Malcolm F. G. Stevens - Publications, H-index & Citations

Malcolm F. G. Stevens

University of Nottingham

50H指数

339论文数

1.0W被引数

收录论文 64

发表时间

Discovery of new imidazotetrazinones with potential to overcome tumor resistance

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-09-01

OAAI

Summers, Helen S.; Lewis, William; Williams, Huw E. L.; Bradshaw, Tracey D.; Moody, Christopher J.; Stevens, Malcolm F. G.

Antitumour imidazotetrazines: past, present... and future?

RSC CHEMICAL BIOLOGY

IF3.1

2023-01-01

OAAI

Stevens, Malcolm F. G.; Wheelhouse, Richard T.

Chemosensitization of Temozolomide-Resistant Pediatric Diffuse Midline Glioma Using Potent Nanoencapsulated Forms of a N(3)-Propargyl Analogue

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2021-07-26

OAAI

Shargh, Vahid Heravi; Luckett, Jeni; Bouzinab, Kaouthar; Paisey, Stephen; Turyanska, Lyudmila; Singleton, William G. B.; Lowis, Stephen; Gershkovich, Pavel; Bradshaw, Tracey D.; Stevens, Malcolm F. G.; Bienemann, Alison; Coyle, Beth

Delivery of Temozolomide and N3-Propargyl Analog to Brain Tumors Using an Apoferritin Nanocage

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2020-02-19

OAAI

Bouzinab, Kaouthar; Summers, Helen S.; Stevens, Malcolm F. G.; Moody, Christopher J.; Thomas, Neil R.; Gershkovich, Pavel; Weston, Nicola; Ashford, Marianne B.; Bradshaw, Tracey D.; Turyanska, Lyudmila

C8-Substituted Imidazotetrazine Analogs Overcome Temozolomide Resistance by Inducing DNA Adducts and DNA Damage C8-Substituted咪唑四嗪类似物通过诱导DNA加合物和DNA损伤来克服替莫唑胺抗性

FRONTIERS IN ONCOLOGY

IF3.3

2019-06-11

OAAI

Yang, Zhikuan; Wei, Danping; Dai, Xiaoli; Stevens, Malcolm F. G.; Bradshaw, Tracey D.; Luo, Ying; Zhang, Jihong

Temozolomide analog PMX 465 downregulates MGMT expression in HCT116 colorectal carcinoma cells

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2018-03-25

OAAI

Yang, Zhikuan; Wei, Danping; Liu, Feifei; Liu, Jing; Wu, Xiaoming; Stevens, Malcolm F. G.; Bradshaw, Tracey D.; Luo, Ying; Zhang, Jihong

Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2015-11-01

PREAI

Stone, Erica L.; Citossi, Francesca; Singh, Rajinder; Kaur, Balvinder; Gaskell, Margaret; Farmer, Peter B.; Monks, Anne; Hose, Curtis; Stevens, Malcolm F. G.; Leong, Chee-Onn; Stocks, Michael; Kellam, Barrie; Marlow, Maria; Bradshaw, Tracey D.

Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences

CHEMICAL COMMUNICATIONS

IF4.2

2014-10-23

OAAI

Cousins, Alex R. O.; Ritson, Dougal; Sharma, Pallavi; Stevens, Malcolm F. G.; Moses, John E.; Searle, Mark S.

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

IF12.8

2014-10-06

OAAI

Rizzo, Angela; Iachettini, Sara; Zizza, Pasquale; Cingolani, Chiara; Porru, Manuela; Artuso, Simona; Stevens, Malcolm; Hummersone, Marc; Biroccio, Annamaria; Salvati, Erica; Leonetti, Carlo

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

IF12.8

2013-09-19

OAAI

Iachettini, Sara; Stevens, Malcolm F. G.; Frigerio, Mark; Hummersone, Marc G.; Hutchinson, Ian; Garner, Thomas P.; Searle, Mark S.; Wilson, David W.; Munde, Manoj; Nanjunda, Rupesh; D'Angelo, Carmen; Zizza, Pasquale; Rizzo, Angela; Cingolani, Chiara; De Cicco, Federica; Porru, Manuela; D'Incalci, Maurizio; Leonetti, Carlo; Biroccio, Annamaria; Salvati, Erica

Quinol derivatives as potential trypanocidal agents

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2012-02-01

OAAI

Capes, Amy; Patterson, Stephen; Wyllie, Susan; Hallyburton, Irene; Collie, Iain T.; McCarroll, Andrew J.; Stevens, Malcolm F. G.; Frearson, Julie A.; Wyatt, Paul G.; Fairlamb, Alan H.; Gilbert, Ian H.

