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A

Athanassios Dovas

Columbia University
H指数:25
被引数:3,273

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Convection-Enhanced Delivery of Topotecan Induces IL-1β-Associated Inflammation in Glioblastoma

拓扑替康的增强对流递送诱导胶质母细胞瘤中IL-1β相关的炎症

Neurosurgery
IF3.9
2026-04-010
PRE
Tang, Anthony J.; Teasley, Damian E.; Dadario, Nicholas B.; Chen, Alan; Rolfe, Nathaniel; Amini, Misha; Ifediora, Nkechime; Dees, Mitchell; Mela, Angeliki; Dovas, Athanassios; Pereira, Brianna; Viswanathan, Ashwin; Mahajan, Aayushi; Humala, Nelson; Furnari, Julia; Kotidis, Corina; Haile, Hannah; Khoury, Nadine; Adapa, Arjun; Winans, Nathan J.; Argenziano, Michael G.; Sperring, Colin; Yoh, Nina; Lei, Liang; Gill, Brian J.; Sims, Peter; Grinband, Jack; Canoll, Peter D.; Bruce, Jeffrey N.
HUMAN AND MOUSE PERITUMORAL SLICES DEMONSTRATE MTOR-DEPENDENT GABAERGIC NEURONAL DYSFUNCTION IN GLIOMA

人源和鼠源肿瘤周切片显示胶质瘤中存在mTOR依赖的GABA能神经元功能障碍

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Viswanathan, Ashwin; Conboy, Karen; Wu, Xiaoping; Merricks, Edward M.; Young, Serina B.; Pereira, Brianna; Dovas, Athanassios; Goldberg, Alexander R.; Mahajan, Aayushi; Humala, Nelson; Furnari, Julia L.; Stucke, Clara; Amini, Misha; Rolfe, Nathaniel; McKhann II, Guy M.; Bruce, Jeffrey N.; Schevon, Catherine A.; Canoll, Peter; Gill, Brian J. A.
PROMINENT GLIOMA CALCIUM TRANSIENTS CAN BE REPEATEDLY TRIGGERED BY STIMULUS-EVOKED NEURONAL ACTIVITY AND PURINERGIC SIGNALING

显著胶质瘤钙瞬变可被刺激诱发的神经元活动和嘌呤能信号反复触发。

NEURO-ONCOLOGY
IF13.4
2025-11-010
PRE
Pereira, Brianna; Lodgher, Fatema; Yagielski, Alexis J.; Dovas, Athanassios; Mela, Angeliki; Viswanathan, Ashwin; Goldberg, Alexander R.; Conboy, Karen; Humala, Nelson; Mahajan, Aayushi; Amini, Misha; Bruce, Jeffrey N.; Schevon, Catherine A.; Gill, Brian J. A.; Peterka, Darcy S.; Hillman, Elizabeth M. C.; Canoll, Peter
IDH1(R132H) inhibitors enhance the sensitivity of IDH1-mutant glioma to cysteine deprivation and ferroptosis

IDH1(R132H)抑制剂增强了IDH1突变型胶质瘤对半胱氨酸剥夺和铁死亡的敏感性。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Mela, Angeliki; Brand, Abby; Mahajan, Aayushi; Dovas, Athanassios; Humala, Nelson; Kanangat, Smriti; Kleinstein, Allison; Leskinen, Sandra; Nguyen, Trang T. T.; Gao, Qiuqiang; Upadhyayula, Pavan S.; Guo, Jia; Gill, Brian J. A.; Siegelin, Markus D.; Sims, Peter A.; Stockwell, Brent R.; Bruce, Jeffrey N.; Canoll, Peter
MT-125 inhibits non-muscle myosin IIA and IIB and prolongs survival in glioblastoma

MT-125抑制非肌肉肌球蛋白IIA和IIB并延长胶质母细胞瘤患者的生存期

Cell
IF42.5
2025-06-100
OAAI
Rajappa S. Kenchappa; Laszlo Radnai; Erica J. Young; Natanael Zarco; Li Lin; Athanassios Dovas; Christian T. Meyer; Ashley Haddock; Alice Hall; Katalin Toth; Peter Canoll; Naveen K.H. Nagaiah; Gavin Rumbaugh; Michael D. Cameron; Theodore M. Kamenecka; Patrick R. Griffin; Courtney A. Miller; Steven S. Rosenfeld
A selective small-molecule agonist of G protein-gated inwardly-rectifying potassium channels reduces epileptiform activity in mouse models of tumor-associated and provoked seizures

