未登录 Cyclin D1 determines mitochondrial function in vivo Sakamaki, Toshiyuki; Casimiro, Mathew C.; Ju, Xiaoming; Quong, Andrew A.; Katiyar, Sanjay; Liu, Manran; Jiao, Xuanmao; Li, Anping; Zhang, Xueping; Lu, Yinan; Wang, Chenguang; Byers, Stephen; Nicholson, Robert; Link, Todd; Shemluck, Melvin; Yang, Jianguo; Fricke, Stanley T.; Novikoff, Phyllis M.; Papanikolaou, Aletandros; Arnold, Andrew; Albanese, Christopher; Pestell, Richard 分享 收藏
Heregulin β1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells (vol 9, R50, 2007) Hutcheson, Iain R.; Knowlden, Janice M.; Hiscox, Steve E.; Barrow, Denise; Gee, Julia M. W.; Robertson, John F.; Ellis, Ian O.; Nicholson, Robert I. 分享 收藏
Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer Yang, Jun; AlTahan, Alaa; Jones, Dylan T.; Buffa, Francesca M.; Bridges, Esther; Interiano, Rodrigo B.; Qu, Chunxu; Vogt, Nathan; Li, Ji-Liang; Baban, Dilair; Ragoussis, Jiannis; Nicholson, Robert; Davidoff, Andrew M.; Harris, Adrian L. 分享 收藏
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Nuclear β-catenin negativity predicts for late relapse in ER plus , tamoxifen-treated breast cancer Hiscox, Stephen; Smith, Chris; Nicholson, Robert I.; Gee, Julia; Harris, Adrian; Bliss, Judith; Kalaizak, Eleftheria; Sestak, Ivana; Dowsett, Mitch; Cuzick, Jack; Ellis, Ian; Barrett-Lee, Peter 分享 收藏
Reprogramming of the ERRα and ERα Target Gene Landscape Triggers Tamoxifen Resistance in Breast Cancer Thewes, Verena; Simon, Ronald; Schroeter, Petra; Schlotter, Magdalena; Anzeneder, Tobias; Buettner, Reinhard; Benes, Vladimir; Sauter, Guido; Burwinkel, Barbara; Nicholson, Robert I.; Sinn, Hans-Peter; Schneeweiss, Andreas; Deuschle, Ulrich; Zapatka, Marc; Heck, Stefanie; Lichter, Peter 分享 收藏
Workshop Report: Crystal City V-Quantitative Bioanalytical Method Validation and Implementation: The 2013 Revised FDA Guidance Booth, Brian; Arnold, Mark E.; DeSilva, Binodh; Amaravadi, Lakshmi; Dudal, Sherri; Fluhler, Eric; Gorovits, Boris; Haidar, Sam H.; Kadavil, John; Lowes, Steve; Nicholson, Robert; Rock, Marie; Skelly, Michael; Stevenson, Lauren; Subramaniam, Sriram; Weiner, Russell; Woolf, Eric 分享 收藏
Elevated Src kinase activity attenuates Tamoxifen response in vitro and is associated with poor prognosis clinically Morgan, Liam; Gee, Julia; Pumford, Sara; Farrow, Lynne; Finlay, Pauline; Robertson, John; Ellis, Ian; Kawakatsu, Hisaaki; Nicholson, Robert; Hiscox, Stephen 分享 收藏
Increased Ret signalling and impact of vandetanib in acquired tamoxifen resistant breast cancer Gee, Julia M.; Goddard, Lindy; Mottram, Huw J.; Burmi, Rajpal S.; Pumford, Sara L.; Dutkowski, Carol M.; Barrow, Denise; Hutcheson, Iain R.; Nicholson, Robert I.; Ellis, Ian O.; Elvin, Paul 分享 收藏
Method Transfer, Partial Validation, and Cross Validation: Recommendations for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team Briggs, R. J.; Nicholson, R.; Vazvaei, F.; Busch, J.; Mabuchi, M.; Mahesh, K. S.; Brudny-Kloeppel, M.; Weng, N.; Galvinas, P. A. R.; Duchene, P.; Hu, Pei; Abbott, R. W. 分享 收藏
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BCL-2 Hypermethylation Is a Potential Biomarker of Sensitivity to Antimitotic Chemotherapy in Endocrine-Resistant Breast Cancer Stone, Andrew; Cowley, Mark J.; Valdes-Mora, Fatima; McCloy, Rachael A.; Sergio, C. Marcelo; Gallego-Ortega, David; Caldon, C. Elizabeth; Ormandy, Christopher J.; Biankin, Andrew V.; Gee, Julia M. W.; Nicholson, Robert I.; Print, Cristin G.; Clark, Susan J.; Musgrove, Elizabeth A. 分享 收藏
Global characterization of signalling networks associated with tamoxifen resistance in breast cancer Browne, Brigid C.; Hochgrafe, Falko; Wu, Jianmin; Millar, Ewan K. A.; Barraclough, Jane; Stone, Andrew; McCloy, Rachael A.; Lee, Christine S.; Roberts, Caroline; Ali, Naveid A.; Boulghourjian, Alice; Schmich, Fabian; Linding, Rune; Farrow, Lynn; Gee, Julia M. W.; Nicholson, Robert I.; O'Toole, Sandra A.; Sutherland, Robert L.; Musgrove, Elizabeth A.; Butt, Alison J.; Daly, Roger J. 分享 收藏
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Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan CD44的过表达伴随着MCF7细胞对他莫昔芬的获得性耐药性,并增强了它们对基质因子,调蛋白和透明质酸的敏感性。 Hiscox, Stephen; Baruha, Bedanta; Smith, Chris; Bellerby, Rebecca; Goddard, Lindy; Jordan, Nicola; Poghosyan, Zaruhi; Nicholson, Robert I.; Barrett-Lee, Peter; Gee, Julia 分享 收藏
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Dose-dependent change in biomarkers during neoadjuvant endocrine therapy with fulvestrant: results from NEWEST, a randomized Phase II study Kuter, Irene; Gee, Julia M. W.; Hegg, Roberto; Singer, Christian F.; Badwe, Rajendra A.; Lowe, Elizabeth S.; Emeribe, Ugochi A.; Anderson, Elizabeth; Sapunar, Francisco; Finlay, Pauline; Nicholson, Robert I.; Bines, Jose; Harbeck, Nadia 分享 收藏