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M

Masahiko Negishi

National Institutes of Health

107H指数
661论文数
4.0W被引数
收录论文 25
发表时间
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Mutation of PXR phosphorylation motif at Ser347 disrupts lipid and bile acid homeostasis in diet-induced metabolic dysfunction–associated steatohepatitis in mice
errDrug Metabolism and Disposition
IF4
err2025-12-22
err0
errOAAI
errVeronia Basaly; Zakiyah R. Henry; Rulaiha E. Taylor; Bo Kong; Ill Yang; Anita Brinker; Zhenning Yang; Peihong Zhou; Laurie B. Joseph; Lauren Aleksunes; Brian Buckley; Masahiko Negishi; Grace L. Guo
err分享
err收藏
The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err718
errOAAI
errHonkakoski, P; Zelko, I; Sueyoshi, T; Negishi, M
err分享
err收藏
Human constitutive androstane receptor represses liver cancer development and hepatoma cell proliferation by inhibiting erythropoietin signaling
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-05-01
err18
errOAAI
errLi, Zhihu; Kwon, So Mee; Li, Daochuan; Li, Linhao; Peng, Xiwei; Zhang, Junran; Sueyoshi, Tatsuya; Raufman, Jean-Pierre; Negishi, Masahiko; Wang, Xin Wei; Wang, Hongbing
err分享
err收藏
Androgen receptor phosphorylated at Ser815: The expression and function in the prostate and tumor-derived cells
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2021-12-01
err8
PREAI
errYokobori, Kosuke; Kawasaki, Yuki; Sekine, Yoshitaka; Nobusawa, Sumihito; Sakaki, Toshiyuki; Negishi, Masahiko; Kakizaki, Satoru
err分享
err收藏
Sex-specific expression mechanism of hepatic estrogen inactivating enzyme and transporters in diabetic women
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2021-08-01
err8
errOAAI
errFashe, Muluneh; Yi, MyeongJin; Sueyoshi, Tatsuya; Negishi, Masahiko
err分享
err收藏
Estrogen Sulfotransferase (SULT1E1): Its Molecular Regulation, Polymorphisms, and Clinical Perspectives
errJOURNAL OF PERSONALIZED MEDICINE
IF3
err2021-03-11
err28
errOAAI
errYi, MyeongJin; Negishi, Masahiko; Lee, Su-Jun
err分享
err收藏
RORα phosphorylation by casein kinase 1α as glucose signal to regulate estrogen sulfation in human liver cells
errBIOCHEMICAL JOURNAL
IF4.3
err2020-09-28
err5
errOAAI
errHu, Hao; Negishi, Masahiko
err分享
err收藏
Phosphorylation of vaccinia-related kinase 1 at threonine 386 transduces glucose stress signal in human liver cells
errBIOSCIENCE REPORTS
IF4.7
err2020-04-23
err6
errOAAI
errYokobori, Kosuke; Miyauchi, Yuu; Williams, Jason G.; Negishi, Masahiko
err分享
err收藏
Ligand induced dissociation of the AR homodimer precedes AR monomer translocation to the nucleus
errSCIENTIFIC REPORTS
IF3.9
err2019-11-13
err13
errOAAI
errShizu, Ryota; Yokobori, Kosuke; Perera, Lalith; Pedersen, Lee; Negishi, Masahiko
err分享
err收藏
A phosphorylation-deficient mutant of retinoid X receptor α at Thr 167 alters fasting response and energy metabolism in mice
errLABORATORY INVESTIGATION
IF4.2
err2019-10-01
err9
errOAAI
errSueyoshi, Tatsuya; Sakuma, Tsutomu; Shindo, Sawako; Fashe, Muluneh; Kanayama, Tomohiko; Ray, Manas; Moore, Rick; Negishi, Masahiko
err分享
err收藏
Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver
errMOLECULAR CANCER RESEARCH
IF4.7
err2018-07-31
err19
errOAAI
errHori, Takeshi; Saito, Kosuke; Moore, Rick; Flake, Gordon P.; Negishi, Masahiko
err分享
err收藏
Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase gene
errBIOCHEMICAL JOURNAL
IF4.3
err2007-10-12
err128
errOAAI
errKodama, Susumu; Moore, Rick; Yamamoto, Yukio; Negishi, Masahiko
err分享
err收藏
Cohesin protein SMC1 represses the nuclear receptor CAR-mediated synergistic activation of a human P450 gene by xenobiotics
errBIOCHEMICAL JOURNAL
IF4.3
err2006-07-27
err16
errOAAI
errInoue, Kaoru; Borchers, Christoph H.; Negishi, Masahiko
err分享
err收藏
Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2006-06-01
err179
PREAI
errFaucette, Stephanie R.; Sueyoshi, Tatsuya; Smith, Cornelia M.; Negishi, Masahiko; LeCluyse, Edward L.; Wang, Hongbing
err分享
err收藏
Serine 202 regulates the nuclear translocation of constitutive active/androstane receptor
errMOLECULAR PHARMACOLOGY
IF3
err2006-04-01
err73
PREAI
errHosseinpour, F; Moore, R; Negishi, M; Sueyoshi, T
err分享
err收藏
Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 cells
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2005-12-01
err44
PREAI
errSmith, CM; Graham, RA; Krol, WL; Silver, IS; Negishi, M; Wang, HB; Lecluyse, EL
err分享
err收藏
The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4α to synergistically activate the human CYP2C9 promoter
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2005-09-01
err104
PREAI
errChen, YP; Kissling, G; Negishi, M; Goldstein, JA
err分享
err收藏
Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4α
errMOLECULAR PHARMACOLOGY
IF3
err2005-09-01
err185
PREAI
errFerguson, SS; Chen, YP; LeCluyse, EL; Negishi, M; Goldstein, JA
err分享
err收藏
Thr176 regulates the activity of the mouse nuclear receptor CAR and is conserved in the NR1I subfamily members PXR and VDR
errBIOCHEMICAL JOURNAL
IF4.3
err2005-05-24
err16
errOAAI
errUeda, A; Matsui, K; Yamamoto, Y; Pedersen, LC; Sueyoshi, T; Negishi, M
err分享
err收藏
The constitutive active/androstane receptor regulates phenytoin induction of Cyp2c29
errMOLECULAR PHARMACOLOGY
IF3
err2004-06-01
err52
PREAI
errJackson, JP; Ferguson, SS; Moore, R; Negishi, M; Goldstein, JA
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
P
Peter G. Schultz
H 指数: 159 · 论文数: 880
N
Nathanael S. Gray
H 指数: 145 · 论文数: 1.5K
C
Carolyn R. Bertozzi
H 指数: 140 · 论文数: 942
X
Xin Wei Wang
H 指数: 105 · 论文数: 675
L
L. Perera
H 指数: 90 · 论文数: 488
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