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J

Johanna M. Jansen

Novartis
H指数:24
被引数:2,487

个人简介

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教育背景

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工作经历

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荣誉奖项

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CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

CACHE (计算命中发现实验的关键评估): 一项公私合作伙伴关系基准计划，旨在开发命中发现的计算方法

NATURE REVIEWS CHEMISTRY
IF51.7
2022-02-1538
OA
Ackloo, Suzanne; Al-awar, Rima; Amaro, Rommie E.; Arrowsmith, Cheryl H.; Azevedo, Hatylas; Batey, Robert A.; Bengio, Yoshua; Betz, Ulrich A. K.; Bologa, Cristian G.; Chodera, John D.; Cornell, Wendy D.; Dunham, Ian; Ecker, Gerhard F.; Edfeldt, Kristina; Edwards, Aled M.; Gilson, Michael K.; Gordijo, Claudia R.; Hessler, Gerhard; Hillisch, Alexander; Hogner, Anders; Irwin, John J.; Jansen, Johanna M.; Kuhn, Daniel; Leach, Andrew R.; Lee, Alpha A.; Lessel, Uta; Morgan, Maxwell R.; Moult, John; Muegge, Ingo; Oprea, Tudor, I; Perry, Benjamin G.; Riley, Patrick; Rousseaux, Sophie A. L.; Saikatendu, Kumar Singh; Santhakumar, Vijayaratnam; Schapira, Matthieu; Scholten, Cora; Todd, Matthew H.; Vedadi, Masoud; Volkamer, Andrea; Willson, Timothy M.
Evolution of Novartis' Small Molecule Screening Deck Design

诺华小分子筛板设计的演变

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-11-0336
PREAI
Schuffenhauer, Ansgar; Schneider, Nadine; Hintermann, Samuel; Auld, Douglas; Blank, Jutta; Cotesta, Simona; Engeloch, Caroline; Fechner, Nikolas; Gaul, Christoph; Giovannoni, Jerome; Jansen, Johanna; Joslin, John; Krastel, Philipp; Lounkine, Eugen; Manchester, John; Monovich, Lauren G.; Pelliccioli, Anna Paola; Schwarze, Manuel; Shultz, Michael D.; Stiefl, Nikolaus; Baeschlin, Daniel K.
Rethinking drug design in the artificial intelligence era

人工智能时代的药物设计再思考

NATURE REVIEWS DRUG DISCOVERY
IF101.8
2019-12-04405
OAAI
Schneider, Petra; Walters, W. Patrick; Plowright, Alleyn T.; Sieroka, Norman; Listgarten, Jennifer; Goodnow, Robert A., Jr.; Fisher, Jasmin; Jansen, Johanna M.; Duca, Jose S.; Rush, Thomas S.; Zentgraf, Matthias; Hill, John Edward; Krutoholow, Elizabeth; Kohler, Matthias; Blaney, Jeff; Funatsu, Kimito; Luebkemann, Chris; Schneider, Gisbert
Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-lmidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2017-10-1034
PREAI
Wagman, Allan S.; Boyce, Rustum S.; Brown, Sean P.; Fang, Eric; Goff, Dane; Jansen, Johanna M.; Le, Vincent P.; Levine, Barry H.; Ng, Simon C.; Ni, Zhi-Jie; Nuss, John M.; Pfister, Keith B.; Ramurthy, Savithri; Renhowe, Paul A.; Ring, David B.; Shu, Wei; Subramanian, Sharadha; Zhou, Xiaohui A.; Shafer, Cynthia M.; Harrison, Stephen D.; Johnson, Kirk W.; Bussiere, Dirksen E.
Design and Discovery of N-(2-Methyl-5′-morpholino-6′-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2017-06-0846
PREAI
Nishiguchi, Gisele A.; Rico, Alice; Tanner, Huw; Aversa, Robert J.; Taft, Benjamin R.; Subramanian, Sharadha; Setti, Lina; Burger, Matthew T.; Wan, Lifeng; Tamez, Victoriano; Smith, Aaron; Lou, Yan; Barsanti, Paul A.; Appleton, Brent A.; Mamo, Mulugeta; Tandeske, Laura; Dix, Ina; Tellew, John E.; Huang, Shenlin; Griner, Lesley A. Mathews; Cooke, Vesselina G.; Van Abbema, Anne; Merritt, Hanne; Ma, Sylvia; Gampa, Kalyani; Feng, Fei; Yuan, Jing; Wang, Yingyun; Haling, Jacob R.; Vaziri, Sepideh; Hekmat-Nejad, Mohammad; Jansen, Johanna M.; Polyakov, Valery; Zang, Richard; Sethuraman, Vijay; Amiri, Payman; Singh, Mallika; Lees, Emma; Shao, Wenlin; Stuart, Darrin D.; Dillon, Michael P.; Ramurthy, Savithri
Inhibiting mutated KRAS, a broken switch of effector pathways
MOLECULAR CANCER RESEARCH
IF4.7
2015-02-050
PRE
Jansen, Johanna; Jahnke, Wolfgang; Fong, Susan; Tandeske, Laura; Wartchow, Charles; Pfister, Keith; Zavorotinskaya, Tatiana; Blechschmidt, Anke; Bussiere, Dirksen; Dai, Yumin; Dove, Jeff; Fang, Eric; Farley, David; Florent, Jean-Michel; Fuller, John; Gokhin, Simona; Gossert, Alvar; Hekmat-Nejad, Mohammad; Henry, Chrystele; Klopp, Julia; Lenahan, Bill; Lingel, Andreas; Meyer, Arndt; Narberes, Jamie; Pardee, Gwynn; Paris, C. Gregory; Ramurthy, Savithri; Renhowe, Paul; Rieffel, Sebastien; Shoemaker, Kevin; Subramanian, Sharadha; Tsang, Tiffany; Widger, Stephania; Widmer, Armin; Zaror, Isabel; Hardy, Stephen
Design, Structure-Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2008-12-29164
PREAI
Renhowe, Paul A.; Pecchi, Sabina; Shafer, Cynthia M.; Machajewski, Timothy D.; Jazan, Elisa M.; Taylor, Clarke; Antonios-McCrea, William; McBride, Christopher M.; Frazier, Kelly; Wiesmann, Marion; Lapointe, Gena R.; Feucht, Paul H.; Warne, Robert L.; Heise, Carla C.; Menezes, Daniel; Aardalen, Kimberly; Ye, Helen; He, Molly; Le, Vincent; Vora, Jayesh; Jansen, Johanna M.; Wernette-Hammond, Mary Ellen; Harris, Alex L.

研究方向

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É
Éric Martin
H 指数:26论文数:205被引数:2,851
S
Savithri Ramurthy
H 指数:17论文数:52被引数:1,897
S
Sharadha Subramanian
H 指数:13论文数:35被引数:563
P
Paul A. Renhowe
H 指数:19论文数:61被引数:1,300
W
W. Patrick Walters
H 指数:34论文数:144被引数:8,653
M
Mika Lindvall
H 指数:24论文数:62被引数:4,215
E
Eric Fang
H 指数:35论文数:77被引数:6,357
K
Keith Pfister
H 指数:10论文数:25被引数:574
S
Susan Fong
H 指数:17论文数:42被引数:1,513
C
Cynthia M. Shafer
H 指数:19论文数:85被引数:1,418