Harma Ellens - Publications, H-index & Citations

Harma Ellens

GlaxoSmithKline

36H指数

82论文数

5.0K被引数

收录论文 13

发表时间

Hepatobiliary Disposition of Atovaquone: A Case of Mechanistically Unusual Biliary Clearance

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2018-07-01

OAAI

Patel, Mitesh; Johnson, Marta; Sychterz, Caroline J.; Lewis, Gareth J.; Watson, Cory; Ellens, Harma; Polli, Joseph W.; Zamek-Gliszczynski, Maciej J.

Mechanistic kinetic modeling generates system-independent P-glycoprotein mediated transport elementary rate constants for inhibition and, in combination with 3D SIM microscopy, elucidates the importance of microvilli morphology on P-glycoprotein mediated efflux activity

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2018-06-07

PREAI

Ellens, Harma; Meng, Zhou; Le Marchand, Sylvain J.; Bentz, Joe

The Importance of Villous Physiology and Morphology in Mechanistic Physiologically-Based Pharmacokinetic Models

PHARMACEUTICAL RESEARCH

IF4.3

2013-08-30

PREAI

Chen, Emile P.; Tai, Guoying; Ellens, Harma

Optimizing the in vitro and clinical assessment of drug interaction risk by understanding co-medications in patient populations

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2013-04-16

PREAI

Bloomer, Jackie; Derimanov, Geo; Dumont, Etienne; Ellens, Harma; Matheny, Christopher

ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2013-02-25

189

OAAI

Zamek-Gliszczynski, M. J.; Lee, C. A.; Poirier, A.; Bentz, J.; Chu, X.; Ellens, H.; Ishikawa, T.; Jamei, M.; Kavass, J. C.; Nagar, S.; Pang, K. S.; Korzekwa, K.; Swaan, P. W.; Taub, M. E.; Zhao, P.; Galetin, A.

Preclinical Strategy to Reduce Clinical Hepatotoxicity Using in Vitro Bioactivation Data for >200 Compounds

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2012-09-19

105

PREAI

Sakatis, Melanie Z.; Reese, Melinda J.; Harrell, Andrew W.; Taylor, Maxine A.; Baines, Ian A.; Chen, Liangfu; Bloomer, Jackie C.; Yang, Eric Y.; Ellens, Harma M.; Ambroso, Jeffrey L.; Lovatt, Cerys A.; Ayrton, Andrew D.; Clarke, Stephen E.

Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism

BRITISH JOURNAL OF CANCER

IF6.8

2010-04-13

111

OAAI

Xu, C-F; Reck, B. H.; Xue, Z.; Huang, L.; Baker, K. L.; Chen, M.; Chen, E. P.; Ellens, H. E.; Mooser, V. E.; Cardon, L. R.; Spraggs, C. F.; Pandite, L.

The steady-state Michaelis-Menten analysis of P-glycoprotein mediated transport through a confluent cell monolayer cannot predict the correct Michaelis constant Km

PHARMACEUTICAL RESEARCH

IF4.3

2005-09-22

PREAI

Bentz, J; Tran, TT; Polli, JW; Ayrton, A; Ellens, H

The elementary mass action rate constants of P-gp transport for a confluent monolayer of MDCKII-hMDR1 cells

BIOPHYSICAL JOURNAL

IF3.1

2005-01-01

OAAI

Tran, TT; Mittal, A; Aldinger, T; Polli, JW; Ayrton, A; Ellens, H; Bentz, J