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收藏分享 收藏 Integrating binding affinity and tonic signaling enables a rational CAR design for augmented T cell function整合结合亲和力和滋补信号可以为增强的T细胞功能提供合理的CAR设计
Barden, Markus; Elsenbroich, Patrick Ronan; Haas, Vivian; Ertelt, Moritz; Pervan, Philip; Velas, Lukas; Gergely, Bence; Szoeor, Arpad; Harrer, Dennis Christoph; Bezler, Valerie; Holzinger, Astrid; Friis, Rasmus Ulslev Wegener; Vereb, Gyorgy; Schuetz, Gerhard J.; Schoeder, Clara T.; Hombach, Andreas A.; Abken, Hinrich 分享 收藏 Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion单体激动剂肽/MHCII复合物以自主方式激活T细胞Platzer, Rene; Hellmeier, Joschka; Gohring, Janett; Perez, Iago Doel; Schatzlmaier, Philipp; Bodner, Clara; Focke-Tejkl, Margarete; Schuetz, Gerhard J.; Sevcsik, Eva; Stockinger, Hannes; Brameshuber, Mario; Huppa, Johannes B. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 CAR and TCR form individual signaling synapses and do not cross-activate, however, can co-operate in T cell activationBarden, Markus; Holzinger, Astrid; Velas, Lukas; Mezosi-Csaplar, Marianna; Szoeor, Arpad; Vereb, Gyoergy; Schuetz, Gerhard J.; Hombach, Andreas A.; Abken, Hinrich 分享 收藏 Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate effluxLuethi, Dino; Maier, Julian; Rudin, Deborah; Szollosi, Daniel; Angenoorth, Thomas J. F.; Stankovic, Stevan; Schittmayer, Matthias; Burger, Isabella; Yang, Jae-Won; Jaentsch, Kathrin; Holy, Marion; Das, Anand Kant; Brameshuber, Mario; Camacho-Hernandez, Gisela Andrea; Casiraghi, Andrea; Newman, Amy Hauck; Kudlacek, Oliver; Birner-Gruenberger, Ruth; Stockner, Thomas; Schutz, Gerhard J.; Sitte, Harald H. 分享 收藏 分享 收藏 分享 收藏 Cathelicidin and PMB neutralize endotoxins by multifactorial mechanisms including LPS interaction and targeting of host cell membranesCathelicidin和PMB通过多种机制中和内毒素，包括LPS相互作用和靶向宿主细胞膜Schromm, Andra B.; Paulowski, Laura; Kaconis, Yani; Kopp, Franziska; Koistinen, Max; Donoghue, Annemarie; Keese, Susanne; Nehls, Christian; Wernecke, Julia; Garidel, Patrick; Sevcsik, Eva; Lohner, Karl; Sanchez-Gomez, Susana; Martinez-de-Tejada, Guillermo; Brandenburg, Klaus; Brameshuber, Mario; Schuetz, Gerhard J.; Andrae, Joerg; Gutsmann, Thomas 分享 收藏 分享 收藏 DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigensDNA折纸证明了单个pMHCs作为T细胞抗原的独特刺激能力Hellmeier, Joschka; Platzer, Rene; Eklund, Alexandra S.; Schlichthaerle, Thomas; Karner, Andreas; Motsch, Viktoria; Schneider, Magdalena C.; Kurz, Elke; Bamieh, Victor; Brameshuber, Mario; Preiner, Johannes; Jungmann, Ralf; Stockinger, Hannes; Schutz, Gerhard J.; Huppa, Johannes B.; Sevcsik, Eva 分享 收藏 Illuminating the norepinephrine transporter: fluorescent probes based on nisoxetine and talopramCamacho-Hernandez, Gisela Andrea; Casiraghi, Andrea; Rudin, Deborah; Luethi, Dino; Ku, Therese C.; Guthrie, Daryl A.; Straniero, Valentina; Valoti, Ermanno; Schutz, Gerhard J.; Sitte, Harald H.; Newman, Amy Hauck 分享 收藏 Functionalized Bead Assay to Measure Three-dimensional Traction Forces during T-cell ActivationAramesh, Morteza; Mergenthal, Simon; Issler, Marcel; Plochberger, Birgit; Weber, Florian; Qin, Xiao-Hua; Liska, Robert; Duda, Georg N.; Huppa, Johannes B.; Ries, Jonas; Schuetz, Gerhard J.; Klotzsch, Enrico 分享 收藏 分享 收藏 分享 收藏 Homo- and Heteroassociations Drive Activation of ErbB3Varadi, Timea; Schneider, Magdalena; Sevcsik, Eva; Kiesenhofer, Dominik; Baumgart, Florian; Batta, Gyula; Kovacs, Tamas; Platzer, Rene; Huppa, Johannes B.; Szollosi, Janos; Schuetz, Gerhard J.; Brameshuber, Mario; Nagy, Peter 分享 收藏 分享 收藏 
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