Le Xu - Publications, H-index & Citations

徐

徐乐 (Le Xu)

faculty of animal science and technology

33H指数

145论文数

4.8K被引数

收录论文 45

发表时间

Assessing the Probiotic Properties and safety of Limosilactobacillus reuteri LP4 Isolated from Apis cerana Based on Whole Genome and Phenotype Analyses 基于全基因组及表型分析评估从Apis cerana中分离的Limiosilactobacillus reuteri LP4的益生菌特性与安全性

Probiotics and Antimicrobial Proteins

IF4.4

2025-08-02

PREAI

Le Xu; Pingping Fang; Mingkui Lv; Shiyu Chen; Chen Liu; Sifan Wang; Jiqin Li; Kun Dong; Qiuye Lin; Zhenhui Cao

A method for active deception jamming discrimination based on frequency response

CHINESE JOURNAL OF AERONAUTICS

IF5.7

2024-06-01

OAAI

Wei, Wenbin; Peng, Ruihui; Dong, Yunlong; Sun, Dianxing; Xu, Le; Wang, Guohong

Design, synthesis, and biological activity of novel semicarbazones as potent Ryanodine receptorl inhibitors of Alzheimer's disease

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2021-01-01

PREAI

Dai, Baozhu; Ma, Xingxing; Tang, Yadong; Xu, Le; Guo, Su; Chen, Xinyan; Lu, Shitong; Wang, Guangjie; Liu, Yajing

Single-channel properties of skeletal muscle ryanodine receptor pore Δ4923FF4924 in two brothers with a lethal form of fetal akinesia

CELL CALCIUM

IF4

2020-05-01

OAAI

Xu, Le; Harms, Frederike L.; Chirasani, Venkat R.; Pasek, Daniel A.; Kortuem, Fanny; Meinecke, Peter; Dokholyan, Nikolay, V; Kutsche, Kerstin; Meissner, Gerhard

Discovery of 4-piperazinyl-2-aminopyrimidine derivatives as dual inhibitors of JAK2 and FLT3

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-11-01

PREAI

Li, Yingxiu; Ye, Tianyu; Xu, Le; Dong, Yuhong; Luo, Yong; Wang, Chu; Han, Yufei; Chen, Ke; Qin, Mingze; Liu, Yajing; Zhao, Yanfang

A central core disease mutation in the Ca2+-binding site of skeletal muscle ryanodine receptor impairs single-channel regulation

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2019-08-01

OAAI

Chirasani, Venkat R.; Xu, Le; Addis, Hannah G.; Pasek, Daniel A.; Dokholyan, Nikolay, V; Meissner, Gerhard; Yamaguchi, Naohiro

Mutation Analysis of the Calcium Binding Site of Skeletal Muscle Ryanodine Receptor Calcium Release Channel

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Chirasani, Venkat R.; Xu, Le; Carter, Jordan S.; Addis, Hannah G.; Pasek, Daniel A.; Dokholyan, Nikolay V.; Meissner, Gerhard; Yamaguchi, Naohiro

Ca2+-mediated activation of the skeletal-muscle ryanodine receptor ion channel Ca2介导的骨骼肌ryanodine受体离子通道的激活

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-12-01

OAAI

Xu, Le; Chirasani, Venkat R.; Carter, Jordan S.; Pasek, Daniel A.; Dokholyan, Nikolay V.; Yamaguchi, Naohiro; Meissner, Gerhard

Synthesis, Design, and Structure-Activity Relationship of the Pyrimidone Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase

MOLECULES

IF4.6

2018-05-24

OAAI

Xu, Le; Li, Wenjie; Diao, Yanyan; Sun, Hongxia; Li, Honglin; Zhu, Lili; Zhou, Hongchang; Zhao, Zhenjiang

G4941K substitution in the pore-lining S6 helix of the skeletal muscle ryanodine receptor increases RyR1 sensitivity to cytosolic and luminal Ca2+

