Uli Hacksell - Publications, H-index & Citations

Uli Hacksell

universidade de sao paulo

41H指数

310论文数

7.3K被引数

收录论文 41

发表时间

On the Discovery and Development of Pimavanserin: A Novel Drug Candidate for Parkinson's Psychosis

NEUROCHEMICAL RESEARCH

IF3.8

2014-03-30

126

OAAI

Hacksell, Uli; Burstein, Ethan S.; McFarland, Krista; Mills, Roger G.; Williams, Hilde

Pimavanserin, a selective serotonin (5-HT)2A-inverse agonist, enhances the efficacy and safety of risperidone, 2 mg/day, but does not enhance efficacy of haloperidol, 2 mg/day: Comparison with reference dose risperidone, 6 mg/day

SCHIZOPHRENIA RESEARCH

IF3.5

2012-11-01

OAAI

Meltzer, Herbert Y.; Elkis, Helio; Vanover, Kimberly; Weiner, David M.; van Kammen, Daniel P.; Peters, Perry; Hacksell, Uli

II. In vitro evidence that (-)-OSU6162 and (+)-OSU6162 produce their behavioral effects through 5-HT2A serotonin and D2 dopamine receptors

JOURNAL OF NEURAL TRANSMISSION

IF4

2011-08-25

PREAI

Burstein, Ethan S.; Carlsson, Maria L.; Owens, Michelle; Ma, Jian-Nong; Schiffer, Hans H.; Carlsson, Arvid; Hacksell, Uli

Optimization of isochromanone based urotensin II receptor agonists

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2010-07-01

PREAI

Lehmann, Fredrik; Currier, Erika A.; Olsson, Roger; Ma, Jian-Nong; Burstein, Ethan S.; Hacksell, Uli; Luthman, Kristina

Novel and potent small-molecule urotensin II receptor agonists

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2009-07-01

PREAI

Lehmann, Fredrik; Currier, Erika A.; Clemons, Bryan; Hansen, Lars K.; Olsson, Roger; Hacksell, Uli; Luthman, Kristina

Design, Synthesis, and Structure-Activity Analysis of Isoform-Selective Retinoic Acid Receptor β Ligands

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-02-24

PREAI

Lund, Birgitte W.; Knapp, Anne Eeg; Piu, Fabrice; Gauthier, Natalie K.; Begtrup, Mikael; Hacksell, Uli; Olsson, Roger

Analysis of molecular determinants of affinity and relative efficacy of a series of R- and S-2-(dipropylamino)tetralins at the 5-HT1A serotonin receptor

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2009-01-30

OAAI

Alder, JT; Hacksell, U; Strange, PG

Constitutively active mutants of the histamine H1 receptor suggest a conserved hydrophobic asparagine-cage that constrains the activation of class a g protein-coupled receptors

MOLECULAR PHARMACOLOGY

IF3

2008-01-01

PREAI

Bakker, Remko A.; Jongejan, Aldo; Sansuk, Kamonchanok; Hacksell, Uli; Timmerman, Henk; Brann, Mark R.; Weiner, Dave M.; Pardo, Leonardo; Leurs, Rob

ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2007-08-01

PREAI

Gardell, Luis R.; Vanover, Kimberly E.; Pounds, Linda; Johnson, Robert W.; Barido, Richard; Anderson, Gary T.; Veinbergs, Isaac; Dyssegaard, Agnete; Brunmark, Per; Tabatabaei, Ali; Davis, Robert E.; Brann, Mark R.; Hacksell, Uli; Bonhaus, Douglas W.

In vitro pharmacology of clinically used central nervous system-active drugs as inverse H1 receptor agonists

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2007-07-01

PREAI

Bakker, R. A.; Nicholas, M. W.; Smith, T. T.; Burstein, E. S.; Hacksell, U.; Timmerman, H.; Leurs, R.; Brann, M. R.; Weiner, D. M.

Novel potent and efficacious nonpeptidic urotensin II receptor agonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-03-10

PREAI

Lehmann, F; Pettersen, A; Currier, EA; Sherbukhin, V; Olsson, R; Hacksell, U; Luthman, K

Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors:: Identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2005-12-01

168

PREAI

Burstein, ES; Ma, J; Wong, S; Gao, Y; Pham, E; Knapp, AE; Nash, NR; Olsson, R; Davis, RE; Hacksell, U; Weiner, DM; Brann, MR

Identification of novel subtype selective RAR agonists

BIOCHEMICAL PHARMACOLOGY

IF5.6

2005-12-01

PREAI

Piu, F; Gauthier, NK; Olsson, R; Currier, EA; Lund, BW; Croston, GE; Hacksell, U; Brann, MR

Isochromanone-based urotensin-II receptor agonists

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2005-04-01

PREAI

Lehmann, F; Currier, EA; Olsson, R; Hacksell, U; Luthman, K

Reduction of haloperidol-induced side effects by ACP-103 in healthy volunteers.

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2005-02-01

PREAI

Grahnen, AE; Vanover, KE; Weiner, DM; Nilsson, L; Tolf, B; Hacksell, U; Davis, MR

Pharmacological characterization of AC-90179[2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)acetamide hydrochloride]:: A selective serotonin 2A receptor inverse agonist

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2004-09-01

PREAI

Vanover, KE; Harvey, SC; Son, T; Bradley, SR; Kold, H; Makhay, M; Veinbergs, I; Spalding, TA; Weiner, DM; Andersson, CM; Tolf, BR; Brann, MR; Hacksell, U; Davis, RE

The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine

PSYCHOPHARMACOLOGY

IF3.3

2004-07-16

219

PREAI

Weiner, DM; Meltzer, HY; Veinbergs, I; Donohue, EM; Spalding, TA; Smith, TT; Mohell, N; Harvey, SC; Lameh, J; Nash, N; Vanover, KE; Olsson, R; Jayathilake, K; Lee, M; Levey, AI; Hacksell, U; Burstein, ES; Davis, RE; Brann, M

8R-lisuride is a potent stereospecific histamine H1-receptor partial agonist

MOLECULAR PHARMACOLOGY

IF3

2004-03-01

PREAI

Bakker, RA; Weiner, DM; ter Laak, T; Beuming, T; Zuiderveld, OP; Edelbroek, M; Hacksell, U; Timmerman, H; Brann, MR; Leurs, R

Pharmacology of polymorphic variants of the human 5-HT1A receptor

BIOCHEMICAL PHARMACOLOGY

IF5.6

2004-02-01

PREAI

Del Tredici, AL; Schiffer, HH; Burstein, ES; Lameh, J; Mohell, N; Hacksell, U; Brann, MR; Weiner, DM