未登录 Results of the phase IIa study to evaluate the efficacy and safety of rezivertinib (BPI-7711) for the first-line treatment of locally advanced or metastatic/recurrent NSCLC patients with EGFR mutation from a phase I/IIa study 来自I/IIa期研究的评估rezivetinib (BPI-7711) 一线治疗EGFR突变的局部晚期或转移性/复发性NSCLC患者的疗效和安全性的IIa期研究结果 Shi, Yuankai; Zhou, Jianying; Zhao, Yanqiu; Zhu, Bo; Zhang, Liangming; Li, Xingya; Fang, Jian; Shi, Jianhua; Zhuang, Zhixiang; Yang, Sheng; Wang, Donglin; Yu, Huiqing; Zhang, Longzhen; Zheng, Rongsheng; Greco, Michael; Wang, Tingting 分享 收藏
Discovery of PEGylated 6-Benzhydryl-4-amino-quinazolines as Peripherally Restricted CB1R Inverse Agonists Zhang, Yue-Mei; Greco, Michael; Le Blanc, Tonya; Lang, Wensheng; Kauffman, Jack; Masucci, John; Murray, William, V; Demarest, Keith; Macielag, Mark Joseph 分享 收藏
6-Benzhydryl-4-amino-quinolin-2-ones as Potent Cannabinoid Type 1 (CB1) Receptor Inverse Agonists and Chemical Modifications for Peripheral Selectivity Zhang, Yue-Mei; Greco, Michael N.; Macielag, Mark J.; Teleha, Christopher A.; DesJarlais, Renee L.; Tang, Yuting; Ho, George; Hou, Cuifen; Chen, Cailin; Zhao, Shuyuan; Kauffman, Jack; Camacho, Raul; Qi, Jenson; Murray, William; Demarest, Keith; Leonard, James 分享 收藏
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Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase Greco, Michael N.; Hawkins, Michael J.; Powell, Eugene T.; Almond, Harold R., Jr.; de Garavilla, Lawrence; Hall, Jeffrey; Minor, Lisa K.; Wang, Yuanping; Corcoran, Thomas W.; Di Cera, Enrico; Cantwell, Angelene M.; Savvides, Savvas N.; Damiano, Bruce P.; Maryanoff, Bruce E. 分享 收藏
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A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase -: Molecular mechanisms and anti-inflammatory activity in vivo de Garavilla, L; Greco, MN; Sukumar, N; Chen, ZW; Pineda, AO; Mathews, FS; Di Cera, E; Giardino, EC; Wells, GI; Haertlein, BJ; Kauffman, JA; Corcoran, TW; Derian, CK; Eckardt, AJ; Damiano, BP; Andrade-Gordon, P; Maryanoff, BE 分享 收藏
Structure-activity studies on anticonvulsant sugar sulfamates related to topiramate. Enhanced potency with cyclic sulfate derivatives. (vol 41, pg 1329, 1998) Maryanoff, BE; Costanzo, MJ; Nortey, SO; Greco, MN; Shank, RP; Schupsky, JJ; Ortegon, MP; Vaught, JFV 分享 收藏
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MACROCYCLIC PEPTIDE INHIBITORS OF SERINE PROTEASES - CONVERGENT TOTAL SYNTHESIS OF CYCLOTHEONAMIDES-A AND CYCLOTHEONAMIDES-B VIA A LATE-STAGE PRIMARY AMINE INTERMEDIATE - STUDY OF THROMBIN INHIBITION UNDER DIVERSE CONDITIONS (VOL 117, PG 1225, 1995) MARYANOFF, BE; GRECO, MN; ZHANG, HC; ANDRADEGORDON, P; KAUFFMAN, JA; NICOLAOU, KC; LIU, AJ; BRUNGS, PH 分享 收藏
Nonpeptide inhibitors of cathepsin G:: Optimization of a novel β-ketophosphonic acid lead by structure-based drug design Greco, MN; Hawkins, MJ; Powell, ET; Almond, HR; Corcoran, TW; de Garavilla, L; Kauffman, JA; Recacha, R; Chattopadhyay, D; Andrade-Gordon, P; Maryanoff, BE 分享 收藏
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