From the Promiscuous Asenapine to Potent Fluorescent Ligands Acting at a Series of Aminergic G-Protein-Coupled ReceptorsJOURNAL OF MEDICINAL CHEMISTRYIF6.82017-12-2213PREAI
Design, synthesis and biological characterization of a new class of osteogenic (1H)-quinolone derivativesEUROPEAN JOURNAL OF MEDICINAL CHEMISTRYIF5.92016-10-0114PREAI
Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathwaySCIENTIFIC REPORTSIF3.92016-03-2429OAAI
MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptorFASEB JOURNALIF4.22015-01-3058OAAI
Time-Resolved FRET Binding Assay to Investigate Hetero-Oligomer Binding Properties: Proof of Concept with Dopamine D1/D3 HeterodimerACS CHEMICAL BIOLOGYIF3.82014-11-1140PREAI
Diastereoselective synthesis of novel aza-diketopiperazines via a domino cyclohydrocarbonylation/addition processCHEMICAL COMMUNICATIONSIF4.22014-01-0112OAAI
Discovery, Molecular and Pharmacological Characterization of GSA-10, a Novel Small-Molecule Positive Modulator of SmoothenedMOLECULAR PHARMACOLOGYIF32013-05-0137PREAI
Stereoselective Multicomponent Assembly of Enantiopure Oxazolopiperidines and -azepinesJOURNAL OF ORGANIC CHEMISTRYIF3.62012-02-1318PREAI
Acylthiourea, Acylurea, and Acylguanidine Derivatives with Potent Hedgehog Inhibiting ActivityJOURNAL OF MEDICINAL CHEMISTRYIF6.82012-02-1088PREAI
Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in miceJOURNAL OF CLINICAL INVESTIGATIONIF13.62011-05-02348OA
Cyclohydrocarbonylation-Based Strategy toward Poly- Substituted PiperidinesORGANIC LETTERSIF52011-04-0446PREAI
Identification and Mechanism of Action of the Acylguanidine MRT-83, a Novel Potent Smoothened AntagonistMOLECULAR PHARMACOLOGYIF32011-03-0134PREAI
Hydroformylation of Alkenylamines. Concise Approaches toward Piperidines, Quinolizidines, and Related AlkaloidsJOURNAL OF ORGANIC CHEMISTRYIF3.62010-11-1756PRE
Virtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsMOLECULAR PHARMACOLOGYIF32010-10-0145PREAI
Short Access to (+)-Lupinine and (+)-Epiquinamide via Double HydroformylationORGANIC LETTERSIF52009-12-2866PREAI
Hydroformylation of Homoallylic Azides: A Rapid Approach toward AlkaloidsORGANIC LETTERSIF52008-12-1562PREAI
A General Approach to Aza-Heterocycles by Means of Domino Sequences Driven by HydroformylationCHEMISTRY-A EUROPEAN JOURNALIF3.72008-12-0141PREAI
Rhodium-catalyzed cyclohydrocarbonylation approach to the syntheses of enantiopure homokainoidsJOURNAL OF ORGANIC CHEMISTRYIF3.62007-11-1424PREAI