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收藏Synthesis of a Long Acting HIV Protease Inhibitor via Metal or Enzymatic Reduction of the Appropriate Chloro Ketone and Selective Zinc Enolate Condensation with an Amino Epoxide
Houpis, Ioannis N.; Liu, Renmao; Liu, Lin; Wang, Yanfei; Dong, Nengfa; Zhao, Xiangan; Zhang, Yan; Xiao, Tingting; Wang, Youchu; Depre, Dominique; Nettekoven, Ulrike; Vogel, Michael; Wilson, Rob; Collier, Steve
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收藏Stereoselective C-Glycosylation Reactions with Arylzinc Reagents
Lemaire, Sebastien; Houpis, Ioannis N.; Xiao, Tingting; Li, Juanjuan; Digard, Eric; Gozlan, Charlotte; Liu, Renmao; Gavryushin, Andrey; Diene, Coura; Wang, Youchu; Farina, Vittorio; Knochel, Paul
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收藏Practical Synthesis of (2′R)-2′-Deoxy-2′-C-methyluridine by Highly Diastereoselective Homogeneous Hydrogenation
Lemaire, Sebastien; Houpis, Ioannis; Wechselberger, Rainer; Langens, Jaak; Vermeulen, Wim A. A.; Smets, Nico; Nettekoven, Ulrike; Wang, Youchu; Xiao, Tingting; Qu, Haisheng; Liu, Renmao; Jonckers, Tim H. M.; Raboisson, Pierre; Vandyck, Koen; Nilsson, Karl M.; Farina, Vittorio
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收藏Efficient large-scale synthesis of BILN 2061, a potent HCV protease inhibitor, by a convergent approach based on ring-closing metathesis
Yee, Nathan K.; Farina, Vittorio; Houpis, Ioannis N.; Haddad, Nizar; Frutos, Rogelio P.; Gallou, Fabrice; Wang, Xiao-Jun; Wei, Xudong; Simpson, Robert D.; Feng, Xuwu; Fuchs, Victor; Xu, Yibo; Tan, Jonathan; Zhang, Li; Xu, Jinghua; Smith-Keenan, Lana L.; Vitous, Jana; Ridges, Michael D.; Spinelli, Earl M.; Johnson, Michael; Donsbach, Kai; Nicola, Thomas; Brenner, Michael; Winter, Eric; Kreye, Paul; Samstag, Wendelin
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收藏Synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid (vinyl-ACCA) derivatives:: Key intermediates for the preparation of inhibitors of the hepatitis C virus NS3 protease
Beaulieu, PL; Gillard, J; Bailey, MD; Boucher, C; Duceppe, JS; Simoneau, B; Wang, XJ; Zhang, L; Grozinger, K; Houpis, I; Farina, V; Heimroth, H; Krueger, T; Schnaubelt, J
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收藏Synthesis of a peroxime proliferator activated receptor (PPAR) α/γ agonist via stereocontrolled Williamson ether synthesis and stereospecific SN2 reaction of S-2-chloro propionic acid with phenoxides
Aikins, JA; Haurez, M; Rizzo, JR; Van Hoeck, JP; Brione, W; Kestemont, JP; Stevens, C; Lemair, X; Stephenson, GA; Marlot, E; Forst, M; Houpis, IN
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收藏Synthesis of a muscarinic receptor antagonist via a diastereoselective Michael reaction, selective deoxyfluorination and aromatic metal-halogen exchange reaction (vol 66, pg 6785, 2001)
Mase, T; Houpis, IN; Akao, A; Dorziotis, I; Emerson, K; Hoang, T; Iida, T; Itoh, T; Kamei, K; Kato, S; Kawasaki, M; Lang, FR; Lee, J; Lynch, J; Maligres, P; Molina, A; Nemoto, T; Okada, S; Reamer, R; Song, ZGJ; Tschaen, D; Wada, T; Zewge, D; Volante, RP; Reider, PJ; Tomimoto, K
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收藏Synthesis of a muscarinic receptor antagonist via a diastereoselective Michael reaction, selective deoxyfluorination and aromatic metal-halogen exchange reaction
Mase, T; Houpis, IN; Akao, A; Dorziotis, I; Emerson, K; Hoang, T; Iida, T; Itoh, T; Kamei, K; Kato, S; Kato, Y; Kawasaki, M; Lang, FR; Lee, JM; Lynch, J; Maligres, P; Molina, A; Nemoto, T; Okada, S; Reamer, R; Song, JZ; Tschaen, D; Wada, T; Zewge, D; Volante, RP; Reider, PJ; Tomimoto, K
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