; Cabana, Jerome; Lefrancois, Marilou; Boulais, Philip E.; Lefebvre, Marie-Reine; Leduc, Richard; Lavigne, Pierre; Heveker, Nikolaus; Marsault, Eric; Escher, Emanuel

Development of Novel CXC Chemokine Receptor 7 (CXCR7) Ligands: Selectivity Switch from CXCR4 Antagonists with a Cyclic Pentapeptide Scaffold

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-06-18

OAAI

Oishi, Shinya; Kuroyanagi, Tomoko; Kubo, Tatsuhiko; Montpas, Nicolas; Yoshikawa, Yasushi; Misu, Ryosuke; Kobayashi, Yuka; Ohno, Hiroaki; Heveker, Nikolaus; Furuya, Toshio; Fujii, Nobutaka

The chemokine CXC4 and CC2 receptors form homo- and heterooligomers that can engage their signaling G-protein effectors and βarrestin

FASEB JOURNAL

IF4.2

2014-07-22

OAAI

Armando, Sylvain; Quoyer, Julie; Lukashova, Viktorya; Maiga, Arhamatoulaye; Percherancier, Yann; Heveker, Nikolaus; Pin, Jean-Philippe; Prezeau, Laurent; Bouvier, Michel

Positive Regulation of Insulin Signaling by Neuraminidase 1

DIABETES

IF7.5

2013-06-14

OAAI

Dridi, Larbi; Seyrantepe, Volkan; Fougerat, Anne; Pan, Xuefang; Bonneil, Eric; Thibault, Pierre; Moreau, Allain; Mitchell, Grant A.; Heveker, Nikolaus; Cairo, Christopher W.; Issad, Tarik; Hinek, Alexander; Pshezhetsky, Alexey V.

Structure-based ligand discovery for the protein-protein interface of chemokine receptor CXCR4

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-03-19

149

OAAI

Mysinger, Michael M.; Weiss, Dahlia R.; Ziarek, Joshua J.; Gravel, Stephanie; Doak, Allison K.; Karpiak, Joel; Heveker, Nikolaus; Shoichet, Brian K.; Volkman, Brian F.

Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-10-11

199

OAAI

Drury, Luke J.; Ziarek, Joshua J.; Gravel, Stephanie; Veldkamp, Christopher T.; Takekoshi, Tomonori; Hwang, Samuel T.; Heveker, Nikolaus; Volkman, Brian F.; Dwinell, Michael B.

Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and Gαi activation (vol 282, pg 5111, 2007)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-08-01

OAAI

Berchiche, Yamina A.; Chow, Ken Y.; Lagane, Bernard; Leduc, Martin; Percherancier, Yann; Fujii, Nobutaka; Tamamura, Hirokazu; Bachelerie, Francoise; Heveker, Nikolaus

Agonists for the Chemokine Receptor CXCR4 趋化因子受体CXCR4的激动剂

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2011-06-15

OAAI

Lefrancois, Marilou; Lefebvre, Marie-Reine; Saint-Onge, Genevieve; Boulais, Philip E.; Lamothe, Simon; Leduc, Richard; Lavigne, Pierre; Heveker, Nikolaus; Escher, Emanuel

Different Effects of the Different Natural CC Chemokine Receptor 2b Ligands on β-Arrestin Recruitment, Gαi Signaling, and Receptor Internalization

MOLECULAR PHARMACOLOGY

IF3

2011-03-01

PREAI

Berchiche, Yamina A.; Gravel, Stephanie; Pelletier, Marie-Eve; St-Onge, Genevieve; Heveker, Nikolaus

The Peptidomimetic CXCR4 Antagonist TC14012 Recruits β-Arrestin to CXCR7 ROLES OF RECEPTOR DOMAINS

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-12-01

OAAI

Gravel, Stephanie; Malouf, Camille; Boulais, Philip E.; Berchiche, Yamina A.; Oishi, Shinya; Fujii, Nobutaka; Leduc, Richard; Sinnett, Daniel; Heveker, Nikolaus

The activity of the HIV-1 IRES is stimulated by oxidative stress and controlled by a negative regulatory element

NUCLEIC ACIDS RESEARCH

IF13.1

2010-10-08

OAAI

Gendron, Karine; Ferbeyre, Gerardo; Heveker, Nikolaus; Brakier-Gingras, Lea

Photolabeling identifies transmembrane domain 4 of CXCR4 as a T140 binding site

BIOCHEMICAL PHARMACOLOGY

IF5.6

2009-12-01

PREAI

Boulais, Philip E.; Dulude, Dominic; Cabana, Jerome; Heveker, Nikolaus; Escher, Emanuel; Lavigne, Pierre; Leduc, Richard

研究方向