Mark R. Philips - Publications, H-index & Citations

Mark R. Philips

nyu langone medical center

63H指数

225论文数

1.4W被引数

收录论文 33

发表时间

UPF1 deficiency enhances mitochondrial ROS which promotes an immunosuppressive microenvironment in pancreatic ductal adenocarcinoma UPF1 缺乏增强了线粒体 ROS，这促进了胰腺导管腺癌中的免疫抑制性微环境。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-08-06

PREAI

Su, Wenjuan; Rossi, Juan Kochen; Chen, Ting; Branco, Cristina; Wong, Kwok-kin; Simeone, Diane M.; Gardner, Lawrence B.; Philips, Mark R.

RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-06-15

OAAI

Ren, Jian-Gan; Xing, Bowen; Lv, Kaoshen; O'Keefe, Rachel A.; Wu, Mengfang; Wang, Ruoxing; Bauer, Kaylyn M.; Ghazaryan, Arevik; Burslem, George M.; Zhang, Jing; O'Connell, Ryan M.; Pillai, Vinodh; Hexner, Elizabeth O.; Philips, Mark R.; Tong, Wei

Differential functions of the KRAS splice variants

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2023-05-24

PREAI

Rossi, Juan Kochen; Nuevo-Tapioles, Cristina; Philips, Mark R.

Origin and Evolution of RAS Membrane Targeting

ONCOGENE

IF7.3

2023-04-08

OAAI

Garcia-Espana, Antonio; Philips, Mark R. R.

Consensus on the RAS dimerization hypothesis: Strong evidence for lipid-mediated clustering but not for G-domain-mediated interactions 关于RAS二聚化假说的共识: 脂质介导的聚类而不是G域介导的相互作用的有力证据

MOLECULAR CELL

IF16.6

2023-04-01

OAAI

Simanshu, Dhirendra K.; Philips, Mark R.; Hancock, John F.

Article Palmitoylation and PDE6d regulate membrane-compartment-specific substrate ubiquitylation and degradation

CELL REPORTS

IF6.9

2023-01-01

OAAI

Liang, David; Jiang, Liping; Ahmed Bhat, Sameer; Missiroli, Sonia; Perrone, Mariasole; Lauriola, Angela; Adhikari, Ritika; Gudur, Anish; Vasi, Zahra; Ahearn, Ian; Guardavaccaro, Daniele; Giorgi, Carlotta; Philips, Mark; Kuchay, Shafi

Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters

NATURE COMMUNICATIONS

IF15.7

2021-08-12

OAAI

Parker, Seth J.; Encarnacion-Rosado, Joel; Hollinshead, Kate E. R.; Hollinshead, David M.; Ash, Leonard J.; Rossi, Juan A. K.; Lin, Elaine Y.; Sohn, Albert S. W.; Philips, Mark R.; Jones, Drew R.; Kimmelman, Alec C.

Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells

NATURE COMMUNICATIONS

IF15.7

2021-07-13

OAAI

Chen, Wei-Ching; To, Minh D.; Westcott, Peter M. K.; Delrosario, Reyno; Kim, Il-Jin; Philips, Mark; Tran, Quan; Bollam, Saumya R.; Goodarzi, Hani; Bayani, Nora; Mirzoeva, Olga; Balmain, Allan

ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer

NATURE CANCER

IF28.5

2021-05-17

OAAI

Deng, Jiehui; Thennavan, Aatish; Dolgalev, Igor; Chen, Ting; Li, Jie; Marzio, Antonio; Poirier, John T.; Peng, David H.; Bulatovic, Mirna; Mukhopadhyay, Subhadip; Silver, Heather; Papadopoulos, Eleni; Pyon, Val; Thakurdin, Cassandra; Han, Han; Li, Fei; Li, Shuai; Ding, Hailin; Hu, Hai; Pan, Yuanwang; Weerasekara, Vajira; Jiang, Baishan; Wang, Eric S.; Ahearn, Ian; Philips, Mark; Papagiannakopoulos, Thales; Tsirigos, Aristotelis; Rothenberg, Eli; Gainor, Justin; Freeman, Gordon J.; Rudin, Charles M.; Gray, Nathanael S.; Hammerman, Peter S.; Pagano, Michele; Heymach, John V.; Perou, Charles M.; Bardeesy, Nabeel; Wong, Kwok-Kin

NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane

LIFE SCIENCE ALLIANCE

IF2.9

2021-02-12

OAAI

Ahearn, Ian M.; Court, Helen R.; Siddiqui, Farid; Abankwa, Daniel; Philips, Mark R.

