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S

Stephen Orena

infectious diseases research collaboration
H指数:15
被引数:1,606

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In vitro antiplasmodial activity, acute toxicity and phytochemical quantification of selected medicinal plants used for the management of uncomplicated malaria in eastern Uganda

体外抗疟原虫活性、急性毒性及用于管理东部乌干达非复杂疟疾的选定药用植物的植物化学成分定量分析

Journal of Ethnopharmacology
IF5.4
2025-12-060
PRE
Samuel Baker Obakiro; Catherine Nabitandikwa; Kenedy Kiyimba; Moses Ocan; Yahaya Gavamukulya; Moses Andima; Tonny Wotoyitide Lukwago; Richard Maseruka; Mercy Chebijira; Moses Opio; Joseph Francis Hokello; Dan Kibuule; Alice Nabatanzi; Stephen Orena; Paul Waako; Richard Oriko Owor
Optimization of Prodiginines as Single-Dose Curative Antimalarials

单剂量根治性抗疟药Prodiginines的优化

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-11-010
PRE
Kumar, Amrendra; Li, Yuexin; Zhang, Xiaowei; Gaddam, Mahesh; Caridha, Diana; Madejczyk, Michael S.; Jin, Xiannu; Dennis, William E.; Chetree, Ravi; Blount, Cameron; DeLuca, Jesse; Vuong, Chau; Kudyba, Karl; Roncal, Norma; Ashraf, Kutub; Lee, Patricia J.; Pannone, Kristina; Leed, Susan; Dinh, Hieu T.; Mdaki, Kennedy; Navarrete, Kimberly; Charlton, Jordan; Binauhan, Angely J.; Qahash, Tarrick; Kibe, Kevin Mugambi; Shoue, Douglas A.; Checkley, Lisa; Ferdig, Michael T.; Chim-Ong, Anongruk; Cui, Liwang; Orena, Stephen; Byaruhanga, Oswald; Assimwe, Jackson; Tibagambirwa, Innocent; Chithanna, Sivanna; Dodean, Rozalia A.; Legac, Jennifer; Kreutzfeld, Oriana; Rosenthal, Philip J.; Cooper, Roland A.; Reynolds, Kevin A.; Roth, Alison; Kelly, Jane X.; Kancharla, Papireddy
Efficacies of artemether–lumefantrine, artesunate–amodiaquine, dihydroartemisinin–piperaquine, and artesunate–pyronaridine for the treatment of uncomplicated Plasmodium falciparum malaria in children aged 6 months to 10 years in Uganda: a randomised, open-label, phase 4 clinical trial

乌干达6个月至10岁儿童中，治疗无并发症恶性疟原虫疟疾的青蒿琥酯-苯芴醇、青蒿素-阿莫地喹、双氢青蒿素-哌喹和青蒿素-哌喹的疗效：一项随机、开放标签、IV期临床试验

The Lancet Infectious Diseases
IF0
2025-08-190
PRE
Moses R Kamya; Joaniter I Nankabirwa; Chris Ebong; Victor Asua; Moses Kiggundu; Stephen Orena; Martin Okitwi; Stephen Tukwasibwe; Bosco Agaba; Daniel Kyabayinze; Jimmy Opigo; Damian Rutazana; Benjamin Binagwa; Edward Mugwanya; Shakira Babirye; Gloria Sebikaari; Patrick M Condo; Grace Appiah; Sam L Nsobya; Melissa D Conrad
Identifying a next-generation antimalarial trioxolane in a landscape of artemisinin partial resistance

