未登录ATRN-119, a Novel Macrocyclic ATR Inhibitor, in Patients with Advanced Solid Malignancies: A Phase 1/2a Trial (ABOYA-119)
Mahipal, A.; LoRusso, P.; Schneider, R.; Miller, C.; Stenehjem, D.; Gullbo, J.; Brown, E.; Carleton, M.; Mirza, N.; Simpkins, F. .png)
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收藏First-in-human dose-expansion study of NBF-006, a novel investigational siRNA targeting GSTP, in patients with KRAS-mutated non-small cell lung cancerBazhenova, Lyudmila; Mamdani, Hirva; Chiappori, Alberto; Spira, Alexander; Iams, Wade; Tolcher, Anthony; Barve, Minal; Gabayan, Afshin; Vandross, Andrae; Cina, Cima; Cohen-Arazi, Yael; Albaugh, Zachary; Huynh, Annie; Gullbo, Joachim; Zabludoff, Sonya 分享 收藏 First-in-human phase 1/2a trial of a macrocyclic ATR inhibitor (ATRN-119) in patients with advanced solid tumorsSimpkins, Fiona; Mahipal, Amit; LoRusso, Patricia; Schneider, Reva; Miller, Crystal; Stenehjem, David; Brown, Eric J.; Carleton, Mike; Gullbo, Joachim; Mirza, Nadeem Q. 分享 收藏 First-in-human dose-expansion study of NBF-006, a novel investigational siRNA targeting GSTP, in patients with KRAS-mutated non-small cell lung cancerMamdani, Hirva; Chiappori, Alberto; Bazhenova, Lyudmila; Spira, Alexander; Iams, Wade; Barve, Minal; Tolcher, Anthony W.; Gabayan, Eli; Vandross, Andrae; Huynh, Annie; Cohen-Arazi, Yael; Albaugh, Zachary; Gullbo, Joachim; Zabludoff, Sonya 分享 收藏 分享 收藏 Melflufen for relapsed and refractory multiple myelomaMelflufen治疗复发和难治性多发性骨髓瘤Oriol, Albert; Larocca, Alessandra; Leleu, Xavier; Hajek, Roman; Hassoun, Hani; Rodriguez-Otero, Paula; Paner, Agne; Schjesvold, Fredrik H.; Gullbo, Joachim; Richardson, Paul G. 分享 收藏 Melflufen: A Peptide-Drug Conjugate for the Treatment of Multiple MyelomaMateos, Maria-Victoria; Blade, Joan; Bringhen, Sara; Ocio, Enrique M.; Efebera, Yvonne; Pour, Ludek; Gay, Francesca; Sonneveld, Pieter; Gullbo, Joachim; Richardson, Paul G. 分享 收藏 Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamideByrgazov, Konstantin; Anderson, Claes; Salzer, Benjamin; Bozsaky, Eva; Larsson, Rolf; Gullbo, Joachim; Lehner, Manfred; Lehmann, Fredrik; Slipicevic, Ana; Kager, Leo; Fryknaes, Marten; Taschner-Mandl, Sabine 分享 收藏 Phase 1 study of the protein deubiquitinase inhibitor VLX1570 in patients with relapsed and/or refractory multiple myelomaRowinsky, Eric K.; Paner, Agne; Berdeja, Jesus G.; Paba-Prada, Claudia; Venugopal, Parameswaran; Porkka, Kimmo; Gullbo, Joachim; Linder, Stig; Loskog, Angelica; Richardson, Paul G.; Landgren, Ola 分享 收藏 分享 收藏 Iron chelators target both proliferating and quiescent cancer cellsFryknas, Marten; Zhang, Xiaonan; Bremberg, Ulf; Senkowski, Wojciech; Olofsson, Maria Hagg; Brandt, Peter; Persson, Ingmar; D'Arcy, Padraig; Gullbo, Joachim; Nygren, Peter; Schughart, Leoni Kunz; Linder, Stig; Larsson, Rolf 分享 收藏 分享 收藏 The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells (vol 6, 26979, 2016)Wang, Xin; Mazurkiewicz, Magdalena; Hillert, Ellin-Kristina; Olofsson, Maria Hagg; Pierrou, Stefan; Hillertz, Per; Gullbo, Joachim; Selvaraju, Karthik; Paulus, Aneel; Akhtar, Sharoon; Bossler, Felicitas; Khan, Asher Chanan; Linder, Stig; D'Arcy, Padraig 分享 收藏 The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cellsWang, Xin; Mazurkiewicz, Magdalena; Hillert, Ellin-Kristina; Olofsson, Maria Hagg; Pierrou, Stefan; Hillertz, Per; Gullbo, Joachim; Selvaraju, Karthik; Paulus, Aneel; Akhtar, Sharoon; Bossler, Felicitas; Khan, Asher Chanan; Linder, Stig; D'Arcy, Padraig 分享 收藏 分享 收藏 First-in-human, phase I/IIa clinical study of the peptidase potentiated alkylator melflufen administered every three weeks to patients with advanced solid tumor malignancies每三周向晚期实体瘤恶性肿瘤患者服用肽酶增强烷化剂melflufen的首次人体I/IIa期临床研究Berglund, Ake; Ullen, Anders; Lisyanskaya, Alla; Orlov, Sergey; Hagberg, Hans; Tholander, Bengt; Lewensohn, Rolf; Nygren, Peter; Spira, Jack; Harmenberg, Johan; Jerling, Markus; Alvfors, Carina; Ringbom, Magnus; Nordstrom, Eva; Soderlind, Karin; Gullbo, Joachim 分享 收藏 分享 收藏 APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cellsAPR-246克服了卵巢癌细胞对顺铂和阿霉素的耐药性Mohell, N.; Alfredsson, J.; Fransson, A.; Uustalu, M.; Bystrom, S.; Gullbo, J.; Hallberg, A.; Bykov, V. J. N.; Bjorklund, U.; Wiman, K. G. 分享 收藏 分享 收藏 Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemiaEriksson, A.; Osterroos, A.; Hassan, S.; Gullbo, J.; Rickardson, L.; Jarvius, M.; Nygren, P.; Fryknas, M.; Hoglund, M.; Larsson, R. 分享 收藏 
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