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H

Holger Greschik

klinikum der albert-ludwigs-universität freiburg
H指数:20
被引数:2,275

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KMT9 drives T cell exclusion and dysfunction by promoting PMN-MDSCs infiltration and ARG1 expression in prostate cancer

KMT9通过促进PMN-MDSCs浸润和ARG1表达，驱动T细胞排斥和功能障碍在前列腺癌中的作用

Molecular Cancer
IF33.9
2026-09-170
OAAI
Jon Peñarando; Dominica Willmann; Manuela Sum; Yanhan Jia; Christopher Berlin; Lukas M. Braun; Zihao Chen; Sylvia Urban; Manfred Jung; Delphine Duteil; Daniel Metzger; Christian Gratzke; Robert Zeiser; Holger Greschik; Roland Schüle; Eric Metzger
Molecular determinants for recognition of serotonylated chromatin

血清素化染色质的识别分子决定因素

NUCLEIC ACIDS RESEARCH
IF13.1
2025-07-220
OA
Pulido-Cortes, Laura; Gielingh, Hajo; Thijssen, Vito; Liu, Minglong; Yoshisada, Ryoji; Soares, Leonardo Romao; Nizamuddin, Sheikh; Friedrich, Florian; Greschik, Holger; Peng, Ling; Honorato, Rodrigo Vargas; Jung, Manfred; Bonvin, Alexandre M. J. J.; Biniossek, Martin L.; Schuele, Roland; Jongkees, Seino; van Ingen, Hugo; Timmers, H. Th Marc
Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity
NATURE COMMUNICATIONS
IF15.7
2024-01-022
OAAI
Wang, Sheng; Klein, Sebastian O.; Urban, Sylvia; Staudt, Maximilian; Barthes, Nicolas P. F.; Willmann, Dominica; Bacher, Johannes; Sum, Manuela; Bauer, Helena; Peng, Ling; Rennar, Georg A.; Gratzke, Christian; Schuele, Katrin M.; Zhang, Lin; Einsle, Oliver; Greschik, Holger; Macleod, Calum; Thomson, Christopher G.; Jung, Manfred; Metzger, Eric; Schuele, Roland
A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-09-2440
OAAI
Fagan, Vincent; Johansson, Catrine; Gileadi, Carina; Monteiro, Octovia; Dunford, James E.; Nibhani, Reshma; Philpott, Martin; Malzahn, Jessica; Wells, Graham; Faram, Ruth; Cribbs, Adam P.; Halidi, Nadia; Li, Fengling; Chau, Irene; Greschik, Holger; Velupillai, Srikannathasan; Allali-Hassani, Abdellah; Bennett, James; Christott, Thomas; Giroud, Charline; Lewis, Andrew M.; Huber, Kilian V. M.; Athanasou, Nick; Bountrat, Chas; Jung, Manfred; Schuele, Roland; Vedadi, Masoud; Arrowsmith, Cheryl; Xion, Yan; Jin, Jian; Fedorov, Oleg; Farnie, Gillian; Brennan, Paul E.; Oppermann, Udo
Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-07-0125
OAAI
Xiong, Yan; Greschik, Holger; Johansson, Catrine; Seifert, Ludwig; Bacher, Johannes; Park, Kwang-su; Babault, Nicolas; Martini, Michael; Fagan, Vincent; Li, Fengling; Chau, Irene; Christott, Thomas; Dilworth, David; Barsyte-Lovejoy, Dalia; Vedadi, Masoud; Arrowsmith, Cheryl H.; Brennan, Paul; Fedorov, Oleg; Jung, Manfred; Farnie, Gillian; Liu, Jing; Oppermann, Udo; Schuele, Roland; Jin, Jian
KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells
NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2019-05-0663
PREAI
Metzger, Eric; Wang, Sheng; Urban, Sylvia; Willmann, Dominica; Schmidt, Andreas; Offermann, Anne; Allen, Anita; Sum, Manuela; Obier, Nadine; Cottard, Felicie; Ulferts, Svenja; Preca, Bogdan-Tiberius; Hermann, Bianca; Maurer, Jochen; Greschik, Holger; Hornung, Veit; Einsle, Oliver; Perner, Sven; Imhof, Axel; Jung, Manfred; Schuele, Roland

研究方向

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R
Roland Schüle
H 指数:60论文数:331被引数:1.5万
M
Manfred Jung
H 指数:65论文数:469被引数:1.3万
E
Eric Metzger
H 指数:36论文数:119被引数:6,721
D
Dominica Willmann
H 指数:17论文数:59被引数:1,584
Y
Yan Xiong
H 指数:49论文数:218被引数:1.0万
U
Udo Oppermann
H 指数:77论文数:659被引数:2.1万
J
Jian Jin
H 指数:74论文数:494被引数:2.1万
T
Thomas Günther
H 指数:30论文数:87被引数:5,486
D
Dino Moras
H 指数:94论文数:582被引数:3.5万
M
Manuela Sum
H 指数:5论文数:21被引数:192