Edward A. Sausville - Publications, H-index & Citations

Edward A. Sausville

merck & company

101H指数

565论文数

4.0W被引数

收录论文 81

发表时间

Editor's Note: Antiangiogenic Properties of 17-(Dimethylaminoethylamino)-17-Demethoxygeldanamycin: An Orally Bioavailable Heat Shock Protein 90 Modulator (vol 10 pg 4813, 2004)

CLINICAL CANCER RESEARCH

IF10.2

2024-05-01

PREAI

Kaur, Gurmeet; Belotti, Dorina; Burger, Angelika M.; Fisher-Nielson, Kirsten; Borsotti, Patrizia; Riccardi, Elena; Thillainathan, Jagada; Hollingshead, Melinda; Sausville, Edward A.; Giavazzi, Raffaella

Phase 1 trial of navitoclax and sorafenib in patients with relapsed or refractory solid tumors with hepatocellular carcinoma expansion cohort

INVESTIGATIONAL NEW DRUGS

IF2.7

2024-01-25

PREAI

Emiloju, Oluwadunni E.; Yin, Jun; Koubek, Emily; Reid, Joel M.; Borad, Mitesh J.; Lou, Yanyan; Seetharam, Mahesh; Edelman, Martin J.; Sausville, Edward A.; Jiang, Yixing; Kaseb, Ahmed O.; Posey, James A.; Davis, Sarah L.; Gores, Gregory J.; Roberts, Lewis R.; Takebe, Naoko; Schwartz, Gary K.; Hendrickson, Andrea E. Wahner; Kaufmann, Scott H.; Adjei, Alex A.; Hubbard, Joleen M.; Costello, Brian A.

Treatment of CD19-positive mixed phenotype acute leukemia with blinatumomab

AMERICAN JOURNAL OF HEMATOLOGY

IF9.9

2018-11-25

OAAI

El Chaer, Firas; Ali, Omer M.; Sausville, Edward A.; Law, Jennie Y.; Lee, Seung Tae; Duong, Vu H.; Baer, Maria R.; Koka, Rima; Singh, Zeba N.; Wong, Jerry; Yared, Jean A.; Griffiths, Elizabeth A.; Emadi, Ashkan

Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor Veliparib (ABT-888) in Combination with Irinotecan in Patients with Advanced Solid Tumors

CLINICAL CANCER RESEARCH

IF10.2

2016-06-30

OAAI

LoRusso, Patricia M.; Li, Jing; Burger, Angelika; Heilbrun, Lance K.; Sausville, Edward A.; Boerner, Scott A.; Smith, Daryn; Pilat, Mary Jo; Zhang, Jie; Tolaney, Sara M.; Cleary, James M.; Chen, Alice P.; Rubinstein, Lawrence; Boerner, Julie L.; Bowditch, Adam; Cai, Dongpo; Bell, Tracy; Wolanski, Andrew; Marrero, Allison M.; Zhang, Yiping; Ji, Jiuping; Ferry-Galow, Katherine; Kinders, Robert J.; Parchment, Ralph E.; Shapiro, Geoffrey I.

Somatic mutation profile differences of driver mutations in 26 oncogenic lung cancer genes between African American and European American non-small cell lung cancer patients

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Stephens, Sarah H.; Fleming, Patrice J.; Mitchell, Braxton D.; Ambulos, Nicholas; Bailey-Wilson, Joan E.; Chang, Christy; Feliciano, Josephine L.; Sausville, Edward A.; Edelman, Martin J.

Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-07-13

OAAI

Heredia, Alonso; Le, Nhut; Gartenhaus, Ronald B.; Sausville, Edward; Medina-Moreno, Sandra; Zapata, Juan C.; Davis, Charles; Gallo, Robert C.; Redfield, Robert R.

First-in-human phase 1 study of filanesib (ARRY-520), a kinesin spindle protein inhibitor, in patients with advanced solid tumors

INVESTIGATIONAL NEW DRUGS

IF2.7

2015-02-17

PREAI

LoRusso, Patricia M.; Goncalves, Priscila H.; Casetta, Lindsay; Carter, Judith A.; Litwiler, Kevin; Roseberry, Dale; Rush, Selena; Schreiber, Jennifer; Simmons, Heidi M.; Ptaszynski, Mieke; Sausville, Edward A.

Disparities in Black and White Patients With Multiple Myeloma Referred for Autologous Hematopoietic Transplantation: A Single Center Study

CANCER

IF5.1

2014-12-02

OAAI

Bhatnagar, Vishal; Wu, Yin; Goloubeva, Olga G.; Ruehle, Kathleen T.; Milliron, Todd E.; Harris, Carolynn G.; Rapoport, Aaron P.; Yanovich, Saul; Sausville, Edward A.; Baer, Maria R.; Badros, Ashraf Z.

Use of Virtual High-Dose-Rate (HDR) Brachytherapy via Spatially Fractionated GRID Radiation Therapy (SFGRT) as Part of Neoadjuvant Therapy in Poor Prognosis, Bulky Sarcomas

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2014-09-01

PREAI

Snider, J. W., III; Francis, M.; Hanna, N.; Alexander, H.; Sausville, E.; Amin, P. P.; Regine, W. F.

