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孙伟光 封面图

孙伟光 (Weiguang Sun)

huazhong university of science and technology

30H指数
317论文数
2.8K被引数
收录论文 90
发表时间
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Remodeling the Host Immune Microenvironment in Carbapenem-Resistant Klebsiella pneumoniae: An Evidence-Graded Framework for Host-Directed Intervention重塑产碳青霉烯酶肺炎克雷伯菌宿主免疫微环境：基于证据分级的宿主导向干预框架
errInternational Journal of Antimicrobial Agents
IF4.6
err2026-09-06
err0
errOAAI
errXiaolin Liang; Junwei Wang; Chao Liu; Qingyuan Gao; Xiaoxia Gu; Weiguang Sun; Yan He
err分享
err收藏
Protein Kinase C Family: Structures, Biological Functions, Diseases, and Pharmaceutical InterventionsLi, Y.; Jiang, Y.; Hu, Z.; Yang, S.; Li, L.; Xiong, C.; Gao, Y.; Sun, W.; Zhang, Y. 蛋白激酶C家族：结构、生物学功能、疾病及药物干预。MedComm 2025, 6, e70474. [Google Scholar] [CrossRef]
errMEDCOMM
IF10.7
err2025-11-14
err1
errOAAI
errLi, Yongqi; Jiang, Yuhan; Hu, Zhengxi; Yang, Shenglan; Li, Longyin; Xiong, Chaohu; Gao, Ya; Sun, Weiguang; Zhang, Yonghui
err分享
err收藏
DeepSAT-Driven Discovery of Pimarane Diterpenoids from Arthrinium arundinis with Ulcerative Colitis Inhibitory Activity via NF-κB/MAPK PathwaysDeepSAT驱动的Arthrinium arundinis中具有溃疡性结肠炎抑制活性的松香烷二萜类化合物的发现（通过NF-κB/MAPK通路）
errOrganic Letters
IF5
err2025-10-14
err0
PREAI
errYu Chen; Qin Li; Yingjie Liu; Xinye Huang; Aimin Fu; Wenyi Zhang; Feiyi Wang; Mengsha Wei; Weiguang Sun; Chunmei Chen; Yonghui Zhang; Hucheng Zhu
err分享
err收藏
Highly Resilient Sodium Carboxymethyl Cellulose/Tuff Aerogel-Based Composite Phase Change Materials for Efficient Thermal Management高韧性羧甲基纤维素钠/火山灰气凝胶基复合相变材料，用于高效热管理
errACS Applied Energy Materials
IF5.5
err2025-10-13
err0
PREAI
errHangyu Hu; Chaoming Wang; Shuaiao Xie; Weiguang Sun
err分享
err收藏
Undulacin C, Ophiobolin-type sesterterpenoid with anti-autoimmune hepatitis activity from aspergillus undulatusUndulacin C，一种来自aspergillus undulatus的具有抗自身免疫性肝炎活性的Ophiobolin型倍半萜。
errBioorganic Chemistry
IF4.7
err2025-10-09
err0
PREAI
errYuyi Zheng; Yongqi Li; Qin Li; Ruping Fan; Liyan Sun; Weiguang Sun; Jie Cao; Chunmei Chen; Yonghui Zhang; Hucheng Zhu
err分享
err收藏
Undulanoids A−D: Unexpected sesterterpenoids as potent S100A8/A9 complex inhibitors for psoriasis treatmentUndulanoids A−D：作为银屑病治疗中强效S100A8/A9复合物抑制剂的意外倍半萜二醇类化合物
errActa Pharmaceutica Sinica B
IF14.6
err2025-09-11
err0
errOAAI
errYuyi Zheng; Xiaotian Zhang; Xiaoxia Gu; Yongqi Li; Qin Li; Yingli Zhu; Bingbing Dai; Yu Liang; Ruping Fan; Chunmei Chen; Weiguang Sun; Yonghui Zhang; Hucheng Zhu
err分享
err收藏
Structurally diverse polyketides with herbicidal activity from the fungus Aspergillus aculeatus.具有除草活性的结构多样性聚酮化合物，来源于真菌Aspergillus aculeatus。
errPhytochemistry
IF3.4
err2025-08-05
err0
PREAI
errFei Liu; Shanshan Hong; Xiaoxia Gu; Qian Zhang; Qin Li; Weiguang Sun; Chunmei Chen; Yonghui Zhang; Hucheng Zhu
err分享
err收藏
(±)-Talapyrones A−F: six pairs of dimeric polyketide enantiomers with unusual 6/6/6 and 6/6/6/5 ring systems from Talaromycesadpressus(±)-塔拉波因A−F：源自皱褶曲霉的六对具有特殊6/6/6和6/6/6/5环系的二聚聚酮对映异构体
errChinese Journal of Natural Medicines
IF4.9
err2025-08-01
err0
PREAI
errMeijia Zheng; Xinyi Zhao; Chenxi Zhou; Hong Liao; Qin Li; Yuling Lu; Bingbing Dai; Weiguang Sun; Ying Ye; Chunmei Chen; Yonghui Zhang; Hucheng Zhu
err分享
err收藏
Stelleroids A–C; Three Rearranged Guaiane Sesquiterpenoids with Caged Ring Systems from Stellera chamaejasmeStellaroids A–C; 三种来自狼毒(Stellera chamaejasme)的具笼状环系的重新排列的愈创木烷倍半萜类化合物
errOrganic Letters
IF5
err2025-07-11
err0
PREAI
errXue Gong; Xiaotian Zhang; Tao-Tao Yuan; Xing Sun; Zhengxi Hu; Jun-Cheng Su; Weiguang Sun; Luo-Sheng Wan
err分享
err收藏
