Matthew D. Shoulders - Publications, H-index & Citations

Matthew D. Shoulders

massachusetts institute of technology

30H指数

149论文数

6.8K被引数

收录论文 40

发表时间

Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network HSF1调控的蛋白质稳态网络增强的显性负性TP53突变

Molecular Cell

IF16.6

2026-01-14

PREAI

Stephanie Halim; Rebecca M. Sebastian; Kristi E. Liivak; Jessica E. Patrick; Tiffani Hui; David R. Amici; Andrew O. Giacomelli; Paulina Rios; Vincent L. Butty; William C. Hahn; Francisco J. Sánchez-Rivera; Marc L. Mendillo; Yu-Shan Lin; Matthew D. Shoulders

Failed Cellular Surveillance Enables Pathogenic Matrix Deposition in a COL2A1-Related Osteoarthritis 细胞监测功能失调导致COL2A1相关骨关节炎中病原性基质沉积

Journal of Biological Chemistry

IF3.9

2025-06-01

OAAI

Kathryn M. Yammine; Sophia Mirda Abularach; Michael Xiong; Seo-yeon Kim; Agata A. Bikovtseva; Vincent L. Butty; Richard P. Schiavoni; John F. Bateman; Shireen R. Lamandé; Matthew D. Shoulders

An outcome- defining role for the triple- helical domain in regulating collagen- I assembly 三螺旋结构域在调节胶原蛋白I组装中的结果定义作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-11-06

OAAI

Yammine, Kathryn M.; Li, Rasia C.; Borgula, Isabella M.; Abularach, Sophia Mirda; DiChiara, Andrew S.; Raines, Ronald T.; Shoulders, Matthew D.

Endoplasmic Reticulum Oxidative Stress Promotes Glutathione-Dependent Oxidation of Collagen-1A1 and Promotes Lung Fibroblast Activation

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IF5.3

2024-11-01

PREAI

Druso, Joseph E.; Macpherson, Maximilian B.; Chia, Shi B.; Elko, Evan; Aboushousha, Reem; Seward, David J.; Abdelhamid, Hend; Erickson, Cuixia; Corteselli, Elizabeth; Tarte, Megan; Peng, Zhihua; Bernier, Daniel; Zito, Ester; Shoulders, Matthew D.; Thannickal, Victor J.; Huang, Steven; van der Vliet, Albert; Anathy, Vikas; Janssen-Heininger, Yvonne M. W.

MutaT7GDE: A Single Chimera for the Targeted, Balanced, Efficient, and Processive Installation of All Possible Transition Mutations In Vivo

ACS SYNTHETIC BIOLOGY

IF3.9

2024-08-27

PREAI

Mengiste, Amanuella A.; McDonald, Julie L.; Tran, Minh Thuan Nguyen; Plank, Anna V.; Wilson, Robert H.; Butty, Vincent L.; Shoulders, Matthew D.

ER procollagen storage defect without coupled unfolded protein response drives precocious arthritis

LIFE SCIENCE ALLIANCE

IF2.9

2024-07-09

OAAI

Yammine, Kathryn M.; Abularach, Sophia Mirda; Kim, Seo-yeon; Bikovtseva, Agata A.; Lilianty, Jinia; Butty, Vincent L.; Schiavoni, Richard P.; Bateman, John F.; Lamande, Shireen R.; Shoulders, Matthew

Evolutionary druggability for low-dimensional fitness landscapes toward new metrics for antimicrobial applications 针对抗菌应用的新指标的低维适应性景观的进化可药物性

ELIFE

IF0

2024-06-04

OAAI

Guerrero, Rafael F.; Dorji, Tandin; Harris, Ra'Mal M.; Shoulders, Matthew D.; Ogbunugafor, C. Brandon

The immune-evasive proline-283 substitution in influenza nucleoprotein increases aggregation propensity without altering the native structure

SCIENCE ADVANCES

IF12.5

2024-04-19

OAAI

Yoon, Jimin; Zhang, Yu Meng; Her, Cheenou; Grant, Robert A.; Ponomarenko, Anna I.; Ackermann, Bryce E.; Hui, Tiffani; Lin, Yu-Shan; Debelouchina, Galia T.; Shoulders, Matthew D.

