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APN1125: A clinical stage α7 nicotinic acetylcholine receptor partial agonist Koelsch, Gerald; Detke, Michael J.; Stevens, Karen E.; Meltzer, Leonard T.; Terry, Alvin V., Jr.; Callahan, Patrick M.; Yoshimura, Ryan F.; Bilcer, Geoffrey; Anderson, Paul C.; Ng, John; Ng, Raymond; Kelly, Terence A. 分享 收藏
Discovery of BI 207524, an Indole Diamide NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection Beaulieu, Pierre L.; Anderson, Paul C.; Bethell, Richard; Boes, Michael; Bousquet, Yves; Brochu, Christian; Ley, Michael G. Cording; Fazal, Gulrez; Gameau, Michel; Gillard, James R.; Kawai, Stephen; Marquis, Martin; McKercher, Ginette; Poupart, Marc-Andre; Stammers, Timothy; Thavonekham, Bounkham; Wernic, Dominik; Duan, Jianmin; Kukolj, George 分享 收藏
PRECLINICAL CHARACTERIZATION OF THE HEPATITIS C VIRUS NS5B POLYMERASE NON-NUCLEOSIDE INHIBITOR BI 207127 Beaulieu, P. L.; Anderson, P. C.; Brochu, C.; Boes, M.; Cordingley, M.; Duan, J.; Garneau, M.; Lagrace, L.; Marquis, M.; McKercher, G.; Poupart, B.; Rancourt, J.; Stammers, T.; Tsantrizos, Y. S.; Kukolj, G. 分享 收藏
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TOTAL SYNTHESIS OF BOTH (+)-COMPACTIN AND (+)-MEVINOLIN - A GENERAL STRATEGY BASED ON THE USE OF A SPECIAL TITANIUM REAGENT FOR DICARBONYL COUPLING CLIVE, DLJ; MURTHY, KSK; WEE, AGH; PRASAD, JS; DASILVA, GVJ; MAJEWSKI, M; ANDERSON, PC; EVANS, CF; HAUGEN, RD; HEERZE, LD; BARRIE, JR 分享 收藏
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2′,6′-dimethylphenoxyacetyl:: A new achiral high affinity P3-P2 ligand for peptidomimetic-based HIV protease inhibitors Beaulieu, PL; Anderson, PC; Cameron, DR; Croteau, G; Gorys, V; Grand-Maitre, C; Lamarre, D; Liard, F; Paris, W; Plamondon, L; Soucy, F; Thibeault, D; Wernic, D; Yoakim, C; Pav, S; Tong, L 分享 收藏
Discovery of non-peptidic P2-P3 butanediamide renin inhibitors with high oral efficacy Simoneau, B; Lavallée, P; Anderson, PC; Bailey, M; Bantle, G; Berthiaume, S; Chabot, C; Fazal, G; Halmos, T; Ogilvie, WW; Poupart, MA; Thavonekham, B; Xin, ZL; Thibeault, D; Bolger, G; Panzenbeck, M; Winquist, R; Jung, GL 分享 收藏
Potent HIV protease inhibitors containing a novel (hydroxyethyl)amide isostere Beaulieu, PL; Wernic, D; Abraham, A; Anderson, PC; Bogri, T; Bousquet, Y; Croteau, G; Guse, I; Lamarre, D; Liard, F; Paris, W; Thibeault, D; Pav, S; Tong, L 分享 收藏
Practical, stereoselective synthesis of palinavir, a potent HIV protease inhibitor Beaulieu, PL; Lavallee, P; Abraham, A; Anderson, PC; Boucher, C; Bousquet, Y; Duceppe, JS; Gillard, J; Gorys, V; GrandMaitre, C; Grenier, L; Guindon, Y; Guse, I; Plamondon, L; Soucy, F; Valois, S; Wernic, D; Yoakim, C 分享 收藏
Antiviral properties of palinavir, a potent inhibitor of the human immunodeficiency virus type 1 protease Lamarre, D; Croteau, G; Wardrop, E; Bourgon, L; Thibeault, D; Clouette, C; Vaillancourt, M; Cohen, E; Pargellis, C; Yoakim, C; Anderson, P 分享 收藏