Discovery of structurally diverse polyprenylated acylphloroglucinols with quorum sensing inhibitory activity from Hypericum seniawinii Maxim.从Hypericum seniawinii Maxim.中发现的具有群体感应抑制活性的结构多样的多聚prenyl化酰基高莲宁醇。
errNatural Products and Bioprospecting
IF4.9
err2025-06-19
err0
errOAAI
errYulin Duan; Xiaoxia Gu; Xincai Hao; Guosheng Cao; Weiguang Sun; Changxing Qi; Yonghui Zhang
err分享
err收藏
Discovery of natural CdnP inhibitors through structure-based virtual screening and molecular dynamics simulations基于结构的虚拟筛选和分子动力学模拟发现天然CdnP抑制剂
errMICROBIOLOGY SPECTRUM
IF3.8
err2025-06-03
err0
errOAAI
errGu, Xiaoxia; Xiong, Chaohu; Wang, Xinyu; Zhu, Hucheng; Sun, Weiguang; He, Yan; Zhang, Jinwen
err分享
err收藏
Bipoladisins A-G, Uncommon Sesterterpenoids with Three Types of Carbon Skeletons from Bipolaris maydis and Their Reversal Activity on Paclitaxel Resistance布极霉素A-G，来自Bipolaris maydis的三种碳骨架结构的罕见倍半萜类化合物及其对紫杉醇耐药性的逆转活性
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2025-05-21
err0
PREAI
errYong Shen; Qin Li; Nanjin Ding; Mengru Yu; Xiaoxia Gu; Weiguang Sun; Ying Tang; Chunmei Chen; Yonghui Zhang; Hucheng Zhu
err分享
err收藏
Asperstrins A-H: Epipolythiodioxopiperazines from the endophytic fungus Aspergillus nidulans
errPHYTOCHEMISTRY
IF3.4
err2025-05-14
err0
PREAI
errZhang, Jiajun; Dong, Jiaxin; Fu, Aimin; Sun, Weiguang; Chen, Chunmei; Li, Qin; Zhang, Yonghui; Zhu, Hucheng
err分享
err收藏
Aculeanoids A-D, the second 17- nor fusicoccane diterpenoids with immunosuppressive activity from Aspergillus aculeatus
errPHYTOCHEMISTRY
IF3.4
err2025-05-01
err0
PREAI
errLiu, Fei; Li, Qin; Li, Yongqi; Liao, Hong; Sun, Weiguang; Li, Jianguo; Chen, Chunmei; Zhang, Yonghui; Zhu, Hucheng
err分享
err收藏
Aspergixanthones L- T, nine undescribed prenylxanthone derivatives from Aspergillus stellatus
errPHYTOCHEMISTRY
IF3.4
err2025-05-01
err0
PREAI
errLiang, Yu; Chen, Xuanni; Li, Qin; Zhao, Ziming; Wang, Hao; Tong, Qingyi; Sun, Weiguang; Zhu, Hucheng; Lai, Yongji; Chen, Chunmei; Zhang, Yonghui
err分享
err收藏
Discovery of Indole Alkaloids Crienamides A and B from Penicillium citrinum by a Simulated MS/MS-Guided Molecular Network Strategy通过模拟MS/MS引导的分子网络策略从Penicillium citrinum中发现吲哚生物碱Crienamides A和B
errORGANIC LETTERS
IF5
err2025-04-02
err0
PREAI
errPeng, Yuanyang; Luo, Shang; Li, Qin; Li, Yongqi; Zhang, Jiale; Ding, Nanjin; Sun, Weiguang; Chen, Chunmei; Liu, Junjun; Ye, Ying; Zhu, Hucheng
err分享
err收藏
Design, synthesis, and biological evaluation of β-carboline derivatives as ABCB1 inhibitors for reversing multidrug resistance
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-04-01
err0
PREAI
errWang, Yuanyuan; Ding, Nanjin; Zhao, Yunpeng; Wang, Fengqing; Liu, Wen; Chen, Zhe; Sun, Weiguang; Gu, Lianghu; Zhang, Yonghui
err分享
err收藏
Shape-stabilized polyethylene glycol/tuff composite phase change materials for efficient battery thermal management
errJOURNAL OF MATERIALS SCIENCE
IF3.9
err2025-04-01
err0
PREAI
errHu, Hangyu; Sun, Weiguang; Wang, Chaoming; Zhang, Lei
err分享
err收藏
Design and synthesis of butyrolactone V derivatives and its anti-inflammatory activity analysis丁内酯V衍生物的设计、合成及其抗炎活性分析
errChinese Herbal Medicines
IF8.9
err2025-03-19
err0
errOAAI
errWen Liu; Biqiong Zhang; Zhengxi Hu; Si Yao; Yunpeng Zhao; Fengqing Wang; Yuanyuan Wang; Xinxin Yang; Jie Yin; Weiguang Sun; Qingyi Tong; Lianghu Gu; Yonghui Zhang
err分享
err收藏
Trichodenoids A and B, Two Skeletally Unprecedented Polyketides from Trichoderma reesei with Cardioprotective Effects against H2O2-Induced Injury
errJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
IF6.2
err2025-03-01
err0
PREAI
errJiang, Rui; Guo, Jiayi; Yang, Shenglan; Zeng, Hanxiao; Wei, Jiangchun; Jin, Xiaoqi; Zheng, Xinyu; Sun, Weiguang; Zhang, Yonghui; Hu, Zhengxi
err分享
err收藏

