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收藏TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody, favors tumor regression via profound immune remodeling of the tumor microenvironmentTG6050是一种编码interleukin-12和anti-CTLA-4抗体的溶瘤痘苗病毒，通过对肿瘤微环境进行深刻的免疫重塑来促进肿瘤消退。
Azar, Fadi; Deforges, Jules; Demeusoit, Christelle; Kleinpeter, Patricia; Remy, Christelle; Silvestre, Nathalie; Foloppe, Johann; Fend, Laetitia; Spring-Giusti, Clementine; Quemeneur, Eric; Marchand, Jean-Baptiste 分享 收藏 分享 收藏 Oncolytic virotherapy with intratumoral injection of vaccinia virus TG6002 and 5-fluorocytosine administration in dogs with malignant tumorsBeguin, Jeremy; Laloy, Eve; Cochin, Sandrine; Gantzer, Murielle; Farine, Isabelle; Pichon, Christelle; Moreau, Baptiste; Foloppe, Johann; Balloul, Jean-Marc; Machon, Christelle; Tierny, Dominique; Klonjkowski, Bernard; Quemeneur, Eric; Maurey, Christelle; Erbs, Philippe 分享 收藏 PoxSTG, a novel chimeric poxvirus with improved oncolytic potencyErbs, Philippe; Findeli, Annie; Foloppe, Johann; Kempf, Juliette; Farine, Isabelle; Moreau, Baptiste; Hortelano, Julie; Pichon, Christelle; Deforges, Jules; Quemeneur, Eric 分享 收藏 AZD4820 ONCOLYTIC VACCINIA VIRUS ENCODING IL-12 MEDIATES ANTI-TUMOR ACTIVITY THROUGH ONCOLYSIS AND TUMOR-SPECIFIC IMMUNITYKurokawa, Cheyne; Agrawal, Sonia; Mitra, Abhisek; Galvani, Elena; Burke, Shannon; Varshine, Ankita; Rothstein, Raymond; Foloppe, Johann; Silvestre, Nathalie; Quemeneur, Eric; Sapra, Puja; Barrett, Carl; Hammond, Scott; Laliberte, Jason; Durham, Nicholas; Oberst, Michael; Broggi, Maria 分享 收藏 Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject 'cold' tumorsSemmrich, Monika; Marchand, Jean-Baptiste; Fend, Laetitia; Rehn, Matilda; Remy, Christelle; Holmkvist, Petra; Silvestre, Nathalie; Svensson, Carolin; Kleinpeter, Patricia; Deforges, Jules; Junghus, Fred; Cleary, Kirstie L.; Boden, Mimoza; Martensson, Linda; Foloppe, Johann; Teige, Ingrid; Quemeneur, Eric; Frendeus, Bjorn 分享 收藏 VECTORIZED TREG-DEPLETING ANTI-CTLA-4 ELICITS ANTIGEN CROSS-PRESENTATION AND CD8+T CELL IMMUNITY TO REJECT COLD TUMORSSemmrich, Monika; Marchand, Jean-Baptiste; Rehn, Matilda; Fend, Laetitia; Remy-Ziller, Christelle; Holmkvist, Petra; Silvestre, Nathalie; Svensson, Carolin; Kleinpeter, Patricia; Deforges, Jules; Junghus, Fred; Martensson, Linda; Foloppe, Johann; Teige, Ingrid; Quemeneur, Eric; Frendeus, Bjorn 分享 收藏 分享 收藏 Preclinical Evaluation of the Oncolytic Vaccinia Virus TG6002 by Translational Research on Canine Breast CancerBeguin, Jeremy; Foloppe, Johann; Maurey, Christelle; Laloy, Eve; Hortelano, Julie; Nourtier, Virginie; Pichon, Christelle; Cochin, Sandrine; Cordier, Pascale; Huet, Helene; Quemeneur, Eric; Klonjkowski, Bernard; Erbs, Philippe 分享 收藏 Fluorescent Tagged Vaccinia Virus Genome Allows Rapid and Efficient Measurement of Oncolytic Potential and Discovery of Oncolytic ModulatorsGallardo, Franck; Schmitt, Doris; Brandely, Renee; Brua, Catherine; Silvestre, Nathalie; Findeli, Annie; Foloppe, Johann; Top, Sokunthea; Kappler-Gratias, Sandrine; Quentin-Froignant, Charlotte; Morin, Renaud; Lagarde, Jean-Michel; Bystricky, Kerstin; Bertagnoli, Stephane; Erbs, Philippe 分享 收藏 BT-001, AN ONCOLYTIC VACCINIA VIRUS ARMED WITH A TREG-DEPLETING HUMAN RECOMBINANT ANTI-CTLA4 ANTIBODY AND GM-CSF TO TARGET THE TUMOR