logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
Z

Zhike Lu

Westlake Laboratory

44H指数
133论文数
3.8W被引数
收录论文 47
发表时间
logo
Improving the efficiency of high-fidelity Cas9 by enhancing PAM-distal interactions通过增强PAM-远端相互作用提高高保真Cas9的效率
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2026-03-18
err0
PREAI
errRong Zheng; Zhike Lu; Rongwei Wei; Young-Cheul Shin; Jiang Du; Qingfeng Zhang; Jianbo Li; Xiaoqi Wang; Yi Wei; Botao Liu; Yang Chen; Lihong Ding; Heng Zhang; Hui Chen; Jing Huang; Lijia Ma
err分享
err收藏
Loop engineering improves prime editing efficiency环工程提高了碱基编辑效率
errMolecular Therapy Nucleic Acids
IF6.1
err2025-11-06
err0
errOAAI
errBailun Li; Zhike Lu; Ting Zhou; Huilin Mou; Zhilin Zou; Keyi Yao; Zhenxing Yu; Wenyu Ma; Tingliang Wang; Miao He; Lijia Ma
err分享
err收藏
TAS-seq enables subcellular single-stranded adenosine profiling by signal peptide-assisted adenosine deaminationTAS-seq技术通过信号肽辅助的腺苷脱氨作用，实现了亚细胞水平的单链腺苷谱分析。
errCell Reports Methods
IF4.5
err2025-06-25
err0
errOAAI
errLixia Wang; Yangfan Zhou; Zhenxing Yu; Panfeng Wu; Zhike Lu; Lijia Ma
err分享
err收藏
The Transpeptidase Sortase A Binds Nucleic Acids and Mediates Mammalian Cell Labeling
errADVANCED SCIENCE
IF14.1
err2024-04-05
err0
errOAAI
errLiu, Yingzheng; Lu, Zhike; Wu, Panfeng; Liang, Zhaohui; Yu, Zhenxing; Ni, Ke; Ma, Lijia
err分享
err收藏
A top variant identification pipeline for protein engineering
errCELL SYSTEMS
IF7.7
err2024-02-01
err0
errOAAI
errChen, Hui; Lu, Zhike; Ma, Lijia
err分享
err收藏
Machine learning-based prediction models to guide the selection of Cas9 variants for efficient gene editing
errCELL REPORTS
IF6.9
err2024-02-01
err2
errOAAI
errLi, Jianbo; Wu, Panfeng; Cao, Zhoutao; Huang, Guanlan; Lu, Zhike; Yan, Jianfeng; Zhang, Heng; Zhou, Yangfan; Liu, Rong; Chen, Hui; Ma, Lijia; Luo, Mengcheng
err分享
err收藏
Optimized minimal genome-wide human sgRNA library (vol 13, 11569, 2023)
errSCIENTIFIC REPORTS
IF3.9
err2023-08-16
err0
errOAAI
errZhou, Yangfan; Wang, Lixia; Lu, Zhike; Yu, Zhenxing; Ma, Lijia
err分享
err收藏
Optimized minimal genome-wide human sgRNA library优化的最小全基因组人类sgRNA文库
errSCIENTIFIC REPORTS
IF3.9
err2023-07-18
err3
errOAAI
errZhou, Yangfan; Wang, Lixia; Lu, Zhike; Yu, Zhenxing; Ma, Lijia
err分享
err收藏
Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activities
errCELL DISCOVERY
IF12.5
err2023-05-16
err7
errOAAI
errZhang, Heng; Yan, Jianfeng; Lu, Zhike; Zhou, Yangfan; Zhang, Qingfeng; Cui, Tingting; Li, Yini; Chen, Hui; Ma, Lijia
err分享
err收藏
PEAC-seq adopts Prime Editor to detect CRISPR off-target and DNA translocationPeac-seq采用Prime编辑器检测CRISPR脱靶和DNA易位
errNATURE COMMUNICATIONS
IF15.7
err2022-12-12
err9
errOAAI
errYu, Zhenxing; Lu, Zhike; Li, Jingjing; Wang, Yingying; Wu, Panfeng; Li, Yini; Zhou, Yangfan; Li, Bailun; Zhang, Heng; Liu, Yingzheng; Ma, Lijia
err分享
err收藏
An in-library ligation strategy and its application in CRISPR/Cas9 screening of high-order gRNA combinations
errNUCLEIC ACIDS RESEARCH
IF13.1
err2022-06-07
err3
errOAAI
errLu, Zhike; Ni, Ke; Wang, Yingying; Zhou, Yangfan; Li, Yini; Yan, Jianfeng; Song, Qingkai; LiU, Min; Xu, Yujun; Yu, Zhenxing; Guo, Tiannan; Ma, Lijia
err分享
err收藏
New Chromatin Run-On Reaction Enables Global Mapping of ActiveRNA Polymerase Locations in an Enrichment-free Manner
