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A

Aayushi Mahajan

Cornell University
H指数:18
被引数:2,442

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Convection-Enhanced Delivery of Topotecan Induces IL-1β-Associated Inflammation in Glioblastoma

拓扑替康的增强对流递送诱导胶质母细胞瘤中IL-1β相关的炎症

Neurosurgery
IF3.9
2026-04-010
PRE
Tang, Anthony J.; Teasley, Damian E.; Dadario, Nicholas B.; Chen, Alan; Rolfe, Nathaniel; Amini, Misha; Ifediora, Nkechime; Dees, Mitchell; Mela, Angeliki; Dovas, Athanassios; Pereira, Brianna; Viswanathan, Ashwin; Mahajan, Aayushi; Humala, Nelson; Furnari, Julia; Kotidis, Corina; Haile, Hannah; Khoury, Nadine; Adapa, Arjun; Winans, Nathan J.; Argenziano, Michael G.; Sperring, Colin; Yoh, Nina; Lei, Liang; Gill, Brian J.; Sims, Peter; Grinband, Jack; Canoll, Peter D.; Bruce, Jeffrey N.
Convection-enhanced delivery of dexamethasone potently suppresses glioma-associated inflammation in a mechanistically distinct way from systemic drug delivery

经增强的右美托咪定对流输送可显著抑制胶质瘤相关的炎症，其机制与全身性药物输送不同。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Rolfe, Nathaniel; Dadario, Nicholas; Lei, Liang; Teasley, Damian; Ifediora, Nkechime; Chabot, Peter; Tang, Anthony; Amini, Misha; Khoury, Nadine; Viswanathan, Ashwin; Furnari, Julia; Kotidis, Corina; Stucke, Clara; Winans, Nathan; Yoh, Nina; Humala, Nelson; Mahajan, Aayushi; Bruce, Jeffrey; Canoll, Peter
HUMAN AND MOUSE PERITUMORAL SLICES DEMONSTRATE MTOR-DEPENDENT GABAERGIC NEURONAL DYSFUNCTION IN GLIOMA

人源和鼠源肿瘤周切片显示胶质瘤中存在mTOR依赖的GABA能神经元功能障碍

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Viswanathan, Ashwin; Conboy, Karen; Wu, Xiaoping; Merricks, Edward M.; Young, Serina B.; Pereira, Brianna; Dovas, Athanassios; Goldberg, Alexander R.; Mahajan, Aayushi; Humala, Nelson; Furnari, Julia L.; Stucke, Clara; Amini, Misha; Rolfe, Nathaniel; McKhann II, Guy M.; Bruce, Jeffrey N.; Schevon, Catherine A.; Canoll, Peter; Gill, Brian J. A.
Intraoperative 5-Aminolevulinic Acid (5ALA) fluorescence distinguishes cellular composition and immunogenicity in the infiltrating margin of Glioblastoma

术中5-氨基乙酰丙酸（5ALA）荧光可区分胶质母细胞瘤浸润边缘的细胞组成和免疫原性。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Khoury, Nadine; Dadario, Nicholas; Brand, Abby; Ifediora, Nkechime; Olsen, Timothy; Lei, Liang; Bell, Amelia; Yalcindag, Selin Ege; Amini, Misha; Viswanathan, Ashwin; Schonfeld, Elan; Yoh, Nina; Boyett, Deborah; Winans, Nathan; Argenziano, Michael; Sperring, Colin; Kahle, August; Mahajan, Aayushi; Furnari, Julia; Kotidis, Corina; Dees, James Mitchell; Xu, Grace; Pacella, Daniel; Teasley, Damian; Rolfe, Nathaniel; McKhann, Guy; Sisti, Michael; Gill, Brian; Sims, Peter; Canoll, Peter; Bruce, Jeffrey
PROMINENT GLIOMA CALCIUM TRANSIENTS CAN BE REPEATEDLY TRIGGERED BY STIMULUS-EVOKED NEURONAL ACTIVITY AND PURINERGIC SIGNALING