研究方向

天然药物活性评价、作用靶点反向虚拟筛选和机制研究基于蛋白质结构的药物设计与发现【教育与工作经历】创新药物筛选技术先导化合物筛选2021/09-2023/08，200万元，在研，主持2022/01-2025/12，55万，在研，主持组合生物合成构建新骨架人工产物基于机器学习的成药分子设计新骨架人工产物药效学评价2021/12-2026/11，100万元，在研，课题骨干螺环倍半萜银屑病治疗肿瘤坏死因子-α抑制剂concanavalin A-induced autoimmune hepatitis天然产物化学真菌次级代谢产物麦角甾醇聚醚加合物天然产物α-吡喃酮衍生物免疫抑制活性功能化倍半萜内生真菌具有TNF-α抑制活性的未描述核苷衍生物环B芳构化甾醇环戊噻吩相关吲哚生物碱神经保护活性急性肝损伤改善金线莲苷减轻酒精性肝损伤减少氧化应激抑制内质网应激调节AMPK依赖性自噬除草活性海洋真菌天然产物抗肿瘤活性研究口服活性小分子肿瘤坏死因子-α抑制剂发现环戊烷二萜抗炎活性海洋沉积物真菌倍半萜烯天然产物碳骨架生态毒理学环境安全植物毒性NiduterpenoidsSesterterpenoidsAspergillus nidulans倍半萜烯衍生物二萜PPAR-γ激动活性Alternaria brassicicola抗炎fusicoccane型二萜类化合物植物病原真菌Alternaria brassicicola呋喃萜二萜结构-稳定性关系IKKβ抑制剂单萜-莽草酸共轭杂萜螺环系统
合作学者
合作期刊
李亮 封面图
李亮 (L. Li)
H 指数: 181 · 论文数: 3.7K
刘洋 封面图
刘洋 (Yang Liu)
H 指数: 89 · 论文数: 3.4K
X
Xiao‐Nian Li
H 指数: 80 · 论文数: 1.6K
李华 封面图
李华 (Hua Li)
H 指数: 74 · 论文数: 1.4K
J
Jianguo Chen
H 指数: 66 · 论文数: 407
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