未登录 Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitors 6-吡啶基甲基氨基嘌呤类CDK抑制剂的设计、合成及生物活性评价 Wilson, Stuart C.; Atrash, Butrus; Barlow, Clare; Eccles, Susan; Fischer, Peter M.; Hayes, Angela; Kelland, Lloyd; Jackson, Wayne; Jarman, Michael; Mirza, Amin; Moreno, Javier; Nutley, Bernard P.; Raynaud, Florence I.; Sheldrake, Peter; Walton, Mike; Westwood, Robert; Whittaker, Steven; Workman, Paul; McDonald, Edward 分享 收藏
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Guidelines for the welfare and use of animals in cancer research Workman, P.; Aboagye, E. O.; Balkwill, F.; Balmain, A.; Bruder, G.; Chaplin, D. J.; Double, J. A.; Everitt, J.; Farningham, D. A. H.; Glennie, M. J.; Kelland, L. R.; Robinson, V.; Stratford, I. J.; Tozer, G. M.; Watson, S.; Wedge, S. R.; Eccles, S. A.; Navaratnam, V.; Ryder, S. 分享 收藏
A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo 一种新型蛋白激酶D小分子抑制剂在体内外阻断胰腺癌生长 Harikumar, Kuzhuvelil B.; Kunnumakkara, Ajaikumar B.; Ochi, Nobuo; Tong, Zhimin; Deorukhkar, Amit; Sung, Bokyung; Kelland, Lloyd; Jamieson, Stephen; Sutherland, Rachel; Raynham, Tony; Charles, Mark; Bagherzadeh, Azadeh; Foxton, Caroline; Boakes, Alexandra; Farooq, Muddasar; Maru, Dipen; Diagaradjane, Parmeswaran; Matsuo, Yoichi; Sinnett-Smith, James; Gelovani, Juri; Krishnan, Sunil; Aggarwal, Bharat B.; Rozengurt, Enrique; Ireson, Christopher R.; Guha, Sushovan 分享 收藏
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Pharmacologic characterization of a potent inhibitor of class I phosphatidylinositide 3-kinases Raynaud, Florence I.; Eccles, Suzanne; Clarke, Paul A.; Hayes, Angela; Nutley, Bernard; Alix, Sonia; Henley, Alan; Di-Stefano, Francesca; Ahmad, Zahida; Guillard, Sandrine; Bjerke, Lynn M.; Kelland, Lloyd; Valenti, Melanie; Patterson, Lisa; Gowan, Sharon; Brandon, Alexis de Haven; Hayakawa, Masahiko; Kaizawa, Hiroyuki; Koizumi, Tomonubu; Ohishi, Takahide; Patel, Sonal; Saghir, Nahid; Parker, Peter; Waterfield, Mike; Workman, Paul 分享 收藏
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Rat tumor response to the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid as measured by dynamic contrast-enhanced magnetic resonance imaging, plasma 5-hydroxyindoleacetic acid levels, and tumor necrosis McPhail, Lesley D.; McIntyre, Dominick J. O.; Ludwig, Christian; Kestell, Philip; Griffiths, John R.; Kelland, Lloyd R.; Robinson, Simon P. 分享 收藏
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Preclinical pharmacokinetics and metabolism of a novel prototype DNA-PK inhibitor NU7026 Nutley, BP; Smith, NF; Hayes, A; Kelland, LR; Brunton, L; Golding, BT; Smith, GCM; Martin, NMB; Workman, P; Raynaud, FI 分享 收藏
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In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202 Raynaud, FI; Whittaker, SR; Fischer, PM; McClue, S; Walton, MI; Barrie, SE; Garrett, MD; Rogers, P; Clarke, SJ; Kelland, LR; Valenti, M; Brunton, L; Eccles, S; Lane, DP; Workman, P 分享 收藏
Tumor dose response to the vascular disrupting agent, 5,6-dimethylxanthenone-4-acetic acid, using in vivo magnetic resonance spectroscopy McPhail, LD; Chung, YL; Madhu, B; Clark, S; Griffiths, JR; Kelland, LR; Robinson, SP 分享 收藏
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SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity.: Part 1:: Cellular pharmacology, in vitro and initial in vivo antitumor activity Hartley, JA; Spanswick, VJ; Brooks, N; Clingen, PH; McHugh, PJ; Hochhauser, D; Pedley, RB; Kelland, LR; Alley, MC; Schultz, R; Hollingshead, MG; Schweikart, KM; Tomaszewski, JE; Sausville, EA; Gregson, SJ; Howard, PW; Thurston, DE 分享 收藏
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