Francesco Berardi - Publications, H-index & Citations

Francesco Berardi

universita degli studi di bari aldo moro

40H指数

297论文数

5.3K被引数

收录论文 97

发表时间

Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ1) receptor ligands with potent anti-amnesic effect

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-01-01

PREAI

Abatematteo, Francesca S.; Mosier, Philip D.; Niso, Mauro; Brunetti, Leonardo; Berardi, Francesco; Loiodice, Fulvio; Contino, Marialessandra; Delprat, Benjamin; Maurice, Tangui; Laghezza, Antonio; Abate, Carmen

Multifunctional thiosemicarbazones targeting sigma receptors: in vitro and in vivo antitumor activities in pancreatic cancer models

CELLULAR ONCOLOGY

IF4.8

2021-09-29

OAAI

Niso, Mauro; Kopecka, Joanna; Abatematteo, Francesca Serena; Berardi, Francesco; Riganti, Chiara; Abate, Carmen

Why PB28 Could Be a Covid 2019 Game Changer?

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2020-08-14

OAAI

Colabufo, Nicola Antonio; Leopoldo, Marcello; Ferorelli, Savina; Abate, Carmen; Contino, Marialessandra; Perrone, Maria Grazia; Niso, Mauro; Perrone, Roberto; Berardi, Francesco

High-affinity sigma-1 (σ1) receptor ligands based on the σ1 antagonist PB212 基于 σ1拮抗剂PB212的高亲和力sigma-1 (σ1) 受体配体

FUTURE MEDICINAL CHEMISTRY

IF3.4

2019-10-21

PREAI

Niso, Mauro; Mosier, Philip D.; Marottoli, Roberta; Ferorelli, Savina; Cassano, Giuseppe; Gasparre, Giuseppe; Leopoldo, Marcello; Berardi, Francesco; Abate, Carmen

Sigma-2 receptor: past, present and perspectives on multiple therapeutic exploitations

FUTURE MEDICINAL CHEMISTRY

IF3.4

2018-07-03

PREAI

Abate, Carmen; Niso, Mauro; Berardi, Francesco

Multifunctional thiosemicarbazones and deconstructed analogues as a strategy to study the involvement of metal chelation, Sigma-2 (σ2) receptor and P-gp protein in the cytotoxic action: In vitro and in vivo activity in pancreatic tumors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-01-01

OAAI

Pati, Maria Laura; Niso, Mauro; Spitzer, Dirk; Berardi, Francesco; Contino, Marialessandra; Riganti, Chiara; Hawkins, William G.; Abate, Carmen

The σ1 receptor agonist (+)-pentazocine increases store-operated Ca2+ entry in MCF7σ1 and SK-N-SH cell lines

PHARMACOLOGICAL REPORTS

IF3.8

2017-06-01

PREAI

Gasparre, Giuseppe; Abate, Carmen; Carlucci, Roberto; Berardi, Francesco; Cassano, Giuseppe

Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1

PHARMACOLOGICAL RESEARCH

IF10.5

2017-03-01

OAAI

Pati, Maria Laura; Groza, Diana; Riganti, Chiara; Kopecka, Joanna; Niso, Mauro; Berardi, Francesco; Hager, Sonja; Heffeter, Petra; Hirai, Miwa; Tsugawa, Hitoshi; Kabe, Yasuaki; Suematsu, Makoto; Abate, Carmen

Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer

BMC CANCER

IF3.4

2017-01-13

OAAI

Pati, Maria Laura; Hornick, John R.; Niso, Mauro; Berardi, Francesco; Spitzer, Dirk; Abate, Carmen; Hawkins, William

Development of sigma-1 (σ1) receptor fluorescent ligands as versatile tools to study σ1 receptors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2016-01-01

OAAI

Abate, Carmen; Riganti, Chiara; Pati, Maria Laura; Ghigo, Dario; Berardi, Francesco; Mavlyutov, Timur; Guo, Lian-Wang; Ruoho, Arnold

Elements in support of the 'non-identity' of the PGRMC1 protein with the σ2 receptor

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2015-07-01

PREAI

Abate, Carmen; Niso, Mauro; Infantino, Vittoria; Menga, Alessio; Berardi, Francesco

Synthesis and pharmacological evaluation of 11C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging

NUCLEAR MEDICINE AND BIOLOGY

IF3

2015-04-01

PREAI

Selivanova, Svetlana V.; Toscano, Annamaria; Abate, Carmen; Berardi, Francesco; Mueller, Adrienne; Kraemer, Stefanie D.; Schibli, Roger; Ametamey, Simon M.

