未登录Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
Desmoulin, Sita Kugel; Wang, Lei; Polin, Lisa; White, Kathryn; Kushner, Juiwanna; Stout, Mark; Hou, Zhanjun; Cherian, Christina; Gangjee, Aleem; Matherly, Larry H. .png)
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收藏Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporterCherian, Christina; Desmoulin, Sita Kugel; Wang, Lei; Polin, Lisa; White, Kathryn; Kushner, Juiwanna; Stout, Mark; Hou, Zhanjun; Gangjee, Aleem; Matherly, Larry H. 分享 收藏 The impact of the reduced folate carrier on the collateral sensitivity of novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolates with selective uptake by the proton-coupled folate transporterDesmoulin, Sita Kugel; Wang, Lei; Polin, Lisa; White, Kathryn; Kushner, Juiwanna; Stout, Mark; Hou, Zhanjun; Cherian, Christina; Gangjee, Aleem; Matherly, Larry H. 分享 收藏 Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate TransporterDesmoulin, Sita Kugel; Wang, Lei; Hales, Eric; Polin, Lisa; White, Kathryn; Kushner, Juiwanna; Stout, Mark; Hou, Zhanjun; Cherian, Christina; Gangjee, Aleem; Matherly, Larry H. 分享 收藏 Synthesis, Biological, and Antitumor Activity of a Highly Potent 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolate Inhibitor with Proton-Coupled Folate Transporter and Folate Receptor Selectivity over the Reduced Folate Carrier That Inhibits β-Glycinamide Ribonucleotide FormyltransferaseWang, Lei; Desmoulin, Sita Kugel; Cherian, Christina; Polin, Lisa; White, Kathryn; Kushner, Juiwanna; Fulterer, Andreas; Chang, Min-Hwang; Mitchell-Ryan, Sherrnaine; Stout, Mark; Romero, Michael F.; Hou, Zhanjun; Matherly, Larry H.; Gangjee, Aleem 分享 收藏 分享 收藏 Mechanisms of Synergistic Antileukemic Interactions between Valproic Acid and Cytarabine in Pediatric Acute Myeloid LeukemiaXie, Chengzhi; Edwards, Holly; Xu, Xuelian; Zhou, Hui; Buck, Steven A.; Stout, Mark L.; Yu, Qun; Rubnitz, Jeffrey E.; Matherly, Larry H.; Taub, Jeffrey W.; Ge, Yubin 分享 收藏 Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid TumorsDesmoulin, Sita Kugel; Wang, Yiqiang; Wu, Jianmei; Stout, Mark; Hou, Zhanjun; Fulterer, Andreas; Chang, Min-Hwang; Romero, Michael F.; Cherian, Christina; Gangjee, Aleem; Matherly, Larry H. 分享 收藏 分享 收藏 
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