Gary L. Firestone - Publications, H-index & Citations

Gary L. Firestone

University of California System

63H指数

229论文数

1.3W被引数

收录论文 53

发表时间

Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells

BIOCHEMICAL PHARMACOLOGY

IF5.6

2017-03-01

PREAI

Quirit, Jeanne G.; Lavrenov, Sergey N.; Poindexter, Kevin; Xu, Janice; Kyauk, Christine; Durkin, Kathleen A.; Aronchik, Ida; Tomasiak, Thomas; Solomatin, Yaroslav A.; Preobrazhenskaya, Maria N.; Firestone, Gary L.

Cooperative antiproliferative signaling by aspirin and indole-3-carbinol targets microphthalmia-associated transcription factor gene expression and promoter activity in human melanoma cells

CELL BIOLOGY AND TOXICOLOGY

IF5.9

2016-04-07

OAAI

Poindexter, Kevin M.; Matthew, Susanne; Aronchik, Ida; Firestone, Gary L.

Designing a broad-spectrum integrative approach for cancer prevention and treatment 设计用于癌症预防和治疗的广谱综合方法

SEMINARS IN CANCER BIOLOGY

IF15.7

2015-12-01

266

OAAI

Block, Keith I.; Gyllenhaal, Charlotte; Lowe, Leroy; Amedei, Amedeo; Amin, A. R. M. Ruhul; Amin, Amr; Aquilano, Katia; Arbiser, Jack; Arreola, Alexandra; Arzumanyan, Alla; Ashraf, S. Salman; Azmi, Asfar S.; Benencia, Fabian; Bhakta, Dipita; Bilsland, Alan; Bishayeen, Anupam; Blain, Stacy W.; Block, Penny B.; Boosani, Chandra S.; Carey, Thomas E.; Carnero, Amancio; Carotenuto, Marianeve; Casey, Stephanie C.; Chakrabarti, Mrinmay; Chaturvedi, Rupesh; Chen, Georgia Zhuo; Chenx, Helen; Chen, Sophie; Chen, Yi Charlie; Choi, Beom K.; Ciriolo, Maria Rosa; Coley, Helen M.; Collins, Andrew R.; Connell, Marisa; Crawford, Sarah; Curran, Colleen S.; Dabrosin, Charlotta; Damia, Giovanna; Dasgupta, Santanu; DeBerardinis, Ralph J.; Decker, William K.; Dhawan, Punita; Diehl, Anna Mae E.; Dong, Jin-Tang; Dou, Q. Ping; Drew, Janice E.; Elkord, Eyad; El-Rayes, Bassel; Feitelson, Mark A.; Felsher, Dean W.; Ferguson, Lynnette R.; Fimognari, Carmela; Firestone, Gary L.; Frezza, Christian; Fujii, Hiromasa; Fuster, Mark M.; Generali, Daniele; Georgakilas, Alexandros G.; Gieseler, Frank; Gilbertson, Michael; Green, Michelle F.; Grue, Brendan; Guha, Gunjan; Halicka, Dorota; Helferich, William G.; Heneberg, Petr; Hentosh, Patricia; Hirschey, Matthew D.; Hofseth, Lorne J.; Holcombe, Randall F.; Honoki, Kanya; Hsu, Hsue-Yin; Huang, Gloria S.; Jensen, Lasse D.; Jiang, Wen G.; Jones, Lee W.; Karpowicz, Phillip A.; Keith, W. Nicol; Kerkar, Sid P.; Khan, Gazala N.; Khatami, Mahin; Ko, Young H.; Kucuk, Omer; Kulathinal, Rob J.; Kumar, Nagi B.; Kwon, Byoung S.; Le, Anne; Lea, Michael A.; Lee, Ho-Young; Lichtor, Terry; Lin, Liang-Tzung; Locasale, Jason W.; Lokeshwar, Bal L.; Longo, Valter D.; Lyssiotis, Costas A.; MacKenzie, Karen L.; Malhotra, Meenakshi; Marino, Maria; Martinez-Chantar, Maria L.; Matheu, Ander; Maxwell, Christopher; McDonnell, Eoin; Meeker, Alan K.; Mehrmohamadi, Mahya; Mehta, Kapil; Michelotti, Gregory A.; Mohammad, Ramzi M.; Mohammed, Sulma I.; Morre, D. James; Muqbil, Irfana; Muralidhar, Vinayak; Murphy, Michael P.; Nagaraju, Ganji Purnachandra; Nahta, Rita; Niccolai, Elena; Nowsheen, Somaira; Panis, Carolina; Pantano, Francesco; Parslow, Virginia R.; Pawelec, Graham; Pedersen, Peter L.; Poore, Brad; Poudyal, Deepak; Prakash, Satya; Prince, Mark; Raffaghello, Lizzia; Rathmell, Jeffrey C.; Rathmell, W. Kimryn; Ray, Swapan K.; Reichrath, Joerg; Rezazadeh, Sarallah; Ribatti, Domenico; Ricciardiello, Luigi; Robey, R. Brooks; Rodier, Francis; Rupasinghe, H. P. Vasantha; Russo, Gian Luigi; Ryan, Elizabeth P.; Samadi, Abbas K.; Sanchez-Garcia, Isidro; Sanders, Andrew J.; Santini, Daniele; Sarkar, Malancha; Sasada, Tetsuro; Saxena, Neeraj K.; Shackelford, Rodney E.; Kumara, H. M. C. Shantha; Sharma, Dipali; Shin, Dong M.; Sidransky, David; Siegelin, Markus David; Signori, Emanuela; Singh, Neetu; Sivanand, Sharanya; Sliva, Daniel; Smythe, Carl; Spagnuolo, Carmela; Stafforini, Diana M.; Stagg, John; Subbarayan, Pochi R.; Sundin, Tabetha; Talib, Wamidh H.; Thompson, Sarah K.; Tran, Phuoc T.; Ungefroren, Hendrik; Vander Heiden, Matthew G.; Venkateswaran, Vasundara; Vinay, Dass S.; Vlachostergios, Panagiotis J.; Wang, Zongwei; Wellendx, Kathryn E.; Whelan, Richard L.; Yang, Eddy S.; Yang, Huanjie; Yang, Xujuan; Yaswen, Paul; Yedjou, Clement; Yin, Xin; Zhu, Jiyue; Zollo, Massimo

