K. Maskos - Publications, H-index & Citations

K. Maskos

Planegg-Martinsried

42H指数

175论文数

5.2K被引数

收录论文 31

发表时间

WRN structural flexibility showcased through fragment-based lead discovery of inhibitors WRN结构柔韧性通过基于片段的先导化合物发现抑制剂得到展示

Nature Communications

IF15.7

2026-01-03

OAAI

Rachel L. Palte; Mihir Mandal; Justyna Sikorska; Artjohn B. Villafania; Meredith M. Rickard; Robert J. Bauer; Alexei V. Buevich; Xiaomei Chai; Jiafang He; Zahid Hussain; Markus Koglin; Hannah B. MacDonald; My S. Mansueto; Klaus Maskos; Joey L. Methot; Jaclyn Robustelli; Aileen Soriano; Marcel J. Tauchert; Sriram Tyagarajan; Minjia Zhang; Daniel J. Klein; Jacqueline D. Hicks; David G. McLaren; Sandra B. Gabelli; Daniel F. Wyss

Allosteric targeting of RIPK1: discovery of novel inhibitors via parallel virtual screening and structure-guided optimization 别构靶向RIPK1：通过平行虚拟筛选和结构导向优化发现新型抑制剂

RSC Med. Chem.

IF3.6

2025-09-27

PREAI

R. S. K. Vijayan; Matthew M. Hamilton; Dana E. Pfaffinger; Fernando G. Alvarez; Naphtali J. Reyna; Jennifer P. Bardenhagen; Hannah Shepard; Christian Rodriguez; Sunil Goodwani; Yaima Lightfoot; Klaus Maskos; Sven Johannsson; Georg Kempf; Quanyun Alan Xu; Lars Neumann; Yongying Jiang; Mary Geck Do; Philip Jones; Richard T. Lewis; William J. Ray; Jason B. Cross

High-Throughput Evaluation of Novel WRN Inhibitors 高通量评价新型WRN抑制剂

SLAS Discovery

IF2.7

2025-08-25

OAAI

Haiyan Xu; Rachel L. Palte; Meredith M. Rickard; Soon Woo Kwon; Xiaomei Chai; Jing Yuan; John Bassett; Joseph Moran; Markus Koglin; Isaac Musisi; Minjia Zhang; Klaus Maskos; Marcel J. Tauchert; Yu-Shan Cheng; Zixiong Wang; Yi Yang; Abhisek Banerjee; Joanna L. Chen; Indu Bharathan; Lorena Rico; Kaitlyn Logan; My Sam Mansueto; Stuart Shumway; Joey L. Methot; Robert J. Bauer

Discovery and Preclinical Profile of ALG-097558; a Pan-Coronavirus 3CLpro Inhibitor ALG-097558的发现与临床前研究；一种广谱冠状病毒3CL蛋白酶抑制剂

Journal of Medicinal Chemistry

IF6.8

2025-06-30

PREAI

Dorothée Bardiot; David C. McGowan; Kusum Gupta; Jerome Deval; Sandra Chang; Andreas Jekle; Cheng Liu; Sarah Stevens; Vladimir Serebryany; Marcel J. Tauchert; Klaus Maskos; Antitsa D. Stoycheva; Suping Ren; Ruchika Jaisinghani; Marine O. Faucher; Tse-I Lin; Sandro Boland; Patrick Chaltin; Arnaud Marchand; Jurgen Wuyts; Steven De Jonghe; Dirk Jochmans; Sreenivasa Anugu; Vamshi Baloju; Kiran Deta; Michael Welch; Pieter Leyssen; Johan Neyts; Manon Laporte; Rana Abdelnabi; Haiyang Hu; Peng Zhang; Kha Le; Sushmita Chanda; David B. Smith; Pierre Raboisson; Leonid Beigelman; Julian A. Symons; Lawrence Blatt; Koen Vandyck