G蛋白门控内向整流钾通道的选择性小分子激动剂可降低肿瘤相关性和诱发性癫痫样活动的小鼠模型中的癫痫样活动

NEUROPHARMACOLOGY
IF4.6
2025-03-010
PRE
Rifkin, Robert A.; Wu, Xiaoping; Pereira, Brianna; Gill, Brian JA.; Merricks, Edward M.; Michalak, Andrew J.; Goldberg, Alexander R.; Humala, Nelson; Dovas, Athanassios; Rai, Ganesha; Mckhann, Guy M.; Slesinger, Paul A.; Canoll, Peter; Schevon, Catherine
Glioma-induced alterations in excitatory neurons are reversed by mTOR inhibition

胶质瘤诱导的兴奋性神经元改变可通过mTOR抑制得到逆转

NEURON
IF15
2025-01-010
PRE
Goldberg, Alexander R.; Dovas, Athanassios; Torres, Daniela; Pereira, Brianna; Viswanathan, Ashwin; Das Sharma, Sohani; Mela, Angeliki; Merricks, Edward M.; Megino-Luque, Cristina; Mcinvale, Julie J.; Olabarria, Markel; Shokooh, Leila Abrishami; Zhao, Hanzhi T.; Chen, Cady; Kotidis, Corina; Calvaresi, Peter; Banu, Matei A.; Razavilar, Aida; Sudhakar, Tejaswi D.; Saxena, Ankita; Chokran, Cole; Humala, Nelson; Mahajan, Aayushi; Xu, Weihao; Metz, Jordan B.; Bushong, Eric A.; Boassa, Daniela; Ellisman, Mark H.; Hillman, Elizabeth M. C.; Hargus, Gunnar; Bravo-Cordero, Jose Javier; McKhann Ii, Guy M.; Gill, Brian J. A.; Rosenfeld, Steven S.; Schevon, Catherine A.; Bruce, Jeffrey N.; Sims, Peter A.; Peterka, Darcy S.; Canoll, Peter
CHEMOTHERAPY INDUCED IMMUNOGENIC RESPONSE IN GLIOMA AND IMPLICATIONS FOR THERAPEUTIC STRATEGIES
NEURO-ONCOLOGY
IF13.4
2024-11-110
PRE
Teasley, Damian; Dadario, Nicholas; Lei, Liang; Sperring, Colin; Khoury, Nadine; Rolfe, Nathaniel; Kristt, Melanie; Mela, Angeliki; Ifedoria, Nkechime; Kotidis, Corina; Zhao, Wenting; Furnari, Julia; Mahajan, Aayushi; Pereira, Brianna; Argenziano, Michael; Winans, Nathan; Yoh, Nina; Humala, Nelson; Dovas, Athanassios; Karan, Charles; Gill, Brian; Sims, Peter; Bruce, Jeffrey; Canoll, Peter
A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma
EMBO JOURNAL
IF8.3
2024-08-271
OAAI
Banu, Matei A.; Dovas, Athanassios; Argenziano, Michael G.; Zhao, Wenting; Sperring, Colin P.; Cuervo Grajal, Henar; Liu, Zhouzerui; Higgins, Dominique M. O.; Amini, Misha; Pereira, Brianna; Ye, Ling F.; Mahajan, Aayushi; Humala, Nelson; Furnari, Julia L.; Upadhyayula, Pavan S.; Zandkarimi, Fereshteh; Nguyen, Trang T. T.; Teasley, Damian; Wu, Peter B.; Hai, Li; Karan, Charles; Dowdy, Tyrone; Razavilar, Aida; Siegelin, Markus D.; Kitajewski, Jan; Larion, Mioara; Bruce, Jeffrey N.; Stockwell, Brent R.; Sims, Peter A.; Canoll, Peter
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
CELL STEM CELL
IF20.4
2024-05-011
OAAI
