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科言猫学术研究的AI总结
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J

Joshua W. Large

H指数:1
被引数:6

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DCC-3084, a brain penetrant RAF dimer inhibitor, broadly inhibits BRAF class I, II, and III alterations leading to growth inhibition of intracranially implanted tumors in preclinical models
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Al-Ani, Gada; Bulfer, Stacie L.; Zwicker, Jefferey D.; Crawley, Chase K.; Elliot, Kristin M.; Javed, Salim; Groer, Qi; Hood, Molly M.; Large, Joshua W.; Luther, Kylie; Romero, Yeni K.; Stanley, Forrest A.; Tanner, Daniel C.; Telikepalli, Hanumaiah; Le Bourdonnec, Bertrand; Smith, Bryan D.; Flynn, Daniel L.
DCC-3084, a RAF dimer inhibitor, broadly inhibits BRAF class I, II, III, BRAF fusions, and RAS-driven solid tumors leading to tumor regression in preclinical models
CANCER RESEARCH
IF16.6
2023-04-042
PRE
Bulfer, Stacie L.; Le Bourdonnec, Bertrand; Zwicker, Jeffery D.; Ahn, Yu Mi; Al-Ani, Gada; Al-Hashimi, Hikmat; Crawley, Chase; Elliott, Kristin M.; Faisal, Saqib; Harned, Andrew M.; Heiniger, Cale L.; Hood, Molly M.; Javed, Salim; Kennedy, Michael; Large, Joshua W.; Leary, Cynthia B.; Lu, Wei-Ping; Luther, Kylie; Petty, Max D.; Picard, Hunter R.; Proto, Justin T.; Romero, Yeni K.; Stanley, Forrest A.; Stoltz, Kristen L.; Tanner, Daniel C.; Telikepalli, Hanumaiah; Timson, Mary J.; Vogeti, Lakshminarayana; Vogeti, Subha; Yang, Sihyung; Zhong, Lexy H.; Smith, Bryan D.; Flynn, Daniel L.
Pan-exon mutant KIT inhibitor DCC-3009 demonstrates tumor regressions in preclinical gastrointestinal stromal tumor models
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Smith, Bryan D.; Vogeti, Subha; Caldwell, Timothy M.; Telikepalli, Hanumaiah; Ahn, Yu Mi; Al-Ani, Gada; Bulfer, Stacie L.; Greenwood, Andrew; Heiniger, Cale L.; Large, Joshua W.; Leary, Cynthia B.; Lu, Wei-Ping; Luther, Kylie; Patt, William C.; Petty, Max D.; Romero, Yeni K.; Stanley, Forrest A.; Stoltz, Kristen L.; Tanner, Daniel C.; Yang, Sihyung; Zhan, Yu; Le Bourdonnec, Bertrand; Flynn, Daniel L.
DP-9149, an investigational small molecule modulator of the Integrated Stress Response kinase GCN2, pre-clinically causes solid tumor growth inhibition as a single agent and regression in combination with standard of care agents
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Al-Ani, Gada; Groer, Qi; Elliott, Kristin M.; Rudeen, Aaron J.; Kearney, Patrick C.; Zwicker, Jeffery D.; Ahn, Yu Mi; Bulfer, Stacie L.; Heiniger, Cale L.; Hood, Molly M.; Javid, Salim; Large, Joshua W.; Petty, Max D.; Stoltz, Kristen L.; Le Bourdonnec, Bertrand; Smith, Bryan D.; Flynn, Daniel L.
DP-9024, an investigational small molecule modulator of the Integrated Stress Response kinase PERK, causes B-cell cancer growth inhibition as single agent and in combination with standard-of-care agents
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Al-Ani, Gada; Groer, Qi; Rudeen, Aaron J.; Elliott, Kristin M.; Kearney, Patrick C.; Zwicker, Jeffery D.; Ahn, Yu Mi; Bulfer, Stacie L.; Heiniger, Cale L.; Hood, Molly M.; Javed, Salim; Large, Joshua W.; Petty, Max D.; Stoltz, Kristen L.; Le Bourdonnec, Bertrand; Smith, Bryan D.; Flynn, Daniel L.

研究方向

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B
Bryan D. Smith
H 指数:22论文数:137被引数:2,304
D
Daniel L. Flynn
H 指数:35论文数:209被引数:4,237
G
Gada Al-Ani
H 指数:6论文数:41被引数:559
S
Stacie L. Bulfer
H 指数:15论文数:56被引数:1,329
B
Bertrand Le Bourdonnec
H 指数:18论文数:84被引数:1,583
K
Kristen L. Stoltz
H 指数:8论文数:36被引数:379
M
Molly M. Hood
H 指数:13论文数:64被引数:1,230
Y
Yu Mi Ahn
H 指数:12论文数:59被引数:1,124
C
Cale L. Heiniger
H 指数:2论文数:14被引数:11
M
Max D. Petty
H 指数:1论文数:12被引数:5