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A

Alan Nadin

GlaxoSmithKline

29H指数
94论文数
4.1K被引数
收录论文 15
发表时间
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A Turing Test for Molecular Generators
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-09-21
err19
PREAI
errBush, Jacob T.; Pogany, Peter; Pickett, Stephen D.; Barker, Mike; Baxter, Andrew; Campos, Sebastien; Cooper, Anthony W. J.; Hirst, David; Inglis, Graham; Nadin, Alan; Patel, Vipulkumar K.; Poole, Darren; Pritchard, John; Washio, Yoshiaki; White, Gemma; Green, Darren V. S.
err分享
err收藏
Free-Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of N-Methylation for PI3Kδ Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2019-10-24
err7
PREAI
errBarnes, Lydia; Blaber, Hollie; Brooks, David T. K.; Byers, Lewis; Buckley, Daniel; Byron, Zoe C.; Chilvers, Richard G.; Cochrane, Liam; Cooney, Edward; Damian, Heather A.; Francis, Luke; He, Daniel Fu; Grace, Jack M. J.; Green, Harley J.; Hogarth, Edmund J. P.; Jusu, Leyla; Killalea, C. Elizabeth; King, Oliver; Lambert, Joseph; Lee, Zoe J.; Lima, Nuria S.; Long, Christina L.; Mackinnon, May-Li; Mahdy, Shusha; Matthews-Wright, Jolyon; Millward, Makenzie J.; Meehan, Matthew F.; Merrett, Christopher; Morrison, Lisa; Parke, Hal R. I.; Payne, Charlotte; Payne, Lawrence; Pike, Craig; Seal, Alexander; Senior, Aaron J.; Smith, Keenan M.; Stanelyte, Kamile; Stillibrand, Joe; Szpara, Rachel; Taday, Freya F. H.; Threadgould, Antony M.; Trainor, Rohan J.; Waters, Jordan; Williams, Oliver; Wong, Carrie K. W.; Wood, Katherine; Barton, Nick; Gruszka, Anna; Henley, Zoe; Rowedder, James E.; Cookson, Rosa; Jones, Katherine L.; Nadin, Alan; Smith, Ian E.; Macdonald, Simon J. F.; Nortcliffe, Andrew
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In Vivo Imaging of Small Molecular Weight Peptides for Targeted Renal Drug Delivery: A Study in Normal and Polycystic Kidney Diseased Mice
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2019-09-01
err11
errOAAI
errLenhard, Stephen C.; McAlexander, Allen; Virtue, Anthony; Fieles, William; Skedzielewski, Tina; Rambo, Mary; Han Trinh; Cheng, Shih-Hsun; Hong, Hyundae; Isidro-Llobet, Albert; Nadin, Alan; Geske, Robert; Klein, Jean-Louis; Lee, Dennis; Jucker, Beat M.; Hu, Erding
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Malonylation of GAPDH is an inflammatory signal in macrophages
errNATURE COMMUNICATIONS
IF15.7
err2019-01-18
err152
errOAAI
errGalvan-Pena, Silvia; Carroll, Richard G.; Newman, Carla; Hinchy, Elizabeth C.; Palsson-McDermott, Eva; Robinson, Elektra K.; Covarrubias, Sergio; Nadin, Alan; James, Andrew M.; Haneklaus, Moritz; Carpenter, Susan; Kelly, Vincent P.; Murphy, Michael P.; Modis, Louise K.; O'Neill, Luke A.
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Discovery of Novel PI3-Kinase δ Specific Inhibitors for the Treatment of Rheumatoid Arthritis: Taming CYP3A4 Time-Dependent Inhibition
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2012-06-11
err68
PREAI
errSafina, Brian S.; Baker, Stewart; Baumgardner, Matt; Blaney, Paul M.; Chan, Bryan K.; Chen, Yung-Hsiang; Cartwright, Matthew W.; Castanedo, Georgette; Chabot, Christine; Cheguillaume, Arnaud J.; Goldsmith, Paul; Goldstein, David M.; Goyal, Bindu; Hancox, Timothy; Handa, Raj K.; Lyer, Pravin S.; Kaur, Jasmit; Kondru, Rama; Kenny, Jane R.; Krintel, Sussie L.; Li, Jun; Lesnick, John; Lucas, Matthew C.; Lewis, Cristina; Mukadam, Sophie; Murray, Jeremy; Nadin, Alan J.; Nonomiya, Jim; Padilla, Fernando; Palmer, Wylie S.; Pang, Jodie; Pegg, Neil; Price, Steve; Reif, Karin; Salphati, Laurent; Savy, Pascal A.; Seward, Eileen M.; Shuttleworth, Stephen; Sohal, Sukhjit; Sweeney, Zachary K.; Tay, Suzanne; Tivitmahaisoon, Parcharee; Waszkowycz, Bohdan; Wei, Binqing; Yue, Qin; Zhang, Chenghong; Sutherlin, Daniel P.