errACS CHEMICAL BIOLOGY
IF3.8
err2022-03-18
err3
PREAI
errGao, Minsong; Li, Yini; Shu, Xiao; Dai, Pengfei; Cao, Jie; An, Yunyun; Li, Tengwei; Huang, Ye; Wang, Fengqin; Lu, Zhike; Meng, Fei-Long; Feng, Xin-Hua; Ma, Lijia; Liu, Jianzhao
err分享
err收藏
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma (vol 18, 163, 2019)
errMOLECULAR CANCER
IF33.9
err2020-09-04
err7
errOAAI
errHou, Jiajie; Zhang, He; Liu, Jun; Zhao, Zhenjun; Wang, Jianye; Lu, Zhike; Hu, Bian; Zhou, Jiankui; Zhao, Zhicong; Feng, Mingxuan; Zhang, Haiyan; Shen, Bin; Huang, Xingxu; Sun, Beicheng; Smyth, Mark J.; He, Chuan; Xia, Qiang
err分享
err收藏
Direct-seq: programmed gRNA scaffold for streamlined scRNA-seq in CRISPR screen
errGENOME BIOLOGY
IF9.4
err2020-06-08
err17
errOAAI
errSong, Qingkai; Ni, Ke; Liu, Min; Li, Yini; Wang, Lixia; Wang, Yingying; Liu, Yingzheng; Yu, Zhenxing; Qi, Yinyao; Lu, Zhike; Ma, Lijia
err分享
err收藏
A metabolic labeling method detects m6A transcriptome-wide at single base resolution
errNATURE CHEMICAL BIOLOGY
IF13.7
err2020-04-27
err181
PREAI
errShu, Xiao; Cao, Jie; Cheng, Mohan; Xiang, Siying; Gao, Minsong; Li, Ting; Ying, Xiner; Wang, Fengqin; Yue, Yanan; Lu, Zhike; Dai, Qing; Cui, Xiaolong; Ma, Lijia; Wang, Yizhen; He, Chuan; Feng, Xinhua; Liu, Jianzhao
err分享
err收藏
The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine?containing mRNAs
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2019-12-01
err108
errOAAI
errHsu, Phillip J.; Shi, Hailing; Zhu, Allen C.; Lu, Zhike; Miller, Nimrod; Edens, Brittany M.; Ma, Yongchao C.; He, Chuan
err分享
err收藏
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma
errMOLECULAR CANCER
IF33.9
err2019-11-18
err256
errOAAI
errHou, Jiajie; Zhang, He; Liu, Jun; Zhao, Zhenjun; Wang, Jianye; Lu, Zhike; Hu, Bian; Zhou, Jiankui; Zhao, Zhicong; Feng, Mingxuan; Zhang, Haiyan; Shen, Bin; Huang, Xingxu; Sun, Beicheng; He, Chuan; Xia, Qiang
err分享
err收藏
Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus
errNATURE COMMUNICATIONS
IF15.7
err2019-10-09
err75
errOAAI
errXue, Miaoge; Zhao, Boxuan Simen; Zhang, Zijie; Lu, Mijia; Harder, Olivia; Chen, Phylip; Lu, Zhike; Li, Anzhong; Ma, Yuanmei; Xu, Yunsheng; Liang, Xueya; Zhou, Jiyong; Niewiesk, Stefan; Peeples, Mark E.; He, Chuan; Li, Jianrong
err分享
err收藏
Hypoxia regulates m6A-reader YTHDF2 to fuel cancer-promoting inflammation in hepatocellular carcinoma
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errHou, Jiajie; Zhang, He; Liu, Jun; Zhao, Zhenjun; Wang, Jianye; Lu, Zhike; Hu, Bian; Zhou, Jiankui; Zhao, Zhicong; Feng, Mingxuan; Zhang, Haiyan; Shen, Bin; Huang, Xingxu; Sun, Beicheng; Smyth, Mark J.; He, Chuan; Xia, Qiang
err分享
err收藏
m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade
errNATURE COMMUNICATIONS
IF15.7
err2019-06-25
err544
errOAAI
errYang, Seungwon; Wei, Jiangbo; Cui, Yan-Hong; Parka, Gayoung; Shah, Palak; Deng, Yu; Aplin, Andrew E.; Lu, Zhike; Hwang, Seungmin; He, Chuan; He, Yu-Ying
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
M
Mark J. Smyth
H 指数: 172 · 论文数: 1.4K
C
C. David Allis
H 指数: 164 · 论文数: 433
C
Chuan He
H 指数: 161 · 论文数: 979
B
Bing Ren
H 指数: 131 · 论文数: 543
E
Eric Verdin
H 指数: 131 · 论文数: 459
查看更多