The Discovery of Bridged Benzoazepine Amides as Selective Allosteric Modulators of RIPK1

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2025-04-01

PREAI

Chen, Joanna L.; Methot, Joey L.; Mitcheltree, Matthew J.; Musacchio, Andrew; Corcoran, Emily B.; Feng, Guo; Lammens, Alfred; Maskos, Klaus; Palte, Rachel L.; Rickard, Meredith M.; Otte, Karin M.; Mansueto, My S.; Venkat, Sriraman; Sondey, Christopher; Thomsen, Maren; Lesburg, Charles A.; Fradera, Xavier; Fell, Matthew J.; DiMauro, Erin F.; Siliphaivanh, Phieng

Discovery and Preclinical Profile of ALG-055009, a Potent and Selective Thyroid Hormone Receptor Beta (THR-β) Agonist for the Treatment of MASH

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-09-02

PREAI

Vandyck, Koen; Mcgowan, David C.; Luong, Xuan G.; Stevens, Sarah K.; Jekle, Andreas; Gupta, Kusum; Misner, Dinah L.; Chanda, Sushmita; Serebryany, Vladimir; Welch, Michael; Hu, Haiyang; Lv, Zhidan; Williams, Caroline; Maskos, Klaus; Lammens, Alfred; Stoycheva, Antitsa D.; Lin, Tse-, I; Blatt, Lawrence M.; Beigelman, Leonid N.; Symons, Julian A.; Raboisson, Pierre; Deval, Jerome

A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors

NATURE COMMUNICATIONS

IF15.7

2018-03-23

OAAI

Vigolo, Michele; Chambers, Melissa G.; Willen, Laure; Chevalley, Dehlia; Maskos, Klaus; Lammens, Alfred; Tardivel, Aubry; Das, Dolon; Kowalczyk-Quintas, Christine; Schuepbach-Mallepell, Sonia; Smulski, Cristian R.; Eslami, Mahya; Rolink, Antonius; Hummler, Edith; Samy, Eileen; Nanfack, Yves Fomekong; Mackay, Fabienne; Liao, Maofu; Hess, Henry; Jiang, Xuliang; Schneider, Pascal

Molecular Insights into Function and Competitive Inhibition of Pseudomonas aeruginosa Multiple Virulence Factor Regulator

MBIO

IF4.7

2018-03-07

OAAI

Kitao, Tomoe; Lepine, Francois; Babloudi, Seda; Walte, Frederick; Steinbacher, Stefan; Maskos, Klaus; Blaesse, Michael; Negri, Michele; Pucci, Michael; Zahler, Bob; Felici, Antonio; Rahme, Laurence G.

Buffer and additive thermofluor screening of wild type human interferon gamma and mutant proteins

THERMOCHIMICA ACTA

IF3.5

2017-08-01

PREAI

Tileva, M.; Krachmarova, E.; Taneva, S. G.; Todinova, S.; Maskos, K.; Ivanov, I.; Nacheva, G.

Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2016-04-06

OAAI

Bergeron, Philippe; Koehler, Michael F. T.; Blackwood, Elizabeth M.; Bowman, Krista; Clark, Kevin; Firestein, Ron; Kiefer, James R.; Maskos, Klaus; McCleland, Mark L.; Orren, Linda; Ramaswamy, Sreemathy; Salphati, Laurent; Schmidt, Steve; Schneider, Elisabeth V.; Wu, Jiansheng; Beresini, Maureen

Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2016-01-20

OAAI

Koehler, Michael F. T.; Bergeron, Philippe; Blackwood, Elizabeth M.; Bowman, Krista; Clark, Kevin R.; Firestein, Ron; Kiefer, James R.; Maskos, Klaus; McCleland, Mark L.; Orren, Linda; Salphati, Laurent; Schmidt, Steve; Schneider, Elisabeth V.; Wu, Jiansheng; Beresini, Maureen H.

Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties 异聚BAFF和APRIL细胞因子的化学计量决定了它们的受体结合和信号传导特性

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-06-01

OAAI

Schuepbach-Mallepell, Sonia; Das, Dolon; Willen, Laure; Vigolo, Michele; Tardivel, Aubry; Lebon, Luc; Kowalczyk-Quintas, Christine; Nys, Josquin; Smulski, Cristian; Zheng, Timothy S.; Maskos, Klaus; Lammens, Alfred; Jiang, Xuliang; Hess, Henry; Tan, Seng-Lai; Schneider, Pascal

Structure-kinetic relationship study of CDK8/CycC specific compounds

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-04-29

116

OAAI

Schneider, Elisabeth V.; Boettcher, Jark; Huber, Robert; Maskos, Klaus; Neumann, Lars

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-09-01

132

OAAI

Gerritz, Samuel W.; Cianci, Christopher; Kim, Sean; Pearce, Bradley C.; Deminie, Carol; Discotto, Linda; McAuliffe, Brian; Minassian, Beatrice F.; Shi, Shuhao; Zhu, Shirong; Zhai, Weixu; Pendri, Annapurna; Li, Guo; Poss, Michael A.; Edavettal, Suzanne; McDonnell, Patricia A.; Lewis, Hal A.; Maskos, Klaus; Moertl, Mario; Kiefersauer, Reiner; Steinbacher, Stefan; Baldwin, Eric T.; Metzler, William; Bryson, James; Healy, Matthew D.; Philip, Thomas; Zoeckler, Mary; Schartman, Richard; Sinz, Michael; Leyva-Grado, Victor H.; Hoffmann, Hans-Heinrich; Langley, David R.; Meanwell, Nicholas A.; Krystal, Mark

The Dimer Interface of the Membrane Type 1 Matrix Metalloproteinase Hemopexin Domain CRYSTAL STRUCTURE AND BIOLOGICAL FUNCTIONS

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-03-01

OAAI

Tochowicz, Anna; Goettig, Peter; Evans, Richard; Visse, Robert; Shitomi, Yasuyuki; Palmisano, Ralf; Ito, Noriko; Richter, Klaus; Maskos, Klaus; Franke, Daniel; Svergun, Dmitri; Nagase, Hideaki; Bode, Wolfram; Itoh, Yoshifumi

A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2010-11-01

PREAI

Buttar, David; Colclough, Nicola; Gerhardt, Stefan; MacFaul, Philip A.; Phillips, Scott D.; Plowright, Alleyn; Whittamore, Paul; Tam, Kin; Maskos, Klaus; Steinbacher, Stefan; Steuber, Holger

Phosphorylation of the human full-length protein kinase Cι

JOURNAL OF PROTEOME RESEARCH

IF3.6

2008-05-20

PREAI

Macek, Boris; Benda, Christian; Jestel, Anja; Maskos, Klaus; Mann, Matthias; Messerschmidt, Albrecht

X-ray structures of Sap 1 and Sap5:: Structural comparison of the secreted aspartic proteinases from Candida albicans

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2008-04-02

PREAI

Borelli, Claudia; Ruge, Elisabeth; Lee, Jung Hoon; Schaller, Martin; Vogelsang, Alexandra; Monod, Michel; Korting, Hans Christian; Huber, Robert; Maskos, Klaus

The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2007-05-17

PREAI

Borelli, Claudia; Ruge, Elisabeth; Schaller, Martin; Monod, Michel; Korting, Hans Christian; Huber, Robert; Maskos, Klaus

Matrix metalloproteinases, tissue inhibitors of MMPs and TACE in experimental cerebral malaria

LABORATORY INVESTIGATION

IF4.2

2006-09-01

OAAI

Van den Steen, Philippe E.; Van Aelst, Ilse; Starckx, Sofie; Maskos, Klaus; Opdenakker, Ghislain; Pagenstecher, Axel

研究方向