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Lead-Oriented Synthesis: A New Opportunity for Synthetic Chemistry
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2012-01-03
err356
PREAI
errNadin, Alan; Hattotuwagama, Channa; Churcher, Ian
err分享
err收藏
SYNTHESIS OF ZARAGOZIC ACID A/SQUALESTATIN S1扎拉戈酸A/角鲨烯S1的合成
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2006-01-20
err105
PREAI
errNICOLAOU, KC; YUE, EW; LAGRECA, S; NADIN, A; YANG, Z; LERESCHE, JE; TSURI, T; NANIWA, Y; DERICCARDIS, F
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Quantitative measurement of changes in amyloid-β(40) in the rat brain and cerebrospinal fluid following treatment with the γ-secretase inhibitor LY-411575 [N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide]
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2005-05-01
err115
PREAI
errBest, JD; Jay, MT; Otu, F; Ma, J; Nadin, A; Ellis, S; Lewis, HD; Pattison, C; Reilly, M; Harrison, T; Shearman, MS; Williamson, TL; Atack, JR
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Selected non-steroidal anti-inflammatory drugs and their derivatives target γ-secretase at a novel site -: Evidence for an allosteric mechanism
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2004-10-01
err193
errOAAI
errBeher, D; Clarke, EE; Wrigley, JDJ; Martin, ACL; Nadin, A; Churcher, I; Shearman, MS
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New synthesis of 1,3-dihydro-1,4-benzodiazepin-2(2H)-ones and 3-amino-1,3-dihydro-1,4-benzodiazepin-2(2H)-ones:: Pd-catalyzed cross-coupling of imidoyl chlorides with organoboronic acids
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2003-03-07
err61
PREAI
errNadin, A; López, JMS; Owens, AP; Howells, DM; Talbot, AC; Harrison, T
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Synthesis and conformational dynamics of tricyclic pyridones containing a fused seven-membered ring
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2002-11-20
err40
PREAI
errGibson, KR; Hitzel, L; Mortishire-Smith, RJ; Gerhard, U; Jelley, RA; Reeve, AJ; Rowley, M; Nadin, A; Owens, AP
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γ-Secretase:: characterization and implication for Alzheimer disease therapy
errNEUROBIOLOGY OF AGING
IF3.5
err2002-11-01
err35
PREAI
errXu, M; Lai, MT; Huang, Q; DiMuzio-Mower, J; Castro, JL; Harrison, T; Nadin, A; Neduvelil, JG; Shearman, MS; Shafer, JA; Gardell, SJ; Li, JM
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7-MEMBERED LACTAMS AS CONSTRAINTS FOR AMIDE SELF-RECOGNITION
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2002-05-01
err28
PREAI
errNADIN, A; DERRER, S; MCGEARY, RP; GOODMAN, JM; RAITHBY, PR; HOLMES, AB
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err收藏
Pharmacological knock-down of the presenilin 1 heterodimer by a novel γ-secretase inhibitor -: Implications for presenilin biology
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2001-11-01
err96
errOAAI
errBeher, D; Wrigley, JDJ; Nadin, A; Evin, G; Masters, CL; Harrison, T; Castro, JL; Shearman, MS
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err收藏
An olefin metathesis based strategy for the construction of the JKL, OPQ, and UVW ring systems of maitotoxin
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err1996-10-23
err121
PREAI
errNicolaou, KC; Postema, MHD; Yue, EW; Nadin, A
err分享
err收藏

研究方向

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H 指数: 113 · 论文数: 941
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