显著胶质瘤钙瞬变可被刺激诱发的神经元活动和嘌呤能信号反复触发。

NEURO-ONCOLOGY
IF13.4
2025-11-010
PRE
Pereira, Brianna; Lodgher, Fatema; Yagielski, Alexis J.; Dovas, Athanassios; Mela, Angeliki; Viswanathan, Ashwin; Goldberg, Alexander R.; Conboy, Karen; Humala, Nelson; Mahajan, Aayushi; Amini, Misha; Bruce, Jeffrey N.; Schevon, Catherine A.; Gill, Brian J. A.; Peterka, Darcy S.; Hillman, Elizabeth M. C.; Canoll, Peter
IDH1(R132H) inhibitors enhance the sensitivity of IDH1-mutant glioma to cysteine deprivation and ferroptosis

IDH1(R132H)抑制剂增强了IDH1突变型胶质瘤对半胱氨酸剥夺和铁死亡的敏感性。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Mela, Angeliki; Brand, Abby; Mahajan, Aayushi; Dovas, Athanassios; Humala, Nelson; Kanangat, Smriti; Kleinstein, Allison; Leskinen, Sandra; Nguyen, Trang T. T.; Gao, Qiuqiang; Upadhyayula, Pavan S.; Guo, Jia; Gill, Brian J. A.; Siegelin, Markus D.; Sims, Peter A.; Stockwell, Brent R.; Bruce, Jeffrey N.; Canoll, Peter
Glioma-induced alterations in excitatory neurons are reversed by mTOR inhibition

