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Robert V. Farese

University of Michigan

63H指数
281论文数
1.4W被引数
收录论文 56
发表时间
The Irs1 Branch of the Insulin Signaling Cascade Plays a Dominant Role in Hepatic Nutrient Homeostasis
err2023-03-21
err135
errOAAI
errGuo, Shaodong; Copps, Kyle D.; Dong, Xiaocheng; Park, Sunmin; Cheng, Zhiyong; Pocai, Alessandro; Rossetti, Luciano; Sajan, Mini; Farese, Robert V.; White, Morris F.
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Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin-resistant forms of obesity and type 2 diabetes mellitus
errMEDCOMM
IF10.7
err2021-02-25
err5
errOAAI
errSajan, Mini P.; Hansen, Barbara C.; Acevedo-Duncan, Mildred; Kindy, Mark S.; Cooper, Denise R.; Farese, Robert V.
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Atypical PKC controls β-secretase expression and thereby regulates production of Alzheimer plaque precursor Aβ in brain and insulin receptor degradation in liver非典型PKC控制 β-分泌酶的表达,从而调节大脑中阿尔茨海默氏斑块前体a β 的产生和肝脏中胰岛素受体的降解
err2020-03-01
err0
PREAI
errSajan, Mini P.; Braun, Ursula; Leitges, Michael; Park, Colin; Diamond, David M.; Wu, Jin; Hansen, Barbara C.; Duncan, Mildred Acevedo; Apostolatos, Christopher A.; Apostolatos, Andre H.; Kindy, Mark; Farese, Robert V.
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Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance
err2018-03-01
err30
PREAI
errSajan, Mini P.; Lee, Mackenzie C.; Foufelle, Fabienne; Sajan, Joshua; Cleland, Courtney; Farese, Robert V.
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Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced ObesityPOMC神经元中蛋白激酶C λ 的缺失易患饮食诱导的肥胖
err2017-01-10
err19
errOAAI
errDorfman, Mauricio D.; Krull, Jordan E.; Scarlett, Jarrad M.; Guyenet, Stephan J.; Sajan, Mini P.; Damian, Vincent; Nguyen, Hong T.; Leitges, Michael; Morton, Gregory J.; Farese, Robert V.; Schwartz, Michael W.; Thaler, Joshua P.
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Compensation for PKMζ in long-term potentiation and spatial long-term memory in mutant mice突变小鼠的长时程增强和空间长时程记忆中pkm ζ 的补偿
err2016-05-17
err143
errOAAI
errTsokas, Panayiotis; Hsieh, Changchi; Yao, Yudong; Lesburgueres, Edith; Wallace, Emma Jane Claire; Tcherepanov, Andrew; Jothianandan, Desingarao; Hartley, Benjamin Rush; Pan, Ling; Rivard, Bruno; Farese, Robert V.; Sajan, Mini P.; Bergold, Peter John; Hernandez, Alejandro Ivan; Cottrell, James E.; Shouval, Harel Z.; Fenton, Andre Antonio; Sacktor, Todd Charlton
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Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1-40/42 and Phospho-Tau May Abet Alzheimer Development
err2016-02-19
err76
errOAAI
errSajan, Mini; Hansen, Barbara; Ivey, Robert, III; Sajan, Joshua; Ari, Csilla; Song, Shijie; Braun, Ursula; Leitges, Michael; Farese-Higgs, Margaret; Farese, Robert V.
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Divergent Regulation of Hepatic Glucose and Lipid Metabolism by Phosphoinositide 3-Kinase via Akt and PKCλ/ζ (vol 3, pg 343, 2006)
err2016-02-01
err2
errOAAI
errTaniguchi, Cullen M.; Kondo, Tatsuya; Sajan, Mini; Luo, Ji; Bronson, Roderick; Asano, Tomoichiro; Farese, Robert; Cantley, Lewis C.; Kahn, C. Ronald
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Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C-i
err2012-04-01
err32
errOAAI
errSajan, Mini P.; Nimal, Sonali; Mastorides, Stephen; Acevedo-Duncan, Mildred; Kahn, C. Ronald; Fields, Alan P.; Braun, Ursula; Leitges, Michael; Farese, Robert V.
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Functional Genomic Analyses Identify Pathways Dysregulated by Progranulin Deficiency, Implicating Wnt Signaling
errNEURON
IF15
err2011-09-01
err121
errOAAI
errRosen, Ezra Y.; Wexler, Eric M.; Versano, Revital; Coppola, Giovanni; Gao, Fuying; Winden, Kellen D.; Oldham, Michael C.; Martens, Lauren Herl; Zhou, Ping; Farese, Robert V., Jr.; Geschwind, Daniel H.
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A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma (vol 43, pg 784, 2011)
err2011-09-01
err0
PREAI
errPillai, Prajit; Desai, Shraddha; Patel, Rekha; Sajan, Mini; Farese, Robert; Ostrov, David; Acevedo-Duncan, Mildred
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Suberoylanilide Hydroxamic Acid (Vorinostat) Up-regulates Progranulin Transcription RATIONAL THERAPEUTIC APPROACH TO FRONTOTEMPORAL DEMENTIA
err2011-05-01
err140
errOAAI
errCenik, Basar; Sephton, Chantelle F.; Dewey, Colleen M.; Xian, Xunde; Wei, Shuguang; Yu, Kimberley; Niu, Wenze; Coppola, Giovanni; Coughlin, Sarah E.; Lee, Suzee E.; Dries, Daniel R.; Almeida, Sandra; Geschwind, Daniel H.; Gao, Fen-Biao; Miller, Bruce L.; Farese, Robert V., Jr.; Posner, Bruce A.; Yu, Gang; Herz, Joachim
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A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma
err2011-05-01
err60
PREAI
errPillai, Prajit; Desai, Shraddha; Patel, Rekha; Sajan, Mini; Farese, Robert; Ostrov, David; Acevedo-Duncan, Mildred
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Insulin Signaling and Insulin Sensitizing in Muscle and Liver of Obese Monkeys: Peroxisome Proliferator-Activated Receptor Gamma Agonist Improves Defective Activation of Atypical Protein Kinase C
err2011-01-15
err9
errOAAI
errOrtmeyer, Heidi K.; Sajan, Mini P.; Miura, Atsushi; Kanoh, Yoshinore; Rivas, Jose; Li, Yongxiang; Standaert, Mary L.; Ryan, Alice S.; Bodkin, Noni L.; Farese, Robert V.; Hansen, Barbara C.
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Insulin resistance for glucose uptake and Akt2 phosphorylation in the soleus, but not epitrochlearis, muscles of old vs. adult rats
err2010-06-01
err26
errOAAI
errSharma, Naveen; Arias, Edward B.; Sajan, Mini P.; MacKrell, James G.; Bhat, Abhijit D.; Farese, Robert V.; Cartee, Gregory D.
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Atypical Protein Kinase C Activity in the Hypothalamus Is Required for Lipopolysaccharide-Mediated Sickness Responses
err2009-10-09
err20
errOAAI
errThaler, Joshua P.; Choi, Sun Ju; Sajan, Mini P.; Ogimoto, Kayoko; Nguyen, Hong T.; Matsen, Miles; Benoit, Stephen C.; Wisse, Brent E.; Farese, Robert V.; Schwartz, Michael W.
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The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFκB in obesity
err2009-06-01
err57
errOAAI
errSajan, Mini P.; Standaert, Mary L.; Nimal, Sonali; Varanasi, Usha; Pastoor, Tina; Mastorides, Stephen; Braun, Ursula; Leitges, Michael; Farese, Robert V.
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