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M

Molly M. Hood

swiss institute experimental cancer research
H指数:13
被引数:1,230

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DCC-3084, a brain penetrant RAF dimer inhibitor, broadly inhibits BRAF class I, II, and III alterations leading to growth inhibition of intracranially implanted tumors in preclinical models
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Al-Ani, Gada; Bulfer, Stacie L.; Zwicker, Jefferey D.; Crawley, Chase K.; Elliot, Kristin M.; Javed, Salim; Groer, Qi; Hood, Molly M.; Large, Joshua W.; Luther, Kylie; Romero, Yeni K.; Stanley, Forrest A.; Tanner, Daniel C.; Telikepalli, Hanumaiah; Le Bourdonnec, Bertrand; Smith, Bryan D.; Flynn, Daniel L.
DCC-3084, a RAF dimer inhibitor, broadly inhibits BRAF class I, II, III, BRAF fusions, and RAS-driven solid tumors leading to tumor regression in preclinical models
CANCER RESEARCH
IF16.6
2023-04-042
PRE
Bulfer, Stacie L.; Le Bourdonnec, Bertrand; Zwicker, Jeffery D.; Ahn, Yu Mi; Al-Ani, Gada; Al-Hashimi, Hikmat; Crawley, Chase; Elliott, Kristin M.; Faisal, Saqib; Harned, Andrew M.; Heiniger, Cale L.; Hood, Molly M.; Javed, Salim; Kennedy, Michael; Large, Joshua W.; Leary, Cynthia B.; Lu, Wei-Ping; Luther, Kylie; Petty, Max D.; Picard, Hunter R.; Proto, Justin T.; Romero, Yeni K.; Stanley, Forrest A.; Stoltz, Kristen L.; Tanner, Daniel C.; Telikepalli, Hanumaiah; Timson, Mary J.; Vogeti, Lakshminarayana; Vogeti, Subha; Yang, Sihyung; Zhong, Lexy H.; Smith, Bryan D.; Flynn, Daniel L.
DP-9149, an investigational small molecule modulator of the Integrated Stress Response kinase GCN2, pre-clinically causes solid tumor growth inhibition as a single agent and regression in combination with standard of care agents
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Al-Ani, Gada; Groer, Qi; Elliott, Kristin M.; Rudeen, Aaron J.; Kearney, Patrick C.; Zwicker, Jeffery D.; Ahn, Yu Mi; Bulfer, Stacie L.; Heiniger, Cale L.; Hood, Molly M.; Javid, Salim; Large, Joshua W.; Petty, Max D.; Stoltz, Kristen L.; Le Bourdonnec, Bertrand; Smith, Bryan D.; Flynn, Daniel L.
DP-9024, an investigational small molecule modulator of the Integrated Stress Response kinase PERK, causes B-cell cancer growth inhibition as single agent and in combination with standard-of-care agents
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Al-Ani, Gada; Groer, Qi; Rudeen, Aaron J.; Elliott, Kristin M.; Kearney, Patrick C.; Zwicker, Jeffery D.; Ahn, Yu Mi; Bulfer, Stacie L.; Heiniger, Cale L.; Hood, Molly M.; Javed, Salim; Large, Joshua W.; Petty, Max D.; Stoltz, Kristen L.; Le Bourdonnec, Bertrand; Smith, Bryan D.; Flynn, Daniel L.
The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors
MOLECULAR CANCER THERAPEUTICS
IF5.5
2017-11-01112
OAAI
Harney, Allison S.; Karagiannis, George S.; Pignatelli, Jeanine; Smith, Bryan D.; Kadioglu, Ece; Wise, Scott C.; Hood, Molly M.; Kaufman, Michael D.; Leary, Cynthia B.; Lu, Wei-Ping; Al-Ani, Gada; Chen, Xiaoming; Entenberg, David; Oktay, Maja H.; Wang, Yarong; Chun, Lawrence; De Palma, Michele; Jones, Joan G.; Flynn, Daniel L.; Condeelis, John S.
Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2
MOLECULAR CANCER THERAPEUTICS
IF5.5
2015-09-0263
OAAI
Smith, Bryan D.; Kaufman, Michael D.; Leary, Cynthia B.; Turner, Benjamin A.; Wise, Scott C.; Ahn, Yu Mi; Booth, R. John; Caldwell, Timothy M.; Ensinger, Carol L.; Hood, Molly M.; Lu, Wei-Ping; Patt, Tristan W.; Patt, William C.; Rutkoski, Thomas J.; Samarakoon, Thiwanka; Telikepalli, Hanumaiah; Vogeti, Lakshminarayana; Vogeti, Subha; Yates, Karen M.; Chun, Lawrence; Stewart, Lance J.; Clare, Michael; Flynn, Daniel L.
Discovery of 1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Paradoxical Activation and Activity against BRAF or RAS Mutant Tumor Cells
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2015-05-1285
OAAI
Henry, James R.; Kaufman, Michael D.; Peng, Sheng-Bin; Ahn, Yu Mi; Caldwell, Timothy M.; Vogeti, Lakshminarayana; Telikepalli, Hanumaiah; Lu, Wei-Ping; Hood, Molly M.; Rutkoski, Thomas J.; Smith, Bryan D.; Vogeti, Subha; Miller, David; Wise, Scott C.; Chun, Lawrence; Zhang, Xiaoyi; Zhang, Youyan; Kays, Lisa; Hipskind, Philip A.; Wrobleski, Aaron D.; Lobb, Karen L.; Clay, Julia M.; Cohen, Jeffrey D.; Walgren, Jennie L.; McCann, Denis; Patel, Phenil; Clawson, David K.; Guo, Sherry; Manglicmot, Danalyn; Groshong, Chris; Logan, Cheyenne; Starling, James J.; Flynn, Daniel L.

研究方向

暂未获取到该数据
B
Bryan D. Smith
H 指数:22论文数:137被引数:2,304
D
Daniel L. Flynn
H 指数:35论文数:209被引数:4,237
M
Michael D. Kaufman
H 指数:36论文数:158被引数:5,484
S
Scott Wise
H 指数:22论文数:164被引数:2,529
G
Gada Al-Ani
H 指数:6论文数:41被引数:559
Y
Yu Mi Ahn
H 指数:12论文数:59被引数:1,124
W
Wei-Ping Lu
H 指数:8论文数:25被引数:649
S
Stacie L. Bulfer
H 指数:15论文数:56被引数:1,329
Q
Qi Groer
H 指数:1论文数:12被引数:3
J
Joshua W. Large
H 指数:1论文数:14被引数:6