Jun‐ichi Sawada - Publications, H-index & Citations

Jun‐ichi Sawada

national institute of health sciences - japan

52H指数

317论文数

8.9K被引数

收录论文 52

发表时间

Crystal structure of the motor domain of centromere-associated protein E in complex with a non-hydrolysable ATP analogue

FEBS LETTERS

IF3

2023-03-05

OAAI

Shibuya, Asuka; Suzuki, Akira; Ogo, Naohisa; Sawada, Jun-ichi; Asai, Akira; Yokoyama, Hideshi

Various effects of two types of kinesin-5 inhibitors on mitosis and cell proliferation

BIOCHEMICAL PHARMACOLOGY

IF5.6

2021-11-01

PREAI

Sawada, Jun-ichi; Matsuno, Kenji; Ogo, Naohisa; Asai, Akira

Design, synthesis, and evaluation of a novel prodrug, a S-trityl-L-cysteine derivative targeting kinesin spindle protein

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-04-01

PREAI

Fukai, Ryota; Ogo, Naohisa; Ichida, Taiki; Yamane, Masayoshi; Sawada, Jun-ichi; Miyoshi, Nao; Murakami, Hisashi; Asai, Akira

Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative

MOLECULAR PHARMACOLOGY

IF3

2019-11-01

OAAI

Sawada, Jun-ichi; Ishii, Hirosuke; Matsuno, Kenji; Sato, Masayuki; Suzuki, Yumiko; Asai, Akira

Investigating toxicity specific to adjuvanted vaccines

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2017-12-01

PREAI

Matsumoto, Mineo; Komatsu, Shin-ichi; Ikeda, Takanori; Shimomura, Kazuhiro; Watanabe, Kazuto; Hirabayashi, Keiji; Sawada, Jun-ichi; Maki, Kazushige; Shinoda, Kazutoshi; Fueki, Osamu; Onodera, Hiroshi

Fluorescent anticancer quinazolines as molecular probes for β-tubulin colchicine site competition assay and visualization of microtubules as intracellular targeting sites 荧光抗癌喹唑啉作为 β-微管蛋白的分子探针秋水仙碱位点竞争测定和微管作为细胞内靶向位点的可视化

DYES AND PIGMENTS

IF4.2

2017-10-01

PREAI

Suzuki, Yumiko; Sawada, Jun-ichi; Hibner, Paulina; Ishii, Hirosuke; Matsuno, Kenji; Sato, Masayuki; Witulski, Bernhard; Asai, Akira

Structure-Guided Design of Novel L-Cysteine Derivatives as Potent KSP Inhibitors

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2015-07-28

OAAI

Ogo, Naohisa; Ishikawa, Yoshinobu; Sawada, Jun-ichi; Matsuno, Kenji; Hashimoto, Akihiro; Asai, Akira

Novel cysteine derivatives for the next generation anticancer agents acting on

EUROPEAN JOURNAL OF CANCER

IF7.1

2014-11-01

PREAI

Ogo, N.; Sawada, J.; Ishikawa, Y.; Matsuno, K.; Hashimoto, A.; Asai, A.

Considerations for non-clinical safety studies of therapeutic peptide vaccines

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2014-10-01

PREAI

Matsumoto, Mineo; Komatsu, Shinichi; Tsuchimoto, Mayumi; Matsui, Hajime; Watanabe, Kazuto; Nakamura, Kazuichi; Amakasu, Kohei; Ito, Kanako; Fueki, Osamu; Sawada, Jun-ichi; Maki, Kazushige; Onodera, Hiroshi

Optimization of diaryl amine derivatives as kinesin spindle protein inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2014-06-01

OAAI

Takeuchi, Tomoki; Oishi, Shinya; Kaneda, Masato; Misu, Ryosuke; Ohno, Hiroaki; Sawada, Jun-ichi; Asai, Akira; Nakamura, Shinya; Nakanishi, Isao; Fujii, Nobutaka

Kinesin Spindle Protein Inhibitors with Diaryl Amine Scaffolds: Crystal Packing Analysis for Improved Aqueous Solubility 具有二芳基胺支架的驱动蛋白纺锤体蛋白抑制剂: 用于改善水溶性的晶体堆积分析

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2014-03-14

OAAI

Takeuchi, Tomoki; Oishi, Shinya; Kaneda, Masato; Ohno, Hiroaki; Nakamura, Shinya; Nakanishi, Isao; Yamane, Masayoshi; Sawada, Jun-ichi; Asai, Akira; Fujii, Nobutaka

