Nicolas L. Fawzi - Publications, H-index & Citations

Nicolas L. Fawzi

Brown University

49H指数

177论文数

1.3W被引数

收录论文 30

发表时间

Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain TDP-43 C末端结构域保守区域通过螺旋介导的多聚化的结构细节

Nature Communications

IF15.7

2025-11-26

OAAI

Azamat Rizuan; Jayakrishna Shenoy; Priyesh Mohanty; Patricia M. dos Passos; José F. Mercado Ortiz; Leanna Bai; Renjith Viswanathan; Julia Zaborowksy; Szu-Huan Wang; Victoria Johnson; Lohany D. Mamede; Amanda R. Titus; Yuna M. Ayala; Rodolfo Ghirlando; Jeetain Mittal; Nicolas L. Fawzi

Current practices in the study of biomolecular condensates: a community comment 生物分子凝聚体研究中的当前实践：一篇社区评论

Nature Communications

IF15.7

2025-08-19

OAAI

Simon Alberti; Paolo Arosio; Robert B. Best; Steven Boeynaems; Danfeng Cai; Rosana Collepardo-Guevara; Gregory L. Dignon; Rumiana Dimova; Shana Elbaum-Garfinkle; Nicolas L. Fawzi; Monika Fuxreiter; Amy S. Gladfelter; Alf Honigmann; Ankur Jain; Jerelle A. Joseph; Tuomas P. J. Knowles; Keren Lasker; Edward A. Lemke; Kresten Lindorff-Larsen; Reinhard Lipowsky; Jeetain Mittal; Samrat Mukhopadhyay; Sua Myong; Rohit V. Pappu; Karsten Rippe; Tatyana A. Shelkovnikova; Anthony G. Vecchiarelli; Susanne Wegmann; Huaiying Zhang; Mingjie Zhang; Chloe Zubieta; Markus Zweckstetter; Dorothee Dormann; Tanja Mittag

Small-molecule dissolution of stress granules by redox modulation benefits ALS models 通过氧化还原调节实现应激颗粒的小分子溶解，对ALS模型有益。

NATURE CHEMICAL BIOLOGY

IF13.7

2025-05-14

OAAI

Uechi, Hiroyuki; Sridharan, Sindhuja; Nijssen, Jik; Bilstein, Jessica; Iglesias-Artola, Juan M.; Kishigami, Satoshi; Casablancas-Antras, Virginia; Poser, Ina; Martinez, Eduardo J.; Boczek, Edgar; Wagner, Michael; Tomschke, Nadine; Domingues, Antonio M. de Jesus; Pal, Arun; Doeleman, Thom; Kour, Sukhleen; Anderson, Eric Nathaniel; Stein, Frank; Lee, Hyun O.; Zhang, Xiaojie; Fritsch, Anatol W.; Jahnel, Marcus; Fuersch, Julius; Murthy, Anastasia C.; Alberti, Simon; Bickle, Marc; Fawzi, Nicolas L.; Nadler, Andre; David, Della C.; Pandey, Udai B.; Hermann, Andreas; Stengel, Florian; Davis, Benjamin G.; Baldwin, Andrew J.; Savitski, Mikhail M.; Hyman, Anthony A.; Wheeler, Richard J.

Structure and interactions of prion-like domains in transcription factor Efg1 phase separation

BIOPHYSICAL JOURNAL

IF3.1

2024-06-01

PREAI

Wang, Szu-Huan; Zheng, Tongyin; Fawzi, Nicolas L.

A synergy between site- specific and transient interactions drives the phase separation of a disordered, low- complexity domain 位点特异性和瞬态相互作用之间的协同作用驱动无序，低复杂度域的相分离

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-08-14

OAAI

Mohanty, Priyesh; Shenoy, Jayakrishna; Rizuan, Azamat; Mercado-Ortiz, Jose F.; Fawzi, Nicolas L.; Mittal, Jeetain

Fibril formation and ordering of disordered FUS LC driven by hydrophobic interactions

NATURE CHEMISTRY

IF20.2

2023-05-25

OAAI

Maltseva, Daria; Chatterjee, Sayantan; Yu, Chun-Chieh; Brzezinski, Mateusz; Nagata, Yuki; Gonella, Grazia; Murthy, Anastasia C.; Stachowiak, Jeanne C.; Fawzi, Nicolas L.; Parekh, Sapun H.; Bonn, Mischa

Reversible Kinetic Trapping of FUS Biomolecular Condensates FUS生物分子缩合物的可逆动力学捕获

ADVANCED SCIENCE

IF14.1

2021-12-04

OAAI

Chatterjee, Sayantan; Kan, Yelena; Brzezinski, Mateusz; Koynov, Kaloian; Regy, Roshan Mammen; Murthy, Anastasia C.; Burke, Kathleen A.; Michels, Jasper J.; Mittal, Jeetain; Fawzi, Nicolas L.; Parekh, Sapun H.

Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-11-10

OAAI

Murthy, Anastasia C.; Tang, Wai Shing; Jovic, Nina; Janke, Abigail M.; Seo, Da Hee; Perdikari, Theodora Myrto; Mittal, Jeetain; Fawzi, Nicolas L.

Biophysical studies of phase separation integrating experimental and computational methods

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2021-10-01

OAAI

Fawzi, Nicolas L.; Parekh, Sapun H.; Mittal, Jeetain

The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation

JOURNAL OF CELL SCIENCE

IF3.6

2021-09-03

OAAI

Owen, Izzy; Yee, Debra; Wyne, Hala; Perdikari, Theodora Myrto; Johnson, Victoria; Smyth, Jeremy; Kortum, Robert; Fawzi, Nicolas L.; Shewmaker, Frank

CLAMP and Zelda function together to promote Drosophila zygotic genome activation

ELIFE

IF0

2021-08-03

OAAI

Duan, Jingyue; Rieder, Leila; Colonnetta, Megan M.; Huang, Annie; Mckenney, Mary; Watters, Scott; Deshpande, Girish; Jordan, William; Fawzi, Nicolas; Larschan, Erica

Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain LINE-1 ORF1蛋白的相分离由N端和卷曲螺旋结构域介导

BIOPHYSICAL JOURNAL

IF3.1

2021-06-01

OAAI

Newton, Jocelyn C.; Naik, Mandar T.; Li, Grace Y.; Murphy, Eileen L.; Fawzi, Nicolas L.; Sedivy, John M.; Jogl, Gerwald

A predictive coarse-grained model for position-specific effects of post-translational modifications

BIOPHYSICAL JOURNAL

IF3.1

2021-04-01

OAAI

Perdikari, Theodora Myrto; Jovic, Nina; Dignon, Gregory L.; Kim, Young C.; Fawzi, Nicolas L.; Mittal, Jeetain

Membrane bending by protein phase separation 蛋白质相分离的膜弯曲

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-09

127

OAAI

Yuan, Feng; Alimohamadi, Haleh; Bakka, Brandon; Trementozzi, Andrea N.; Day, Kasey J.; Fawzi, Nicolas L.; Rangamani, Padmini; Stachowiak, Jeanne C.

Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration 酪氨酸磷酸化调节hnRNPA2颗粒蛋白分配并减少神经变性

EMBO JOURNAL

IF8.3

2020-12-22

OAAI

Ryan, Veronica H.; Perdikari, Theodora M.; Naik, Mandar T.; Saueressig, Camillo F.; Lins, Jeremy; Dignon, Gregory L.; Mittal, Jeetain; Hart, Anne C.; Fawzi, Nicolas L.

SARS-CoV-2 nucleocapsid protein phase-separates with RNA and with human hnRNPs

EMBO JOURNAL

IF8.3

2020-12-04

198

OAAI

Perdikari, Theodora Myrto; Murthy, Anastasia C.; Ryan, Veronica H.; Watters, Scott; Naik, Mandar T.; Fawzi, Nicolas L.

Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation

NUCLEIC ACIDS RESEARCH

IF13.1

2020-09-01

OAAI

Ryan, Veronica H.; Watters, Scott; Amaya, Joshua; Khatiwada, Balabhadra; Venditti, Vincenzo; Naik, Mandar T.; Fawzi, Nicolas L.

TDP-43 α-helical structure tunes liquid-liquid phase separation and function TDP-43 α-螺旋结构调节液-液相分离和功能

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-03-04

243

OAAI

Conicella, Alexander E.; Dignon, Gregory L.; Zerze, Gul H.; Schmidt, Hermann Broder; D'Ordine, Alexandra M.; Kim, Young C.; Rohatgi, Rajat; Ayala, Yuna M.; Mittal, Jeetain; Fawzi, Nicolas L.

The (un)structural biology of biomolecular liquid-liquid phase separation using NMR spectroscopy

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-02-01

OAAI

Murthy, Anastasia C.; Fawzi, Nicolas L.

Molecular interactions underlying liquid-liquid phase separation of the FUS low-complexity domain

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2019-07-01

423

OAAI

Murthy, Anastasia C.; Dignon, Gregory L.; Kan, Yelena; Zerze, Gul H.; Parekh, Sapun H.; Mittal, Jeetain; Fawzi, Nicolas L.

研究方向