A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells

ELIFE

IF0

2021-02-02

OAAI

Chen, Xue; Yao, Haidong; Kashif, Muhammad; Revechon, Gwladys; Eriksson, Maria; Hu, Jianjiang; Wang, Ting; Liu, Yiran; Tuksammel, Elin; Stromblad, Staffan; Ahearn, Ian M.; Philips, Mark R.; Wiel, Clotilde; Ibrahim, Mohamed X.; Bergo, Martin O.

Breaking Tradition to Bridge Bench and Bedside: Accelerating the MD-PhD-Residency Pathway

ACADEMIC MEDICINE

IF5.2

2021-01-12

OAAI

Modrek, Aram S.; Tanese, Naoko; Placantonakis, Dimitris G.; Sulman, Erik P.; Rivera, Rafael, Jr.; Du, Kevin L.; Gerber, Naamit K.; David, Gregory; Chesler, Mitchell; Philips, Mark R.; Cangiarella, Joan

Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-11-30

OAAI

Zhou, Mo; Kuruvilla, Leena; Shi, Xiarong; Viviano, Stephen; Ahearn, Ian M.; Amendola, Caroline R.; Su, Wenjuan; Badri, Sana; Mahaffey, James; Fehrenbacher, Nicole; Skok, Jane; Schlessinger, Joseph; Turk, Benjamin E.; Calderwood, David A.; Philips, Mark R.

Selective Alanine Transporter Utilization Creates a Targetable Metabolic niche in Pancreatic Cancer

CANCER DISCOVERY

IF33.3

2020-07-01

115

OAAI

Parker, Seth J.; Amendola, Caroline R.; Hollinshead, Kate E. R.; Yu, Qijia; Yamamoto, Keisuke; Encarnacion-Rosado, Joel; Rose, Rebecca E.; LaRue, Madeleine M.; Sohn, Albert S. W.; Biancur, Doug E.; Paulo, Joao A.; Gygi, Steven P.; Jones, Drew R.; Wang, Huamin; Philips, Mark R.; Bar-Sagi, Dafna; Mancias, Joseph D.; Kimmelman, Alec C.

A tribute to Gerald Weissmann (1930-2019) OBITUARY 向杰拉尔德·魏斯曼 (1930-2019) ob告致敬

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2019-10-07

OAAI

Abramson, Steven B.; Anderson, Paul J.; Buyon, Jill P.; Cronstein, Bruce N.; Pederson, Thoru; Philips, Mark R.; Serhan, Charles N.

GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2019-06-17

OAAI

Kuchay, Shafi; Wang, Hui; Marzio, Antonio; Jain, Kunj; Homer, Harrison; Fehrenbacher, Nicole; Philips, Mark R.; Zheng, Ning; Pagano, Michele

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-06-10

OAAI

Marin-Ramos, Nagore I.; Balabasquer, Moises; Ortega-Nogales, Francisco J.; Torrecillas, Ivan R.; Gil-Ordonez, Ana; Marcos-Ramiro, Beatriz; Aguilar-Garrido, Pedro; Cushman, Ian; Romero, Antonio; Medrano, Francisco J.; Gajate, Consuelo; Mollinedo, Faustino; Philips, Mark R.; Campillo, Mercedes; Gallardo, Miguel; Martin-Fontecha, Mar; Lopez-Rodriguez, Maria L.; Ortega-Gutierrez, Silvia

Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation 整合素激活中FAK调节的RIAM自抑制的分子基础

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-02-07

OAAI

Chang, Yu-Chung; Su, Wenjuan; Cho, Eun-ah; Zhang, Hao; Huang, Qingqiu; Philips, Mark R.; Wu, Jinhua

K-Ras Lys-42 is crucial for its signaling, cell migration, and invasion

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-11-01

OAAI

Choi, Byeong Hyeok; Philips, Mark R.; Chen, Yuan; Lu, Lou; Dai, Wei