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-02-01

OAAI

Xu, Le; Mowrey, David D.; Chirasani, Venkat R.; Wang, Ying; Pasek, Daniel A.; Dokholyan, Nikolay V.; Meissner, Gerhard

Two EF-hand motifs in ryanodine receptor calcium release channels contribute to isoform-specific regulation by calmodulin ryanodine受体钙释放通道中的两个EF手基序有助于钙调蛋白对亚型的特异性调节

CELL CALCIUM

IF4

2017-09-01

OAAI

Xu, Le; Gomez, Angela C.; Pasek, Daniel A.; Meissner, Gerhard; Yamaguchi, Naohiro

Ion-pulling simulations provide insights into the mechanisms of channel opening of the skeletal muscle ryanodine receptor

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-08-01

OAAI

Mowrey, David D.; Xu, Le; Mei, Yingwu; Pasek, Daniel A.; Meissner, Gerhard; Dokholyan, Nikolay V.

Channel Gating Dependence on Pore Lining Helix Glycine Residues in Skeletal Muscle Ryanodine Receptor

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-07-01

OAAI

Mei, Yingwu; Xu, Le; Mowrey, David D.; Giraldez, Raul Mendez; Wang, Ying; Pasek, Daniel A.; Dokholyan, Nikolay V.; Meissner, Gerhard

Selecting Ions by Size in a Calcium Channel: The Ryanodine Receptor Case Study

BIOPHYSICAL JOURNAL

IF3.1

2014-11-01

OAAI

Gillespie, Dirk; Xu, Le; Meissner, Gerhard

Pore Dynamics and Conductance of RyR1 Transmembrane Domain

BIOPHYSICAL JOURNAL

IF3.1

2014-06-01

OAAI

Shirvanyants, David; Ramachandran, Srinivas; Mei, Yingwu; Xu, Le; Meissner, Gerhard; Dokholyan, Nikolay V.

Structural Determinants of Skeletal Muscle Ryanodine Receptor Gating

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-03-01

OAAI

Ramachandran, Srinivas; Chakraborty, Asima; Xu, Le; Mei, Yingwu; Samso, Montserrat; Dokholyan, Nikolay V.; Meissner, Gerhard

Stabilization of the Skeletal Muscle Ryanodine Receptor Ion Channel-FKBP12 Complex by the 1,4-Benzothiazepine Derivative S107

BIOPHYSICAL JOURNAL

IF3.1

2013-01-01

OAAI

Mei, Yingwu; Xu, Le; Kramer, Henning H.; Tomberlin, Ginger H.; Townsend, Claire; Meissner, Gerhard

Cardiac Hypertrophy Associated with Impaired Regulation of Type2 Ryanodine Receptor Calcium Channel by Calmodulin and S100A1

BIOPHYSICAL JOURNAL

IF3.1

2013-01-01

OAAI

Yamaguchi, Naohiro; Chakraborty, Asima; Huang, Tai-Qin; Xu, Le; Gomez, Angela C.; Pasek, Daniel A.; Meissner, Gerhard

Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2011-05-01

OAAI

Yamaguchi, Naohiro; Prosser, Benjamin L.; Ghassemi, Farshid; Xu, Le; Pasek, Daniel A.; Eu, Jerry P.; Hernandez-Ochoa, Erick O.; Cannon, Brian R.; Wilder, Paul T.; Lovering, Richard M.; Weber, David; Melzer, Werner; Schneider, Martin F.; Meissner, Gerhard

Muscle weakness in Ryr1I4895T/WT knock-in mice as a result of reduced ryanodine receptor Ca2+ ion permeation and release from the sarcoplasmic reticulum

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2010-12-13

OAAI

Loy, Ryan E.; Orynbayev, Murat; Xu, Le; Andronache, Zoita; Apostol, Simona; Zvaritch, Elena; MacLennan, David H.; Meissner, Gerhard; Melzer, Werner; Dirksen, Robert T.

研究方向