Phase I study of UCN-01 and perifosine in patients with relapsed and refractory acute leukemias and high-risk myelodysplastic syndrome

INVESTIGATIONAL NEW DRUGS

IF2.7

2013-10-01

OAAI

Gojo, Ivana; Perl, Alexander; Luger, Selina; Baer, Maria R.; Norsworthy, Kelly J.; Bauer, Kenneth S.; Tidwell, Michael; Fleckinger, Stephanie; Carroll, Martin; Sausville, Edward A.

Phase 1 dose-escalation, pharmacokinetic, and cerebrospinal fluid distribution study of TAK-285, an investigational inhibitor of EGFR and HER2

INVESTIGATIONAL NEW DRUGS

IF2.7

2013-07-02

OAAI

LoRusso, Patricia; Venkatakrishnan, Karthik; Chiorean, E. Gabriela; Noe, Dennis; Wu, Jing-Tao; Sankoh, Serap; Corvez, Maria; Sausville, Edward A.

A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the O6-Methylguanine-DNA Methyltransferase Promoter

MOLECULAR CANCER THERAPEUTICS

IF5.5

2013-05-08

PREAI

Hochhauser, Daniel; Glynne-Jones, Rob; Potter, Vanessa; Gravalos, Cristina; Doyle, Thomas J.; Pathiraja, Kumudu; Zhang, Qing; Zhang, Ling; Sausville, Edward A.

Reducing Undesirable Hepatic Clearance of a Tumor-Targeted Vinca Alkaloid via Novel Saccharopeptidic Modifications

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2011-02-01

PREAI

Leamon, Christopher P.; Reddy, Joseph A.; Klein, Patrick J.; Vlahov, Iontcho R.; Dorton, Ryan; Bloomfield, Alicia; Nelson, Melissa; Westrick, Elaine; Parker, Nikki; Bruna, Kristen; Vetzel, Marilynn; Gehrke, Mark; Nicoson, Jeffrey S.; Messmann, Richard A.; LoRusso, Patricia M.; Sausville, Edward A.

Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of the Combination of Sorafenib and Tanespimycin

CLINICAL CANCER RESEARCH

IF10.2

2010-07-14

OAAI

Vaishampayan, Ulka N.; Burger, Angelika M.; Sausville, Edward A.; Heilbrun, Lance K.; Li, Jing; Horiba, M. Naomi; Egorin, Merrill J.; Ivy, Percy; Pacey, Simon; LoRusso, Patricia M.

Phase I study of XMT-1001, a novel water soluble camptothecin conjugate, given as an intravenous infusion once every three weeks to patients with advanced solid tumors

MOLECULAR CANCER THERAPEUTICS

IF5.5

2009-12-01

PREAI

Sausville, Edward A.; Garbo, Lawrence; Weiss, Glen J.; Shkolny, Dana; Yurkovetskiy, Alexander V.; Bethune, Claudette; Ramanathan, Ramesh K.; Fram, Robert J.

Entinostat: A novel class I isoform selective histone deacetylase inhibitor (HDACi) with unique pharmacological properties

MOLECULAR CANCER THERAPEUTICS

IF5.5

2009-12-01

PREAI

Ordentlich, Peter; Lee, Gloria; Kunkel, Lori; Sausville, Edward

Phospho-p70S6K/p85S6K and cdc2/cdk1 Are Novel Targets for Diffuse Large B-Cell Lymphoma Combination Therapy

CLINICAL CANCER RESEARCH

IF10.2

2009-02-27

OAAI

Zhao, Merry Y.; Auerbach, Aaron; D'Costa, Anisha M.; Rapoport, Aaron P.; Burger, Angelika M.; Sausville, Edward A.; Stass, Sanford A.; Jiang, Feng; Sands, Amy M.; Aguilera, Nadine; Zhao, X. Frank

Preclinical Studies of Vorinostat (Suberoylanilide Hydroxamic Acid) Combined with Cytosine Arabinoside and Etoposide for Treatment of Acute Leukemias

CLINICAL CANCER RESEARCH

IF10.2

2009-02-27

OAAI

Shiozawa, Ken; Nakanishi, Takeo; Tan, Ming; Fang, Hong-Bin; Wang, Wen-chyi; Edelman, Martin J.; Carlton, David; Gojo, Ivana; Sausville, Edward A.; Ross, Douglas D.

Targetable HPMA Copolymer-Aminohexylgeldanamycin Conjugates for Prostate Cancer Therapy

PHARMACEUTICAL RESEARCH

IF4.3

2009-02-19

OAAI

Borgman, Mark P.; Ray, Abhijit; Kolhatkar, Rohit B.; Sausville, Edward A.; Burger, Angelika M.; Ghandehari, Hamidreza

Cell microarray platform for anticancer drug development

DRUG DEVELOPMENT RESEARCH

IF4.2

2007-11-13

PREAI

Lee, Min-Jung; Chung, Eun Joo; Lee, Sunmin; Chung, Joon-Yong; Telford, William G.; Sausville, Edward A.; Gojo, Ivana; Karp, Judith E.; Gore, Steven D.; Kapoor, Veena; Kim, Yeong Sang; Kummar, Shivaani; Gutierrez, Martin; Hewitt, Stephen M.; Trepel, Jane B.

研究方向