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M

Marcel Ottens

Delft University of Technology

33H指数
290论文数
4.4K被引数
收录论文 104
发表时间
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CFD–DEM characterization of a 250 mL stirred-tank bioreactor for shear-sensitive stem cell microcarrier cultures利用CFD–DEM对适用于剪切敏感干细胞微载体培养的250 mL搅拌罐生物反应器进行表征
errBiochemical Engineering Journal
IF3.8
err2026-08-18
err0
errOAAI
errRamon D. van Valderen; Brenda E. Juarez-Garza; Stijn de Smit; Marcel Ottens; Cees Haringa
err分享
err收藏
Towards Rapid Calibration of Bioprocess Quantification Models Using Single Compound Raman Spectra: A Comparison of Four Approaches利用单组分拉曼光谱快速校准生物过程量化模型：四种方法的比较
errBiotechnology and Bioengineering
IF3.6
err2025-11-01
err0
errOAAI
errMaarten Klaverdijk; Lisa A. Smulders; Marcel Ottens; Marieke E. Klijn
err分享
err收藏
Using generalized quantitative structure–property relationship (QSPR) models to predict host cell protein retention in ion-exchange chromatography使用广义定量构效关系（QSPR）模型预测离子交换色谱中宿主细胞蛋白的保留
errJournal of Chemical Technology & Biotechnology
IF0
err2025-09-07
err0
errOAAI
errTim Neijenhuis; Olivier Le Bussy; Geoffroy Geldhof; Marieke E Klijn; Marcel Ottens
err分享
err收藏
Implicit large eddy simulations for hydrodynamic stress characterization in 125 mL shake flasks for stem cell cultures用于干细胞培养的125 mL摇瓶中水动力应力表征的隐式大涡流模拟
errBIOCHEMICAL ENGINEERING JOURNAL
IF3.8
err2025-07-01
err0
errOAAI
errvan Valderen, Ramon D.; Juarez-Garza, Brenda E.; Klijn, Marieke E.; Ottens, Marcel; Haringa, Cees
err分享
err收藏
Impact of bioreactor process parameters and yeast biomass on Raman spectra生物反应器过程参数和酵母生物量对拉曼光谱的影响
errBiotechnology Progress
IF2.5
err2025-06-16
err0
errOAAI
errMaarten Klaverdijk; Mehrab Nemati; Marcel Ottens; Marieke E. Klijn
err分享
err收藏
Optimization of multi-column chromatography for capture and polishing at high protein load多柱色谱法在高蛋白负载下的捕获与精制优化
errBiotechnology Progress
IF2.5
err2025-06-09
err0
errOAAI
errTiago Castanheira Silva; Madelène Isaksson; Bernt Nilsson; Michel Eppink; Marcel Ottens
err分享
err收藏
Single compound data supplementation to enhance transferability of fermentation specific Raman spectroscopy models
errANALYTICAL AND BIOANALYTICAL CHEMISTRY
IF3.8
err2025-02-06
err0
errOAAI
errKlaverdijk, Maarten; Ottens, Marcel; Klijn, Marieke E.
err分享
err收藏
Experimental characterization and prediction of Escherichia coli host cell proteome retention during preparative chromatography
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2024-09-12
err1
errOAAI
errDisela, Roxana; Neijenhuis, Tim; Le Bussy, Olivier; Geldhof, Geoffroy; Klijn, Marieke; Pabst, Martin; Ottens, Marcel
err分享
err收藏
Continuous downstream processing连续下游加工
errSEPARATION AND PURIFICATION TECHNOLOGY
IF9
err2024-06-01
err10
errOAAI
errJungbauer, Alois; Satzer, Peter; Duerauer, Astrid; Azevedo, Ana; Aires-Barros, Raquel; Nilsson, Bernt; Farid, Suzy; Goldrick, Stephen; Ottens, Marcel; Sponchioni, Mattia; Lahore, Hector Marcelo Fernandez
err分享
err收藏
Predicting protein retention in ion-exchange chromatography using an open source QSPR workflow
errBIOTECHNOLOGY JOURNAL
IF3.1
err2024-03-13
err2
errOAAI
errNeijenhuis, Tim; Le Bussy, Olivier; Geldhof, Geoffroy; Klijn, Marieke E.; Ottens, Marcel
err分享
err收藏