CYP2S1 and CYP2W1 Mediate 2-(3,4-Dimethoxyphenyl)-5-Fluorobenzothiazole (GW-610, NSC 721648) Sensitivity in Breast and Colorectal Cancer Cells

MOLECULAR CANCER THERAPEUTICS

IF5.5

2011-10-09

OAAI

Tan, Boon Shing; Tiong, Kai Hung; Muruhadas, Ashwin; Randhawa, Nirmal; Choo, Heng Lungh; Bradshaw, Tracey D.; Stevens, Malcolm F. G.; Leong, Chee-Onn

DNA Damage Persistence as Determinant of Tumor Sensitivity to the Combination of Topo I Inhibitors and Telomere-Targeting Agents

CLINICAL CANCER RESEARCH

IF10.2

2011-04-14

OAAI

Biroccio, Annamaria; Porru, Manuela; Rizzo, Angela; Salvati, Erica; D'Angelo, Carmen; Orlandi, Augusto; Passeri, Daniela; Franceschin, Marco; Stevens, Malcolm F. G.; Gilson, Eric; Beretta, Giovanni; Zupi, Gabriella; Pisano, Claudio; Zunino, Franco; Leonetti, Carlo

Antitumor Quinol PMX464 Is a Cytocidal Anti-trypanosomal Inhibitor Targeting Trypanothione Metabolism

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-03-01

OAAI

Koenig, Janine; Wyllie, Susan; Wells, Geoffrey; Stevens, Malcolm F.; Wyatt, Paul G.; Fairlamb, Alan H.

Preliminary clinical experiences of Phortress: Putative role for c-MET inhibition in antitumor activity

MOLECULAR CANCER THERAPEUTICS

IF5.5

2009-12-01

PREAI

Bradshaw, Tracey D.; Stevens, Malcolm F. G.; Calvert, Hilary; Plummer, E. Ruth

Novel temozolomide analog may overcome MGMT and MMR

MOLECULAR CANCER THERAPEUTICS

IF5.5

2009-12-01

PREAI

Zhang, Jihong; Stevens, Malcolm F. G.; Kerschmeier, Paul; Hummersone, Marc; Laughton, Charles A.; Bradshaw, Tracey D.

Role of endoplasmic reticulum stress in mechanism of action of antitumor quinols

MOLECULAR CANCER THERAPEUTICS

IF5.5

2009-12-01

PREAI

Matthews, Charles S.; McCarroll, Andrew J.; Stevens, Malcolm F. G.; Monks, Anne; Bradshaw, Tracey D.

Carbene Reactivity of 4-Diazo-4H-imidazoles toward Nucleophiles and Aromatic Compounds

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2009-11-18

PREAI

Smith, Matthew R.; Blake, Alexander J.; Hayes, Christopher J.; Stevens, Malcolm F. G.; Moody, Christopher J.

Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway

NUCLEIC ACIDS RESEARCH

IF13.1

2009-07-13

158

OAAI

Rizzo, Angela; Salvati, Erica; Porru, Manuela; D'Angelo, Carmen; Stevens, Malcolm F.; D'Incalci, Maurizio; Leonetti, Carlo; Gilson, Eric; Zupi, Gabriella; Biroccio, Annamaria

2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole is a ligand and shows species-specific partial agonism of the aryl hydrocarbon receptor

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2009-05-01

PREAI

Bazzi, Rana; Bradshaw, Tracey D.; Rowlands, J. Craig; Stevens, Malcolm F. G.; Bell, David R.

研究方向