Silk Gland Factor-2, Involved in Fibroin Gene Transcription, Consists of LIM Homeodomain, LIM-interacting, and Single-stranded DNA-binding Proteins

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-11-01

OAAI

Ohno, Kaoru; Sawada, Jun-ichi; Takiya, Shigeharu; Kimoto, Mai; Matsumoto, Akiko; Tsubota, Takuya; Uchino, Keiro; Hui, Chi-chung; Sezutsu, Hideki; Handa, Hiroshi; Suzuki, Yoshiaki

Genetic Variations of Orosomucoid Genes Associated with Serum Alpha-1-Acid Glycoprotein Level and the Pharmacokinetics of Paclitaxel in Japanese Cancer Patients

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2011-10-01

PREAI

Katori, Noriko; Sai, Kimie; Saito, Yoshiro; Fukushima-Uesaka, Hiromi; Kurose, Kouichi; Yomota, Chikako; Kawanishi, Toru; Nishimaki-Mogami, Tomoko; Naito, Mikihiko; Sawada, Jun-Ichi; Kunitoh, Hideo; Nokihara, Hiroshi; Sekine, Ikuo; Ohe, Yuichiro; Yoshida, Teruhiko; Matsumura, Yasuhiro; Saijo, Nagahiro; Yamamoto, Noboru; Okuda, Haruhiro; Tamura, Tomohide

Structure-Activity Relationships of Carboline and Carbazole Derivatives as a Novel Class of ATP-Competitive Kinesin Spindle Protein Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2011-06-07

PREAI

Takeuchi, Tomoki; Oishi, Shinya; Watanabe, Toshiaki; Ohno, Hiroaki; Sawada, Jun-ichi; Matsuno, Kenji; Asai, Akira; Asada, Naoya; Kitaura, Kazuo; Fujii, Nobutaka

S-trityl-L-cysteine derivative induces caspase-independent cell death in K562 human chronic myeloid leukemia cell line

CANCER LETTERS

IF10.1

2010-12-01

PREAI

Shimizu, Makiko; Ishii, Hirosuke; Ogo, Naohisa; Unno, Yuka; Matsuno, Kenji; Sawada, Jun-ichi; Akiyama, Yasuto; Asai, Akira

Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2010-07-09

OAAI

Sai, Kimie; Saito, Yoshiro; Tatewaki, Naoko; Hosokawa, Masakiyo; Kaniwa, Nahoko; Nishimaki-Mogami, Tomoko; Naito, Mikihiko; Sawada, Jun-ichi; Shirao, Kuniaki; Hamaguchi, Tetsuya; Yamamoto, Noboru; Kunitoh, Hideo; Tamura, Tomohide; Yamada, Yasuhide; Ohe, Yuichiro; Yoshida, Teruhiko; Minami, Hironobu; Ohtsu, Atsushi; Matsumura, Yasuhiro; Saijo, Nagahiro; Okuda, Haruhiro

Kinesin Spindle Protein (KSP) Inhibitors with 2,3-Fused Indole Scaffolds

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2010-06-03

PREAI

Oishi, Shinya; Watanabe, Toshiaki; Sawada, Jun-ichi; Asai, Akira; Ohno, Hiroaki; Fujii, Nobutaka

Binding of PDZ-RhoGEF to ATP-binding Cassette Transporter A1 (ABCA1) Induces Cholesterol Efflux through RhoA Activation and Prevention of Transporter Degradation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-05-01

OAAI

Okuhira, Keiichiro; Fitzgerald, Michael L.; Tamehiro, Norimasa; Ohoka, Nobumichi; Suzuki, Kazuhiro; Sawada, Jun-ichi; Naito, Mikihiko; Nishimaki-Mogami, Tomoko

Confirmation of a predicted lack of IgE binding to Cry3Bb1 from genetically modified (GM) crops

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2010-04-01

PREAI

Nakajima, Osamu; Koyano, Satoru; Akiyama, Hiroshi; Sawada, Jun-ichi; Teshima, Reiko

Survival Prediction for Pancreatic Cancer Patients Receiving Gemcitabine Treatment

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2010-04-01

OAAI

Matsubara, Junichi; Ono, Masaya; Honda, Kazufumi; Negishi, Ayako; Ueno, Hideki; Okusaka, Takuji; Furuse, Junji; Furuta, Koh; Sugiyama, Emiko; Saito, Yoshiro; Kaniwa, Nahoko; Sawada, Junichi; Shoji, Ayako; Sakuma, Tomohiro; Chiba, Tsutomu; Saijo, Nagahiro; Hirohashi, Setsuo; Yamada, Tesshi

研究方向