MICROENVIRONMENTSemmrich, Monika; Marchand, Jean-Baptiste; Fend, Laetitia; Rehn, Matilda; Silvestre, Nathalie; Martensson, Linda; Foloppe, Johann; Teige, Ingrid; Quemeneur, Eric; Frendeus, Bjorn 分享 收藏 High Oncolytic Activity of a Double-Deleted Vaccinia Virus Copenhagen Strain against Malignant Pleural MesotheliomaDelaunay, Tiphaine; Nader, Joelle; Grard, Marion; Farine, Isabelle; Hedwig, Vera; Foloppe, Johann; Blondy, Thibaut; Violland, Mathilde; Pouliquen, Daniel; Gregoire, Marc; Boisgerault, Nicolas; Erbs, Philippe; Fonteneau, Jean-Francois 分享 收藏 Oncolytic vaccinia virus TG6010 expressing cytidine deaminase induces DNA damage and shows potent anti-tumor effectsFoloppe, Johann; Kempf, Juliette; Pichon, Christelle; Findeli, Annie; Farine, Isabelle; Hortelano, Julie; Moreau, Baptiste; Klein, Michele; Cochin, Sandrine; Brandely, Renee; Koerper, Veronique; Silvestre, Nathalie; Machon, Christelle; Guitton, Jerome; Quemeneur, Eric; Erbs, Philippe 分享 收藏 BT-001, an oncolytic vaccinia virus armed with a Treg-depletion-optimized recombinant human anti-CTLA4 antibody and GM-CSF to target the tumor microenvironmentMarchand, Jean-Baptiste; Semmrich, Monika; Fend, Laetitia; Rehn, Matilda; Silvestre, Nathalie; Teige, Ingrid; Foloppe, Johann; Martensson, Linda; Quemeneur, Eric; Frendeus, Bjorn 分享 收藏 The Enhanced Tumor Specificity of TG6002, an Armed Oncolytic Vaccinia Virus Deleted in Two Genes Involved in Nucleotide MetabolismFoloppe, Johann; Kempf, Juliette; Futin, Nicolas; Kintz, Jacqueline; Cordier, Pascale; Pichon, Christelle; Findeli, Annie; Vorburger, Fabien; Quemeneur, Eric; Erbs, Philippe 分享 收藏 Deletion of Apoptosis Inhibitor F1L in Vaccinia Virus Increases Safety and Oncolysis for Cancer TherapyPelin, Adrian; Foloppe, Johann; Petryk, Julia; Singaravelu, Ragunath; Hussein, Marian; Gossart, Florian; Jennings, Victoria A.; Stubbert, Lawton J.; Foster, Madison; Storbeck, Christopher; Postigo, Antonio; Scut, Elena; Laight, Brian; Way, Michael; Erbs, Philippe; Le Boeuf, Fabrice; Bell, John C. 分享 收藏 Characterization, evaluation and safety studies of the oncolytic Vaccinia virus TG6002 for canine cancer therapyBeguin, Jeremy; Foloppe, Johann; Laloy, Eve; Nourtier, Virginie; Farine, Isabelle; Gantzer, Murielle; Pichon, Christelle; Cochin, Sandrine; Cordier, Pascale; Tierny, Dominique; Balloul, Jean Marc; Quemeneur, Eric; Maurey, Christelle; Klonjkowski, Bernard; Erbs, Philippe 分享 收藏 By Binding CD80 and CD86, the Vaccinia Virus M2 Protein Blocks Their Interactions with both CD28 and CTLA4 and Potentiates CD80 Binding to PD-L1通过结合CD80和CD86，痘苗病毒M2蛋白阻断它们与CD28和CTLA4的相互作用，并增强CD80与PD-L1的结合。Kleinpeter, Patricia; Remy-Ziller, Christelle; Winter, Eline; Gantzer, Murielle; Nourtier, Virginie; Kempf, Juliette; Hortelano, Julie; Schmitt, Doris; Schultz, Huguette; Geist, Michel; Brua, Catherine; Hoffmann, Chantal; Schlesinger, Yasmin; Villeval, Dominique; Thioudellet, Christine; Erbs, Philippe; Foloppe, Johann; Silvestre, Nathalie; Fend, Laetitia; Quemeneur, Eric; Marchand, Jean-Baptiste 分享 收藏 Pseudocowpox: A next generation viral vector for cancer immunotherapyRittner, Karola; Ricordel, Marine; Tosch, Caroline; Thioudellet, Christine; Remy-Ziller, Christelle; Claudepierre, Marie-Christine; Hoffmann, Chantal; Schmitt, Doris; Sansas, Benoit; Foloppe, Johann; Erbs, Philippe; Silvestre, Nathalie; Bendjama, Kaidre; Quemeneur, Eric 分享 收藏 
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