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D

David O. Toft

mayo clinic

67H指数
187论文数
1.7W被引数
收录论文 36
发表时间
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GCUNC-45 is a novel regulator for the progesterone receptor/hsp90 chaperoning pathway
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err73
errOAAI
errChadli, A; Graham, JD; Abel, MG; Jackson, TA; Gordon, DF; Wood, WM; Felts, SJ; Horwitz, KB; Toft, D
err分享
err收藏
FKBP51 Promotes Assembly of the Hsp90 Chaperone Complex and Regulates Androgen Receptor Signaling in Prostate Cancer Cells
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err156
errOAAI
errNi, Li; Yang, Chun-Song; Gioeli, Daniel; Frierson, Henry; Toft, David O.; Paschal, Bryce M.
err分享
err收藏
Phase I study of tanespimycin in combination with bortezomib in patients with advanced solid malignancies晚期实体恶性肿瘤患者tanespimycin联合硼替佐米的I期研究
errINVESTIGATIONAL NEW DRUGS
IF2.7
err2013-10-01
err14
errOAAI
errSchenk, Erin; Hendrickson, Andrea E. Wahner; Northfelt, Donald; Toft, David O.; Ames, Matthew M.; Menefee, Michael; Satele, Daniel; Qin, Rui; Erlichman, Charles
err分享
err收藏
Characterization of plant p23-like proteins for their co-chaperone activities植物p23-like蛋白共伴侣活性的表征
errCELL STRESS & CHAPERONES
IF3.2
err2010-09-01
err24
errOAAI
errZhang, Zhongming; Sullivan, William; Felts, Sara J.; Prasad, Bishun D.; Toft, David O.; Krishna, Priti
err分享
err收藏
Phase I study of 17-allylamino-17 demethoxygeldanamycin, gemcitabine and/or cisplatin in patients with refractory solid tumors
errINVESTIGATIONAL NEW DRUGS
IF2.7
err2010-01-15
err36
errOAAI
errHubbard, Joleen; Erlichman, Charles; Toft, David O.; Qin, Rui; Stensgard, Bridget A.; Felten, Sara; Ten Eyck, Cynthia; Batzel, Gretchen; Ivy, S. Percy; Haluska, Paul
err分享
err收藏
P-glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response
errCANCER RESEARCH
IF16.6
err2008-09-14
err76
errOAAI
errMcCollum, Andrea K.; TenEyck, Cynthia J.; Stensgard, Bridget; Morlan, Bruce W.; Ballman, Karla V.; Jenkins, Robert B.; Toft, David O.; Erlichman, Charles
err分享
err收藏
GCUNC45 is the first Hsp90 co-chaperone to show α/β isoform specificity
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2008-04-01
err45
errOAAI
errChadli, Ahmed; Felts, Sara J.; Toft, David O.
err分享
err收藏
Functioning of the Hsp90 machine in chaperoning checkpoint kinase 1 (Chk1) and the progesterone receptor (PR)
errCELL STRESS & CHAPERONES
IF3.2
err2007-01-01
err30
errOAAI
errFelts, Sara J.; Karnitz, Larry M.; Toft, David O.
err分享
err收藏
An acetylation site in the middle domain of Hsp90 regulates chaperone function
errMOLECULAR CELL
IF16.6
err2007-01-01
err414
errOAAI
errScroggins, Bradley T.; Robzyk, Kenneth; Wang, Dongxia; Marcu, Monica G.; Tsutsumi, Shinji; Beebe, Kristin; Cotter, Robert J.; Felts, Sara; Toft, David; Karnitz, Larry; Rosen, Neal; Neckers, Len
err分享
err收藏
Up-regulation of heat shock protein 27 induces resistance to 17-allylamino-demethoxygeldanamycin through a glutathione-mediated mechanism
errCANCER RESEARCH
IF16.6
err2006-11-15
err156
errOAAI
errMcCollum, Andrea K.; TenEyck, Cynthia J.; Sauer, Brian M.; Toft, David O.; Erlichman, Charles
err分享
err收藏
A phase I trial of twice-weekly 17-allylamino-demethoxy-geldanamycin in patients with advanced cancer
errCLINICAL CANCER RESEARCH
IF10.2
err2006-10-24
err116
errOAAI
errNowakowski, Grzegorz S.; McCollum, Andrea K.; Ames, Matthew M.; Mandrekar, Sumithra J.; Reid, Joel M.; Adjei, Alex A.; Toft, David O.; Safgren, Stephanie L.; Erlichman, Charles
err分享
err收藏
Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2006-02-01
err88
errOAAI
errArlander, SJH; Felts, SJ; Wagner, JM; Stensgard, B; Toft, DO; Karnitz, LM
err分享
err收藏
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptorHDAC6调节糖皮质激素受体的Hsp90乙酰化和伴侣依赖性激活
errMOLECULAR CELL
IF16.6
err2005-05-01
err1.1K
errOAAI
errKovacs, JJ; Murphy, PJM; Gaillard, S; Zhao, XA; Wu, JT; Nicchitta, CV; Yoshida, M; Toft, DO; Pratt, WB; Yao, TP
err分享
err收藏
Hsp90: from structure to phenotype
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2004-12-01
err68
PREAI
errJackson, SE; Queitsch, C; Toft, D
err分享
err收藏
Requirement of heat shock protein 90 for human hepatitis B virus reverse transcriptase function
errJOURNAL OF VIROLOGY
IF3.8
err2004-12-01
err195
errOAAI
errHu, JM; Flores, D; Toft, D; Wang, XT; Nguyen, D
err分享
err收藏
Molecular chaperones function as steroid receptor nuclear mobility factors
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2004-02-20
err146
errOAAI
errElbi, C; Walker, DA; Romero, G; Sullivan, WP; Toft, DO; Hager, GL; DeFranco, DB
err分享
err收藏
Interaction of the Hsp90 cochaperone cyclophilin 40 with Hsc70
errCELL STRESS & CHAPERONES
IF3.2
err2004-01-01
err59
errOAAI
errCarrello, A; Allan, RK; Morgan, SL; Owen, BAL; Mok, D; Ward, BK; Minchin, RF; Toft, DO; Ratajczak, T
err分享
err收藏
Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2003-12-01
err172
errOAAI
errArlander, SJH; Eapen, AK; Vroman, BT; McDonald, RJ; Toft, DO; Karnitz, LM
err分享
err收藏
P23, a simple protein with complex activities
errCELL STRESS & CHAPERONES
IF3.2
err2003-01-01
err118
errOAAI
errFelts, SJ; Toft, DO
err分享
err收藏
HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2002-04-01
err140
errOAAI
errHernández, MP; Chadli, A; Toft, DO
err分享
err收藏

研究方向

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