Al-Dalahmah, Osama; Lam, Matti; McInvale, Julie J.; Qu, Wenhui; Nguyen, Trang; Mun, Jeong-Yeon; Kwon, Sam; Ifediora, Nkechime; Mahajan, Aayushi; Humala, Nelson; Winters, Tristan; Angeles, Ellen; Jakubiak, Kelly A.; Kuhn, Rebekka; Kim, Yoon A.; De Rosa, Maria Caterina; Doege, Claudia A.; Paryani, Fahad; Flowers, Xena; Dovas, Athanassios; Mela, Angeliki; Lu, Hong; DeTure, Michael A.; Vonsattel, Jean Paul; Wszolek, Zbigniew K.; Dickson, Dennis W.; Kuhlmann, Tanja; Zaehres, Holm; Schoeler, Hans R.; Sproul, Andrew A.; Siegelin, Markus D.; De Jager, Philip L.; Goldman, James E.; Menon, Vilas; Canoll, Peter; Hargus, Gunnar
Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states
NATURE COMMUNICATIONS
IF15.7
2023-05-0422
OAAI
Al-Dalahmah, Osama; Argenziano, Michael G. G.; Kannan, Adithya; Mahajan, Aayushi; Furnari, Julia; Paryani, Fahad; Boyett, Deborah; Save, Akshay; Humala, Nelson; Khan, Fatima; Li, Juncheng; Lu, Hong; Sun, Yu; Tuddenham, John F. F.; Goldberg, Alexander R. R.; Dovas, Athanassios; Banu, Matei A. A.; Sudhakar, Tejaswi; Bush, Erin; Lassman, Andrew B. B.; McKhann, Guy M. M.; Gill, Brian J. A.; Youngerman, Brett; Sisti, Michael B. B.; Bruce, Jeffrey N. N.; Sims, Peter A. A.; Menon, Vilas; Canoll, Peter
Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism
NATURE COMMUNICATIONS
IF15.7
2023-03-0262
OAAI
Upadhyayula, Pavan S.; Higgins, Dominique M.; Mela, Angeliki; Banu, Matei; Dovas, Athanassios; Zandkarimi, Fereshteh; Patel, Purvi; Mahajan, Aayushi; Humala, Nelson; Nguyen, Trang T. T.; Chaudhary, Kunal R.; Liao, Lillian; Argenziano, Michael; Sudhakar, Tejaswi; Sperring, Colin P.; Shapiro, Benjamin L.; Ahmed, Eman R.; Kinslow, Connor; Ye, Ling F.; Siegelin, Markus D.; Cheng, Simon; Soni, Rajesh; Bruce, Jeffrey N.; Stockwell, Brent R.; Canoll, Peter
Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma
CELL REPORTS
IF6.9
2022-06-0112
OAAI
Kenchappa, Rajappa S.; Dovas, Athanassios; Argenziano, Michael G.; Meyer, Christian T.; Stopfer, Lauren E.; Banu, Matei A.; Pereira, Brianna; Griffith, Jessica; Mohammad, Afroz; Talele, Surabhi; Haddock, Ashley; Zarco, Natanael; Elmquist, William; White, Forest; Sims, Peter; Quaranta, Vito; Sims, Peter; Canoll, Peter; Rosenfeld, Steven S.

研究方向

暂未获取到该数据
P
Peter Canoll
H 指数:77论文数:675被引数:2.2万
J
Jeffrey N. Bruce
H 指数:77论文数:666被引数:2.2万
B
Brian Gill
H 指数:17论文数:68被引数:2,287
N
Nelson Humala
H 指数:19论文数:88被引数:3,101
A
Aayushi Mahajan
H 指数:18论文数:102被引数:2,484
B
Brianna Pereira
H 指数:7论文数:24被引数:311
A
Angeliki Mela
H 指数:17论文数:76被引数:1,565
A
Alexander Goldberg
H 指数:23论文数:99被引数:2,777
P
Peter A. Sims
H 指数:58论文数:354被引数:1.4万
M
Matei A. Banu
H 指数:29论文数:121被引数:2,940