未登录 Structure-activity relationship profiling of N-substituted 8-trifluoromethyl-9H-purin-6-amines as mitochondrial protonophores N-取代的8-三氟甲基-9H-嘌呤-6-胺类化合物作为线粒体质子载体的构效关系分析 Krinos, Emily L.; Fields, Rei J.; DeLuca, Isabella M.; Foutz, Mary A.; Li, Catherine; Hargett, Stefan R.; Beretta, Martina; Zhou, Mingyan; Shrestha, Riya; Gwinn, Reilly K.; Byrne, Frances L.; Hoehn, Kyle L.; Santos, Webster L. 分享 收藏
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Assessment of Spinster homologue 2 (Spns2)-dependent transport of sphingosine-1-phosphate as a therapeutic target 评估Spns2依赖的鞘氨醇-1-磷酸转运作为治疗靶点 Kharel, Yugesh; Huang, Tao; Dunnavant, Kyle; Foster, Daniel; Souza, George M. P. R.; Nimchuk, Katherine E.; Merchak, Andrea R.; Pavelec, Caitlin M.; Juskiewicz, Zuzanna J.; Alexander, Simon S.; Gaultier, Alban; Abbott, Stephen B. G.; Shin, Jung-Bum; Isakson, Brant E.; Xu, Wehao; Leitinger, Norbert; Santos, Webster L.; Lynch, Kevin R. 分享 收藏
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Design, synthesis, and biological evaluation of imidazo[4,5-b]pyridine mitochondrial uncouplers for the treatment of metabolic dysfunction-associated steatohepatitis (MASH) Salamoun, Joseph M.; Krinos, Emily L.; Foutz, Mary A.; Hargett, Stefan R.; Beretta, Martina; Shrestha, Riya; Hoehn, Kyle L.; Santos, Webster L. 分享 收藏
Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4-b]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Associated Steatohepatitis Foutz, Mary A.; Krinos, Emily L.; Beretta, Martina; Hargett, Stefan R.; Shrestha, Riya; Murray, Jacob H.; Duerre, Ethan; Salamoun, Joseph M.; Mccarter, Katrina; Shah, Divya P.; Hoehn, Kyle L.; Santos, Webster L. 分享 收藏
Beneficial effects of MGL-3196 and BAM15 combination in a mouse model of fatty liver disease Zhou, Mingyan; Li, Catherine; Byrne, Frances L.; Vancuylenburg, Calum S.; Olzomer, Ellen M.; Hargreaves, Adam; Wu, Lindsay E.; Shackel, Nicholas A.; Santos, Webster L.; Hoehn, Kyle L. 分享 收藏
Deficiency of the sphingosine-1-phosphate (S1P) transporter Mfsd2b protects the heart against hypertension-induced cardiac remodeling by suppressing the L-type-Ca2+ channel Duse, Dragos Andrei; Schroeder, Nathalie Hannelore; Srivastava, Tanu; Benkhoff, Marcel; Vogt, Jens; Nowak, Melissa Kim; Funk, Florian; Semleit, Nina; Wollnitzke, Philipp; Erkens, Ralf; Koetter, Sebastian; Meuth, Sven Guenther; Keul, Petra; Santos, Webster; Polzin, Amin; Kelm, Malte; Krueger, Martina; Schmitt, Joachim; Levkau, Bodo 分享 收藏
Chemo-, Regio-, and Stereoselective cis-Hydroboration of 1,3-Enynes: Copper-Catalyzed Access to (Z,Z)- and (Z,E)-2-Boryl-1,3-dienes Buchbinder, Nicklas W.; Nguyen, Long H.; Beck, Owen N.; Bage, Andrew D.; Slebodnick, Carla; Santos, Webster L. 分享 收藏
Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors Foster, Daniel J.; Dunnavant, Kyle; Shrader, Christopher W.; LoPresti, Marion; Seay, Sarah; Kharel, Yugesh; Brown, Anne M.; Huang, Tao; Lynch, Kevin R.; Santos, Webster L. 分享 收藏
Phosphine-catalyzed 1,2-cis-diboration of 1,3-butadiynes Li, Weipeng; Ricker, Robert; Chan, Ka Lok; Lau, Pak Fung; Buchbinder, Nicklas W.; Krebs, Johannes; Friedrich, Alexandra; Lin, Zhenyang; Santos, Webster L.; Radius, Udo; Marder, Todd B. 分享 收藏
Design, Synthesis, and Antifungal Activity of 3-Substituted-2(5H)-Oxaboroles Campbell, Rose; Buchbinder, Nicklas W.; Szwetkowski, Connor; Zhu, Yumeng; Piedl, Karla; Truong, Mindy; Matson, John B.; Santos, Webster L.; Mevers, Emily 分享 收藏
Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice Chen, Sing-Young; Telfser, Aiden J.; Olzomer, Ellen M.; Vancuylenberg, Calum S.; Zhou, Mingyan; Beretta, Martina; Li, Catherine; Alexopoulos, Stephanie J.; Turner, Nigel; Byrne, Frances L.; Santos, Webster L.; Hoehn, Kyle L. 分享 收藏
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Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice Beretta, Martina; Dai, Yumin; Olzomer, Ellen M.; Vancuylenburg, Calum S.; Santiago-Rivera, Jose A.; Philp, Ashleigh M.; Hargett, Stefan R.; Li, Keyong; Shah, Divya P.; Chen, Sing-Young; Alexopoulos, Stephanie J.; Li, Catherine; Harris, Thurl E.; Lee, Brendan; Wathier, Michel; Cermak, Jennifer M.; Tucker, Simon P.; Turner, Nigel; Bayliss, Douglas A.; Philp, Andrew; Byrne, Frances L.; Santos, Webster L.; Hoehn, Kyle L. 分享 收藏
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Oxadiazolopyridine Derivatives as Efficacious Mitochondrial Uncouplers in the Prevention of Diet-Induced Obesity Murray, Jacob H.; Burgio, Ariel L.; Beretta, Martina; Hargett, Stefan R.; Harris, Thurl E.; Olzomer, Ellen; Grams, R. Justin; Garcia, Christopher J.; Li, Catherine; Salamoun, Joseph M.; Hoehn, Kyle L.; Santos, Webster L. 分享 收藏
Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice 在db/db小鼠中通过卡路里限制和线粒体解偶联来靶向负能量平衡 Chen, Sing -Young; Beretta, Martina; Olzomer, Ellen M.; Shah, Divya P.; Wong, Derek Y. H.; Alexopoulos, Stephanie J.; Aleksovska, Isabella; Salamoun, Joseph M.; Garcia, Christopher J.; Cochran, Blake J.; Rye, Kerry-Anne; Smith, Greg C.; Byrne, Frances L.; Morris, Margaret J.; Santos, Webster L.; Cantley, James; Hoehn, Kyle L. 分享 收藏
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