From mixed sigma-2 receptor/P-glycoprotein targeting agents to selective P-glycoprotein modulators: Small structural changes address the mechanism of interaction at the efflux pump

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2015-01-01

PREAI

Abate, Carmen; Pati, Maria Laura; Contino, Marialessandra; Colabufo, Nicola Antonio; Perrone, Roberto; Niso, Mauro; Berardi, Francesco

Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate P-glycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2015-01-01

PREAI

Pati, Maria Laura; Abate, Carmen; Contino, Marialessandra; Ferorelli, Savina; Luisi, Renzo; Carroccia, Laura; Niso, Mauro; Berardi, Francesco

SAR Studies on Tetrahydroisoquinoline Derivatives: The Role of Flexibility and Bioisosterism To Raise Potency and Selectivity toward P-glycoprotein

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-11-20

PREAI

Capparelli, Elena; Zinzi, Laura; Cantore, Mariangela; Contino, Marialessandra; Perrone, Maria Grazia; Luurtsema, Gert; Berardi, Francesco; Perrone, Roberto; Colabufo, Nicola A.

Trimethoxybenzanilide-Based P-Glycoprotein Modulators: An Interesting Case of Lipophilicity Tuning by Intramolecular Hydrogen Bonding

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-08-05

PREAI

Tardia, Piero; Stefanachi, Angela; Niso, Mauro; Stolfa, Diana Antonella; Mangiatordi, Giuseppe Felice; Alberga, Domenico; Nicolotti, Orazio; Lattanzi, Gianluca; Carotti, Angelo; Leonetti, Francesco; Perrone, Roberto; Berardi, Francesco; Azzariti, Amalia; Colabufo, Nicola Antonio; Cellamare, Saverio

Synthesis, radiolabeling and in vivo evaluation of [11C](R)-1-[4-[2-(4-methoxyphenyl)phenyl piperazin-1-yl]-3-(2-pyrazinyloxy)-2-propanol, a potential PET radioligand for the 5-HT7 receptor

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2014-05-01

PREAI

Hansen, Hanne D.; Lacivita, Enza; Di Pilato, Pantaleo; Herth, Matthias M.; Lehel, Szabolcs; Ettrup, Anders; Andersen, Valdemar L.; Dyssegaard, Agnete; De Giorgio, Paola; Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola Antonio; Niso, Mauro; Knudsen, Gitte M.; Leopoldo, Marcello

Novel Derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Improved Fluorescent and a Receptors Binding Properties

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-04-14

PREAI

Abate, Carmen; Niso, Mauro; Marottoli, Roberta; Riganti, Chiara; Ghigo, Dario; Ferorelli, Savina; Ossato, Giulia; Perrone, Roberto; Lacivita, Enza; Lamb, Don C.; Berardi, Francesco

The effects of new sigma (σ) receptor ligands, PB190 and PB212, in the models predictive of antidepressant activity

PHARMACOLOGICAL REPORTS

IF3.8

2014-04-01

PREAI

Skuza, Grazyna; Sadaj, Witold; Kabzinski, Marcin; Cassano, Giuseppe; Gasparre, Giuseppe; Abate, Carmen; Berardi, Francesco

Selective agonists for serotonin 7 (5-HT7) receptor and their applications in preclinical models: an overview

REVIEWS IN THE NEUROSCIENCES

IF4.1

2014-03-13

PREAI

Di Pilato, Pantaleo; Niso, Mauro; Adriani, Walter; Romano, Emilia; Travaglini, Domenica; Berardi, Francesco; Colabufo, Nicola A.; Perrone, Roberto; Laviola, Giovanni; Lacivita, Enza; Leopoldo, Marcello

研究方向