Digital twin in high throughput chromatographic process development for monoclonal antibodies
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2024-02-01
err5
errOAAI
errSilva, Tiago Castanheira; Eppink, Michel; Ottens, Marcel
err分享
err收藏
Hydrodynamics of expanded bed adsorption studied through CFD-DEM
errCHEMICAL ENGINEERING SCIENCE
IF4.3
err2023-10-01
err5
errOAAI
errNijssen, Tim M. J.; Padding, Johan T.; Ottens, Marcel
err分享
err收藏
Model-based optimization of multistage ultrafiltration/diafiltration for recovery of canola protein
errFOOD AND BIOPRODUCTS PROCESSING
IF3.4
err2023-08-01
err5
errOAAI
errRizki, Zulhaj; Ravesloot, Richard; van Beckhoven, Ruud; Ottens, Marcel
err分享
err收藏
Real-time detection of mAb aggregates in an integrated downstream process
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2023-06-13
err7
errOAAI
errSao Pedro, Mariana N.; Isaksson, Madelene; Gomis-Fons, Joaquin; Eppink, Michel H. M.; Nilsson, Bernt; Ottens, Marcel
err分享
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Characterisation of the E. coli HMS174 and BLR host cell proteome to guide purification process development
errBIOTECHNOLOGY JOURNAL
IF3.1
err2023-06-05
err7
errOAAI
errDisela, Roxana; Le Bussy, Olivier; Geldhof, Geoffroy; Pabst, Martin; Ottens, Marcel
err分享
err收藏
Model-based optimization approaches for pressure-driven membrane systems
errSEPARATION AND PURIFICATION TECHNOLOGY
IF9
err2023-06-01
err6
errOAAI
errRizki, Zulhaj; Ottens, Marcel
err分享
err收藏
Using artificial neural networks to accelerate flowsheet optimization for downstream process development使用人工神经网络加速下游工艺开发的流程优化
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2023-05-31
err7
errOAAI
errKeulen, Daphne; van der Hagen, Erik; Geldhof, Geoffroy; Le Bussy, Olivier; Pabst, Martin; Ottens, Marcel
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Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage
errNATURE COMMUNICATIONS
IF15.7
err2023-04-06
err6
errOAAI
errRosado-Ramos, Rita; Pocas, Goncalo M.; Marques, Daniela; Foito, Alexandre; Sevillano, David M.; Lopes-da-Silva, Mafalda; Goncalves, Luis G.; Menezes, Regina; Ottens, Marcel; Stewart, Derek; de Opakua, Alain Ibanez; Zweckstetter, Markus; Seabra, Miguel C.; Mendes, Cesar S.; Outeiro, Tiago Fleming; Domingos, Pedro M.; Santos, Claudia N.
err分享
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Design of a microfluidic mixer channel: First steps into creating a fluorescent dye-based biosensor for mAb aggregate detection
errBIOTECHNOLOGY JOURNAL
IF3.1
err2022-11-11
err4
errOAAI
errPedro, Mariana N. Sao; Santos, Mafalda S.; Eppink, Michel H. M.; Ottens, Marcel
err分享
err收藏
Small, smaller, smallest: Miniaturization of chromatographic process development
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2022-10-01
err11
errOAAI
errSilva, Tiago Castanheira; Eppink, Michel; Ottens, Marcel
err分享
err收藏

研究方向

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合作期刊
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H 指数: 106 · 论文数: 642
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H 指数: 104 · 论文数: 706
李
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H 指数: 99 · 论文数: 1.2K
M
Markus Zweckstetter
H 指数: 90 · 论文数: 430
W
Wim Jiskoot
H 指数: 88 · 论文数: 393
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