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Sharadha Subramanian

Novartis
H指数:13
被引数:562

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Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis
2020-02-1731
PREAI
Design and Discovery of N-(3-(2-(2-Hydroxyethoxy)-6morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the Clinic
2019-05-0632
OAAI
Pharmacological profile and anti-tumor properties of LXH254, a highly selective RAF kinase inhibitor
2018-07-014
PRE
Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-lmidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3
2017-10-1034
PREAI
Design and Discovery of N-(2-Methyl-5′-morpholino-6′-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers
2017-06-0846
PREAI
Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the Treatment of Metastatic Melanoma
2015-08-0348
OA
Inhibiting mutated KRAS, a broken switch of effector pathways
2015-02-050
PRE