Tommy Liljefors - Publications, H-index & Citations

Tommy Liljefors

University of Copenhagen

43H指数

289论文数

6.6K被引数

收录论文 52

发表时间

Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABAA receptors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2011-01-01

PREAI

Nilsson, Jakob; Gidlof, Ritha; Nielsen, Elsebet Ostergaard; Liljefors, Tommy; Nielsen, Mogens; Sterner, Olov

Rational Design of α-Conotoxin Analogues Targeting α7 Nicotinic Acetylcholine Receptors IMPROVED ANTAGONISTIC ACTIVITY BY INCORPORATION OF PROLINE DERIVATIVES

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2009-04-01

OAAI

Armishaw, Christopher; Jensen, Anders A.; Balle, Thomas; Clark, Richard J.; Harpsoe, Kasper; Skonberg, Christian; Liljefors, Tommy; Stromgaard, Kristian

Complementary Three-Dimensional Quantitative Structure-Activity Relationship Modeling of Binding Affinity and Functional Potency: A Study on α4β2 Nicotinic Ligands

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-03-20

PREAI

Tosco, Paolo; Ahring, Philip K.; Dyhring, Tino; Peters, Dan; Harpsoe, Kasper; Liljefors, Tommy; Balle, Thomas

SHOP: Receptor-Based Scaffold HOPping by GRID-Based Similarity Searches

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2009-03-05

PREAI

Bergmann, Rikke; Liljefors, Tommy; Sorensen, Morten D.; Zamora, Ismael

Novel Acetylcholine and Carbamoylcholine Analogues: Development of a Functionally Selective α4β2 Nicotinic Acetylcholine Receptor Agonist

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-11-07

PREAI

Hansen, Camilla P.; Jensen, Anders A.; Christensen, Jeppe K.; Balle, Thomas; Lijefors, Tommy; Frolund, Bente

Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABAA receptors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2008-07-01

PREAI

Lager, Erik; Nilsson, Jakob; Nielsen, Elsebet Ostergaard; Nielsen, Mogens; Liljefors, Tommy; Sterner, Olov

Structures of the ligand-binding core of iG1uR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-02-13

PREAI

Beich-Frandsen, Mads; Pickering, Darryl S.; Mirza, Osman; Johansen, Tommy N.; Greenwood, Jeremy; Vestergaard, Bente; Schousboe, Arne; Gajhede, Michael; Liljefors, Tommy; Kastrup, Jette S.

Pharmacological characteristics and binding modes of caracurine V analogues and related compounds at the neuronal α7 nicotinic acetylcholine receptor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2007-08-28

PREAI

Jensen, Anders A.; Zlotos, Darius P.; Liljefors, Tommy

Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5 - Structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2007-08-01

OAAI

Hald, Helle; Naur, Peter; Pickering, Darryl S.; Sprogoe, Desiree; Madsen, Ulf; Timmermann, Daniel B.; Ahring, Philip K.; Liljefors, Tommy; Schousboe, Arne; Egebjerg, Jan; Gajhede, Michael; Kastrup, Jette Sandholm

5-substituted imidazole-4-acetic acid analogues:: Synthesis, modeling, and pharmacological characterization of a series of novel γ-aminobutyric AcidC receptor agonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2007-07-26

PREAI

Madsen, Christian; Jensen, Anders A.; Liljefors, Tommy; Kristiansen, Uffe; Nielsen, Birgitte; Hansen, Camilla P.; Larsen, Mogens; Ebert, Bjarke; Bang-Andersen, Benny; Krogsgaard-Larsen, Povl; Frolund, Bente

4-aryl-5-(4-piperidyl)-3-isoxazolol GABAA antagonists:: Synthesis, pharmacology, and structure-activity relationships

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2007-03-22

PREAI

Frolund, Bente; Jensen, Lars S.; Storustovu, Signe I.; Stensbol, Tine B.; Ebert, Bjarke; Kehler, Jan; Krogsgaard-Larsen, Povl; Liljefors, Tommy

New Ligands with affinity for the α4β2 subtype of nicotinic acetylcholine receptors.: Synthesis, receptor binding, and 3D-QSAR modeling

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-05-05

PREAI

Audouze, Karine; Ostergaard Nielsen, Elsebet; Olsen, Gunnar M.; Ahring, Philip; Jorgensen, Tino Dyhring; Peters, Dan; Liljefors, Tommy; Balle, Thomas

4-quinolone derivatives:: High-affinity ligands at the benzodiazepine site of brain GABAA receptors. synthesis, pharmacology, and pharmacophore modeling

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-03-14

PREAI

Lager, E; Andersson, P; Nilsson, J; Pettersson, I; Nielsen, EO; Nielsen, M; Sterner, O; Liljefors, T

Assessment of the combined approach of N-alkylation and salt formation to enhance aqueous solubility of tertiary amines using bupivacaine as a model drug

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2005-01-01

PREAI

Nielsen, AB; Frydenvang, K; Liljefors, T; Buur, A; Larsen, C

Potent 4-aryl- or 4-arylalkyl-substituted 3-isoxazolol GABAA antagonists:: Synthesis, pharmacology, and molecular modeling

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2004-12-22

PREAI

Frolund, B; Jensen, LS; Guandalini, L; Canillo, C; Vestergaard, HT; Kristiansen, U; Nielsen, B; Stensbol, TB; Madsen, C; Krogsgaard-Larszen, P; Liljefors, T

GABAA agonists and partial agonists:: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic

BIOCHEMICAL PHARMACOLOGY

IF5.6

2004-10-01

117

PREAI

Krogsgaard-Larsen, P; Frolund, B; Liljefors, T; Ebert, B

Aqueous solubility study of salts of benzylamine derivatives and p-substituted benzoic acid derivatives using X-ray crystallographic analysis

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2004-01-01

PREAI