在青蒿素部分耐药背景下鉴定下一代抗疟三氧杂环戊烷类药物

Science Advances
IF12.5
2025-08-080
OA
Matthew T. Klope; Poulami Talukder; Brian R. Blank; Sevil Chelebieva; Jun Chen; Shaun D. Fontaine; Ryan L. Gonciarz; Priyadarshini Jaishankar; Grace J. Lee; Jennifer Legac; Vineet Mathur; Avani Narayan; Martin Okitwi; Stephen Orena; Nicholas S. Settineri; Juan A. Tapia; Yoweri Taremwa; Patrick K. Tumwebaze; Aswathy Vinod; Jeremy N. Burrows; Philip J. Rosenthal; Roland A. Cooper; Adam R. Renslo
Development of Next-Generation Antimalarial Acridones with Radical Cure Potential

下一代具有自由基治愈潜力的抗疟喹诺酮类化合物的发展

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-04-030
PRE
Dodean, Rozalia A.; Li, Yuexin; Zhang, Xiaowei; Caridha, Diana; Madejczyk, Michael S.; Jin, Xiannu; Dennis, William E.; Chetree, Ravi; Kudyba, Karl; Mcenearney, Sharon; Lee, Patricia J.; Blount, Cameron; Deluca, Jesse; Vuong, Chau; Pannone, Kristina; Dinh, Hieu T.; Mdaki, Kennedy; Leed, Susan; Martin, Monica L.; Pybus, Brandon S.; Pou, Sovitj; Winter, Rolf W.; Liebman, Katherine M.; Williams, Rachel; Kumar, Amrendra; Chim-Ong, Anongruk; Cui, Liwang; Orena, Stephen; Assimwe, Jackson; Tibagambirwa, Innocent; Byaruhanga, Oswald; Angutoko, Patrick; Legac, Jennifer; Kreutzfeld, Oriana; Rosenthal, Philip J.; Cooper, Roland A.; Nilsen, Aaron; Riscoe, Michael K.; Roth, Alison; Kancharla, Papireddy; Kelly, Jane X.
The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh Plasmodium falciparum isolates

延长恢复环阶段存活试验是新鲜恶性疟原虫分离株青蒿素敏感性表型的可扩展替代方法

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2024-12-050
PRE
Okitwi, Martin; Shoue, Douglas A.; Checkley, Lisa A.; Orena, Stephen; Ceja, Frida G.; Taremwa, Yoweri; Tumwebaze, Patrick K.; Katairo, Thomas; Byaruhanga, Oswald; Sievert, Mackenzie A. C.; Garg, Shreeya; Kreutzfeld, Oriana K.; Legac, Jennifer; Bailey, Jeffrey A.; Nsobya, Sam L.; Conrad, Melissa D.; Rosenthal, Philip J.; Ferdig, Michael T.; Cooper, Roland A.
Ex vivo susceptibilities to ganaplacide and diversity in potential resistance mediators in Ugandan Plasmodium falciparum isolates

乌干达恶性疟原虫分离株对ganaplacide的离体敏感性和潜在抗性介质的多样性

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2024-09-040
PRE
Kreutzfeld, Oriana; Orena, Stephen; Okitwi, Martin; Tumwebaze, Patrick K.; Byaruhanga, Oswald; Katairo, Thomas; Conrad, Melissa D.; Legac, Jennifer; Garg, Shreeya; Crudale, Rebecca; Aydemir, Ozkan; Giesbrecht, David; Nsobya, Samuel L.; Blasco, Benjamin; Duffey, Maelle; Rouillier, Melanie; Bailey, Jeffrey A.; Cooper, Roland A.; Rosenthal, Philip J.
Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline
MICROBIOLOGY SPECTRUM
IF3.8
2023-06-154
OAAI
Kreutzfeld, Oriana; Tumwebaze, Patrick K.; Okitwi, Martin; Orena, Stephen; Byaruhanga, Oswald; Katairo, Thomas; Conrad, Melissa D.; Rasmussen, Stephanie A.; Legac, Jennifer; Aydemir, Ozkan; Giesbrecht, David; Forte, Barbara; Campbell, Peter; Smith, Alasdair; Kano, Hiroki; Nsobya, Samuel L.; Blasco, Benjamin; Duffey, Maelle; Bailey, Jeffrey A.; Cooper, Roland A.; Rosenthal, Philip J.
Susceptibilities of Ugandan Plasmodium falciparum Isolates to Proteasome Inhibitors

