未登录 Taming hemoglobin chemistry-a new hemoglobin-based oxygen carrier engineered with both decreased rates of nitric oxide scavenging and lipid oxidation Cooper, Chris E.; Simons, Michelle; Dyson, Alex; Eriksson, Nelida Leiva; Silkstone, Gary G. A.; Syrett, Natalie; Allen-Baume, Victoria; Buelow, Leif; Ronda, Luca; Mozzarelli, Andrea; Singer, Mervyn; Reeder, Brandon J. 分享 收藏
Stability of Maleimide-PEG and Mono-Sulfone-PEG Conjugation to a Novel Engineered Cysteine in the Human Hemoglobin Alpha Subunit 马来酰亚胺-PEG和单砜-PEG与人血红蛋白 α 亚基中新的工程半胱氨酸缀合的稳定性 Cooper, Chris E.; Bird, Matthew; Sheng, XiaoBo; Choi, Ji-Won; Silkstone, Gary G. A.; Simons, Michelle; Syrett, Natalie; Piano, Riccardo; Ronda, Luca; Bettati, Stefano; Paredi, Gianluca; Mozzarelli, Andrea; Reeder, Brandon J. 分享 收藏
Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality Cooper, Chris E.; Silkstone, Gary G. A.; Simons, Michelle; Gretton, Svetlana; Rajagopal, Badri S.; Allen-Baume, Victoria; Syrett, Natalie; Shaik, Thoufieq; Popa, Gina; Sheng, XiaoBo; Bird, Matthew; Choi, Ji-Won; Piano, Riccardo; Ronda, Luca; Bettati, Stefano; Paredi, Gianluca; Mozzarelli, Andrea; Reeder, Brandon J. 分享 收藏
Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute 将酪氨酸残基工程化为血红蛋白可增强血红素的减少，减少氧化应激并增加基于血红蛋白的血液替代品的血管保留 Cooper, Chris E.; Silkstone, Gary G. A.; Simons, Michelle; Rajagopal, Badri; Syrett, Natalie; Shaik, Thoufieq; Gretton, Svetlana; Welbourn, Elizabeth; Bulow, Leif; Eriksson, Nelida Leiva; Ronda, Luca; Mozzarelli, Andrea; Eke, Andras; Mathe, Domokos; Reeder, Brandon J. 分享 收藏
Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers Simons, Michelle; Gretton, Svetlana; Silkstone, Gary G. A.; Rajagopal, Badri S.; Allen-Baume, Victoria; Syrett, Natalie; Shaik, Thoufieq; Leiva-Eriksson, Nelida; Ronda, Luca; Mozzarelli, Andrea; Strader, Michael B.; Alayash, Abdu I.; Reeder, Brandon J.; Cooper, Chris E. 分享 收藏
Location of the Retinal Chromophore in the Activated State of Rhodopsin Ahuja, Shivani; Crocker, Evan; Eilers, Markus; Hornak, Viktor; Hirshfeld, Amiram; Ziliox, Martine; Syrett, Natalie; Reeves, Philip J.; Khorana, H. Gobind; Sheves, Mordechai; Smith, Steven O. 分享 收藏
Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation Ahuja, Shivani; Hornak, Viktor; Yan, Elsa C. Y.; Syrett, Natalie; Goncalves, Joseph A.; Hirshfeld, Amiram; Ziliox, Martine; Sakmar, Thomas P.; Sheves, Mordechai; Reeves, Philip J.; Smith, Steven O.; Eilers, Markus 分享 收藏
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