Expanded MutaT7 toolkit efficiently and simultaneously accesses all possible transition mutations in bacteria

NUCLEIC ACIDS RESEARCH

IF13.1

2023-01-30

OAAI

Mengiste, Amanuella A.; Wilson, Robert H.; Weissman, Rachel F.; Papa III, Louis J.; Hendel, Samuel J.; Moore, Christopher L.; Butty, Vincent L.; Shoulders, Matthew D.

Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis 热休克因子1的缺失促进肝星状细胞活化并驱动肝纤维化

HEPATOLOGY COMMUNICATIONS

IF4.6

2022-08-09

OAAI

Choudhury, Asmita; Ratna, Anuradha; Lim, Arlene; Sebastian, Rebecca M.; Moore, Christopher L.; Filliol, Aveline A.; Bledsoe, Jacob; Dai, Chengkai; Schwabe, Robert F.; Shoulders, Matthew D.; Mandrekar, Pranoti

Thermal Proteome Profiling Reveals the O-GlcNAc-Dependent Meltome

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-03-01

OAAI

King, Dustin T.; Serrano-Negron, Jesus E.; Zhu, Yanping; Moore, Christopher L.; Shoulders, Matthew D.; Foster, Leonard J.; Vocadlo, David J.

Directed evolution in mammalian cells 哺乳动物细胞的定向进化

NATURE METHODS

IF32.1

2021-04-07

OAAI

Hendel, Samuel J.; Shoulders, Matthew D.

Collagen's enigmatic, highly conserved N-glycan has an essential proteostatic function 胶原蛋白的神秘，高度保守的N-聚糖具有必不可少的蛋白抑制功能

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-05

OAAI

Li, Rasia C.; Wong, Madeline Y.; DiChiara, Andrew S.; Hosseini, Azade S.; Shoulders, Matthew D.

Elucidation of proteostasis defects caused by osteogenesis imperfecta mutations in the collagen-?2(I) C-propeptide domain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-07-01

OAAI

Ngoc-Duc Doan; Hosseini, Azade S.; Bikovtseva, Agata A.; Huang, Michelle S.; DiChiara, Andrew S.; Papa, Louis J., III; Koller, Antonius; Shoulders, Matthew D.

HSF1 Activation Can Restrict HIV Replication

ACS INFECTIOUS DISEASES

IF3.8

2020-06-05

OAAI

Nekongo, Emmanuel E.; Ponomarenko, Anna, I; Dewal, Mahender B.; Butty, Vincent L.; Browne, Edward P.; Shoulders, Matthew D.

Mutation-Dependent Capacity of the ER Proteostasis Network to Quality Control Disease-Causing Collagen Misfolding

FASEB JOURNAL

IF4.2

2020-04-19

PREAI

Bikovtseva, Agata; Ngoc-Duc Doan; DiChiara, Andrew; Del Rosario, Amanda; Shoulders, Matthew

Targeting defective proteostasis in the collagenopathies

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2019-06-01

OAAI

Wong, Madeline Y.; Shoulders, Matthew D.

SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock

CELL REPORTS

IF6.9

2019-01-01

OAAI

Liebelt, Frauke; Sebastian, Rebecca M.; Moore, Christopher L.; Mulder, Monique P. C.; Ovaa, Huib; Shoulders, Matthew D.; Vertegaal, Alfred C. O.

An Adaptable Platform for Directed Evolution in Human Cells

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2018-11-14

OAAI

Berman, Chet M.; Papa, Louis J., III; Hendel, Samuel J.; Moore, Christopher L.; Suen, Patreece H.; Weickhardt, Alexander F.; Doan, Ngoc-Duc; Kumar, Caiden M.; Uil, Taco G.; Butty, Vincent L.; Hoeben, Robert C.; Shoulders, Matthew D.

A cysteine-based molecular code informs collagen C-propeptide assembly

NATURE COMMUNICATIONS

IF15.7

2018-10-11

OAAI

DiChiara, Andrew S.; Li, Rasia C.; Suen, Patreece H.; Hosseini, Azade S.; Taylor, Rebecca J.; Weickhardt, Alexander F.; Malhotra, Diya; McCaslin, Darrell R.; Shoulders, Matthew D.

研究方向