Pierre‐Alain Carrupt - Publications, H-index & Citations

Pierre‐Alain Carrupt

University of Lausanne

66H指数

497论文数

1.5W被引数

收录论文 116

发表时间

Zebrafish bioassay-guided isolation of antiseizure compounds from the Cameroonian medicinal plant Cyperus articulatus L 斑马鱼生物测定指导的喀麦隆药用植物Cyperus articulatus L的抗癫痫药物隔离

PHYTOMEDICINE

IF8.3

2020-04-01

PREAI

Brillatz, Theo; Jacmin, Maxime; Queiroz, Emerson Ferreira; Marcourt, Laurence; Slacanin, Ivan; Petit, Charlotte; Carrupt, Pierre-Alain; Bum, Elisabeth Ngo; Herrling, Paul; Crawford, Alexander D.; Wolfender, Jean-Luc

HDM-PAMPA to predict gastrointestinal absorption, binding percentage, equilibrium and kinetics constants with human serum albumin and using 2 end-point measurements

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2017-01-01

PREAI

Bujard, Alban; Petit, Charlotte; Carrupt, Pierre-Alain; Rudaz, Serge; Schappler, Julie

Human sirtuins: Structures and flexibility

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2016-12-01

OAAI

Sacconnay, Lionel; Carrupt, Pierre-Alain; Nurisso, Alessandra

A Rational Approach for the Identification of Non-Hydroxamate HDAC6-Selective Inhibitors

SCIENTIFIC REPORTS

IF3.9

2016-07-12

OAAI

Goracci, Laura; Deschamps, Nathalie; Randazzo, Giuseppe Marco; Petit, Charlotte; Passos, Carolina Dos Santos; Carrupt, Pierre-Alain; Simoes-Pires, Claudia; Nurisso, Alessandra

Limits of rapid log P determination methods for highly lipophilic and flexible compounds

ANALYTICA CHIMICA ACTA

IF6

2016-04-01

PREAI

Martel, Sophie; Begnaud, Frederic; Schuler, William; Gillerat, Fabrice; Oberhauser, Nils; Nurisso, Alessandra; Carrupt, Pierre-Alain

5-Benzylidene-hydantoin is a new scaffold for SIRT inhibition: From virtual screening to activity assays

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2016-03-01

PREAI

Sacconnay, Lionel; Ryckewaert, Lucie; Randazzo, Giuseppe Marco; Petit, Charlotte; Passos, Carolina Dos Santos; Jachno, Jelena; Michailoviene, Vilma; Zubriene, Asta; Matulis, Daumantas; Carrupt, Pierre-Alain; Simoes-Pires, Claudia Avello; Nurisso, Alessandra

Pharmacophore-based discovery of inhibitors of a novel drug/proton antiporter in human brain endothelial hCMEC/D3 cell line

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2015-10-13

OAAI

Chapy, Helene; Goracci, Laura; Vayer, Philippe; Parmentier, Yannick; Carrupt, Pierre-Alain; Decleves, Xavier; Scherrmann, Jean-Michel; Cisternino, Salvatore; Cruciani, Gabriele

Modification of a PAMPA model to predict passive gastrointestinal absorption and plasma protein binding

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2015-09-01

PREAI

Bujard, Alban; Voirol, Herve; Carrupt, Pierre-Alain; Schappler, Julie

Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-07-09

OAAI

Farina, Roberta; Pisani, Leonardo; Catto, Marco; Nicolotti, Orazio; Gadaleta, Domenico; Denora, Nunzio; Soto-Otero, Ramon; Mendez-Alvarez, Estefania; Passos, Carolina S.; Muncipinto, Giovanni; Altomare, Cosimo D.; Nurisso, Alessandra; Carrupt, Pierre-Alain; Carotti, Angelo

How the flexibility of human histone deacetylases influences ligand binding: an overview

DRUG DISCOVERY TODAY

IF7.5

2015-06-01

PREAI

Deschamps, Nathalie; Simoes-Pires, Claudia Avello; Carrupt, Pierre-Alain; Nurisso, Alessandra

Inhibition screening method of microsomal UGTs using the cocktail approach

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2015-04-01

PREAI

Gradinaru, Julieta; Romand, Stephanie; Geiser, Laurent; Carrupt, Pierre-Alain; Spaggiari, Dany; Rudaz, Serge

Retention time prediction for dereplication of natural products (CxHyOz) in LC-MS metabolite profiling

PHYTOCHEMISTRY

IF3.4

2014-12-01

PREAI

Eugster, Philippe J.; Boccard, Julien; Debrus, Benjamin; Breant, Lise; Wolfender, Jean-Luc; Martel, Sophie; Carrupt, Pierre-Alain

cIEF for rapid pKa determination of small molecules: A proof of concept

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2014-10-01

PREAI

Romand, Stephanie; Schappler, Julie.; Veuthey, Jean-Luc; Carrupt, Pierre-Alain; Martel, Sophie

Study of Leaf Metabolome Modifications Induced by UV-C Radiations in Representative Vitis, Cissus and Cannabis Species by LC-MS Based Metabolomics and Antioxidant Assays

MOLECULES

IF4.6

2014-09-05

OAAI

Marti, Guillaume; Schnee, Sylvain; Andrey, Yannis; Simoes-Pires, Claudia; Carrupt, Pierre-Alain; Wolfender, Jean-Luc; Gindro, Katia

Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux 通过GSH外排，抗性MRP1-overexpressing细胞对黄酮类化合物和衍生物的间接敏感性

BIOCHEMICAL PHARMACOLOGY

IF5.6

2014-08-01

PREAI

Lorendeau, Doriane; Dury, Lauriane; Genoux-Bastide, Estelle; Lecerf-Schmidt, Florine; Simoes-Pires, Claudia; Carrupt, Pierre-Alain; Terreux, Raphael; Magnard, Sandrine; Di Pietro, Attilio; Boumendjel, Ahcene; Baubichon-Cortay, Helene

Modeling the Met Form of Human Tyrosinase: A Refined and Hydrated Pocket for Antagonist Design

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2014-05-14

PREAI

Favre, Elisabeth; Daina, Antoine; Carrupt, Pierre-Alain; Nurisso, Alessandra

MLP Tools: a PyMOL plugin for using the molecular lipophilicity potential in computer-aided drug design

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2014-04-29

PREAI

Oberhauser, Nils; Nurisso, Alessandra; Carrupt, Pierre-Alain

Computational Studies on Sirtuins from Trypanosoma cruzi: Structures, Conformations and Interactions with Phytochemicals

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2014-02-13

OAAI

Sacconnay, Lionel; Angleviel, Melissa; Randazzo, Giuseppe Marco; Queiroz, Marcos Marcal Ferreira; Queiroz, Emerson Ferreira; Wolfender, Jean-Luc; Carrupt, Pierre-Alain; Nurisso, Alessandra

Isolation and biological activity of compounds from Garcinia preussii

PHARMACEUTICAL BIOLOGY

IF4.8

2014-02-07

OAAI

Messi, Bernadette Biloa; Ho, Raimana; Lannang, Alain Meli; Cressend, Delphine; Perron, Karl; Nkengfack, Augustin Ephrem; Carrupt, Pierre-Alain; Hostettmann, Kurt; Cuendet, Muriel

Global analytical strategy to measure drug-plasma protein interactions: from high-throughput to in-depth analysis

DRUG DISCOVERY TODAY

IF7.5

2013-11-01

PREAI

Vuignier, Karine; Veuthey, Jean-Luc; Carrupt, Pierre-Alain; Schappler, Julie

研究方向