胶质瘤诱导的兴奋性神经元改变可通过mTOR抑制得到逆转

NEURON
IF15
2025-01-010
PRE
Goldberg, Alexander R.; Dovas, Athanassios; Torres, Daniela; Pereira, Brianna; Viswanathan, Ashwin; Das Sharma, Sohani; Mela, Angeliki; Merricks, Edward M.; Megino-Luque, Cristina; Mcinvale, Julie J.; Olabarria, Markel; Shokooh, Leila Abrishami; Zhao, Hanzhi T.; Chen, Cady; Kotidis, Corina; Calvaresi, Peter; Banu, Matei A.; Razavilar, Aida; Sudhakar, Tejaswi D.; Saxena, Ankita; Chokran, Cole; Humala, Nelson; Mahajan, Aayushi; Xu, Weihao; Metz, Jordan B.; Bushong, Eric A.; Boassa, Daniela; Ellisman, Mark H.; Hillman, Elizabeth M. C.; Hargus, Gunnar; Bravo-Cordero, Jose Javier; McKhann Ii, Guy M.; Gill, Brian J. A.; Rosenfeld, Steven S.; Schevon, Catherine A.; Bruce, Jeffrey N.; Sims, Peter A.; Peterka, Darcy S.; Canoll, Peter
CHEMOTHERAPY INDUCED IMMUNOGENIC RESPONSE IN GLIOMA AND IMPLICATIONS FOR THERAPEUTIC STRATEGIES
NEURO-ONCOLOGY
IF13.4
2024-11-110
PRE
Teasley, Damian; Dadario, Nicholas; Lei, Liang; Sperring, Colin; Khoury, Nadine; Rolfe, Nathaniel; Kristt, Melanie; Mela, Angeliki; Ifedoria, Nkechime; Kotidis, Corina; Zhao, Wenting; Furnari, Julia; Mahajan, Aayushi; Pereira, Brianna; Argenziano, Michael; Winans, Nathan; Yoh, Nina; Humala, Nelson; Dovas, Athanassios; Karan, Charles; Gill, Brian; Sims, Peter; Bruce, Jeffrey; Canoll, Peter
A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma
EMBO JOURNAL
IF8.3
2024-08-271
OAAI
Banu, Matei A.; Dovas, Athanassios; Argenziano, Michael G.; Zhao, Wenting; Sperring, Colin P.; Cuervo Grajal, Henar; Liu, Zhouzerui; Higgins, Dominique M. O.; Amini, Misha; Pereira, Brianna; Ye, Ling F.; Mahajan, Aayushi; Humala, Nelson; Furnari, Julia L.; Upadhyayula, Pavan S.; Zandkarimi, Fereshteh; Nguyen, Trang T. T.; Teasley, Damian; Wu, Peter B.; Hai, Li; Karan, Charles; Dowdy, Tyrone; Razavilar, Aida; Siegelin, Markus D.; Kitajewski, Jan; Larion, Mioara; Bruce, Jeffrey N.; Stockwell, Brent R.; Sims, Peter A.; Canoll, Peter
Multi-omic analysis of Huntington's disease reveals a compensatory astrocyte state
NATURE COMMUNICATIONS
IF15.7
2024-08-080
OAAI
Paryani, Fahad; Kwon, Ji-Sun; Ng, Christopher W.; Jakubiak, Kelly; Madden, Nacoya; Ofori, Kenneth; Tang, Alice; Lu, Hong; Xia, Shengnan; Li, Juncheng; Mahajan, Aayushi; Davidson, Shawn M.; Basile, Anna O.; Mchugh, Caitlin; Vonsattel, Jean Paul; Hickman, Richard; Zody, Michael C.; Housman, David E.; Goldman, James E.; Yoo, Andrew S.; Menon, Vilas; Al-Dalahmah, Osama
Xenografted human iPSC-derived neurons with the familial Alzheimer's disease APPV717I mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator
ACTA NEUROPATHOLOGICA
IF9.3
2024-06-250
OAAI
Qu, Wenhui; Lam, Matti; Mcinvale, Julie J.; Mares, Jason A.; Kwon, Sam; Humala, Nelson; Mahajan, Aayushi; Nguyen, Trang; Jakubiak, Kelly A.; Mun, Jeong-Yeon; Tedesco, Thomas G.; Al-Dalahmah, Osama; Hussaini, Syed A.; Sproul, Andrew A.; Siegelin, Markus D.; De Jager, Philip L.; Canoll, Peter; Menon, Vilas; Hargus, Gunnar
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
CELL STEM CELL
IF20.4
2024-05-011
OAAI
Al-Dalahmah, Osama; Lam, Matti; McInvale, Julie J.; Qu, Wenhui; Nguyen, Trang; Mun, Jeong-Yeon; Kwon, Sam; Ifediora, Nkechime; Mahajan, Aayushi; Humala, Nelson; Winters, Tristan; Angeles, Ellen; Jakubiak, Kelly A.; Kuhn, Rebekka; Kim, Yoon A.; De Rosa, Maria Caterina; Doege, Claudia A.; Paryani, Fahad; Flowers, Xena; Dovas, Athanassios; Mela, Angeliki; Lu, Hong; DeTure, Michael A.; Vonsattel, Jean Paul; Wszolek, Zbigniew K.; Dickson, Dennis W.; Kuhlmann, Tanja; Zaehres, Holm; Schoeler, Hans R.; Sproul, Andrew A.; Siegelin, Markus D.; De Jager, Philip L.; Goldman, James E.; Menon, Vilas; Canoll, Peter; Hargus, Gunnar
Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states
NATURE COMMUNICATIONS
IF15.7
2023-05-0422
OAAI
Al-Dalahmah, Osama; Argenziano, Michael G. G.; Kannan, Adithya; Mahajan, Aayushi; Furnari, Julia; Paryani, Fahad; Boyett, Deborah; Save, Akshay; Humala, Nelson; Khan, Fatima; Li, Juncheng; Lu, Hong; Sun, Yu; Tuddenham, John F. F.; Goldberg, Alexander R. R.; Dovas, Athanassios; Banu, Matei A. A.; Sudhakar, Tejaswi; Bush, Erin; Lassman, Andrew B. B.; McKhann, Guy M. M.; Gill, Brian J. A.; Youngerman, Brett; Sisti, Michael B. B.; Bruce, Jeffrey N. N.; Sims, Peter A. A.; Menon, Vilas; Canoll, Peter

研究方向

暂未获取到该数据
P
Peter Canoll
H 指数:77论文数:675被引数:2.2万
N
Nelson Humala
H 指数:19论文数:88被引数:3,062
J
Jeffrey N. Bruce
H 指数:77论文数:666被引数:2.2万
A
Angeliki Mela
H 指数:17论文数:76被引数:1,536
P
Peter A. Sims
H 指数:58论文数:354被引数:1.4万
J
Julia Furnari
H 指数:8论文数:61被引数:316
B
Brian Gill
H 指数:17论文数:68被引数:2,269
A
Athanassios Dovas
H 指数:25论文数:113被引数:3,222
B
Brianna Pereira
H 指数:7论文数:24被引数:305
M
Markus D. Siegelin
H 指数:48论文数:242被引数:7,024