乌干达恶性疟原虫分离株对蛋白酶体抑制剂的敏感性

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2022-10-185
OA
Garg, Shreeya; Kreutzfeld, Oriana; Chelebieva, Sevil; Tumwebaze, Patrick K.; Byaruhanga, Oswald; Okitwi, Martin; Orena, Stephen; Katairo, Thomas; Nsobya, Samuel L.; Conrad, Melissa D.; Aydemir, Ozkan; Legac, Jennifer; Gould, Alexandra E.; Bayles, Brett R.; Bailey, Jeffrey A.; Duffey, Maelle; Lin, Gang; Kirkman, Laura A.; Cooper, Roland A.; Rosenthal, Philip J.
Associations between Varied Susceptibilities to PfATP4 Inhibitors and Genotypes in Ugandan Plasmodium falciparum Isolates
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2021-09-172
OA
Kreutzfeld, Oriana; Rasmussen, Stephanie A.; Ramanathan, Aarti A.; Tumwebaze, Patrick K.; Byaruhanga, Oswald; Katairo, Thomas; Asua, Victor; Okitwi, Martin; Orena, Stephen; Legac, Jennifer; Conrad, Melissa D.; Nsobya, Samuel L.; Aydemir, Ozkan; Bailey, Jeffrey; Duffey, Maelle; Bayles, Brett R.; Vaidya, Akhil B.; Cooper, Roland A.; Rosenthal, Philip J.
Decreased Susceptibility to Dihydrofolate Reductase Inhibitors Associated With Genetic Polymorphisms in Ugandan Plasmodium falciparum Isolates

乌干达恶性疟原虫分离株对与遗传多态性相关的二氢叶酸还原酶抑制剂的易感性降低

JOURNAL OF INFECTIOUS DISEASES
IF4.5
2021-08-307
OA
Kreutzfeld, Oriana; Tumwebaze, Patrick K.; Byaruhanga, Oswald; Katairo, Thomas; Okitwi, Martin; Orena, Stephen; Rasmussen, Stephanie A.; Legac, Jennifer; Conrad, Melissa D.; Nsobya, Sam L.; Aydemir, Ozkan; Bailey, Jeffrey A.; Duffey, Maelle; Cooper, Roland A.; Rosenthal, Philip J.
cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV:: Synthesis and in vitro, in vivo, and X-ray crystallographic characterization
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2006-05-0241
PREAI
Wright, Stephen W.; Ammirati, Mark J.; Andrews, Kim M.; Brodeur, Anne M.; Danley, Dennis E.; Doran, Shawn D.; Lillquist, Jay S.; McClure, Lester D.; McPherson, R. Kirk; Orena, Stephen J.; Parker, Janice C.; Polivkova, Jana; Qiu, Xiayang; Soeller, Walter C.; Soglia, Carolyn B.; Treadway, Judith L.; VanVolkenburg, Maria A.; Wang, Hong; Wilder, Donald C.; Olson, Thanh V.

研究方向

暂未获取到该数据
R
Roland A. Cooper
H 指数:34论文数:91被引数:5,941
P
Philip J. Rosenthal
H 指数:100论文数:699被引数:3.3万
M
Martin Okitwi
H 指数:7论文数:33被引数:331
O
Oswald Byaruhanga
H 指数:8论文数:46被引数:564
J
Jennifer Legac
H 指数:24论文数:85被引数:2,104
P
Patrick K. Tumwebaze
H 指数:21论文数:60被引数:1,718
M
Melissa D. Conrad
H 指数:36论文数:123被引数:4,990
S
Samuel L. Nsobya
H 指数:36论文数:140被引数:4,141
T
Thomas Katairo
H 指数:11论文数:61被引数:790
O
Oriana Kreutzfeld
H 指数:6论文数:18被引数:106