Therapeutic targeting of replicative immortality 复制性永生的治疗目标

SEMINARS IN CANCER BIOLOGY

IF15.7

2015-12-01

OAAI

Yaswen, Paul; MacKenzie, Karen L.; Keith, W. Nicol; Hentosh, Patricia; Rodier, Francis; Zhu, Jiyue; Firestone, Gary L.; Matheu, Ander; Carnero, Amancio; Bilsland, Alan; Sundin, Tabetha; Honoki, Kanya; Fujii, Hiromasa; Georgakilas, Alexandros G.; Amedei, Amedeo; Amin, Amr; Helferich, Bill; Boosani, Chandra S.; Guha, Gunjan; Ciriolo, Maria Rosa; Chen, Sophie; Mohammed, Sulma I.; Azmi, Asfar S.; Bhakta, Dipita; Halicka, Dorota; Niccolai, Elena; Aquilano, Katia; Ashraf, S. Salman; Nowsheen, Somaira; Yang, Xujuan

Phytochemical regulation of the tumor suppressive microRNA, miR-34a, by p53-dependent and independent responses in human breast cancer cells

MOLECULAR CARCINOGENESIS

IF3.2

2015-03-19

OAAI

Hargraves, Kris G.; He, Lin; Firestone, Gary L.

The Antiproliferative Response of Indole-3-Carbinol in Human Melanoma Cells Is Triggered by an Interaction with NEDD4-1 and Disruption of Wild-Type PTEN Degradation

MOLECULAR CANCER RESEARCH

IF4.7

2014-11-13

OAAI

Aronchik, Ida; Kundu, Aishwarya; Quirit, Jeanne G.; Firestone, Gary L.

BZL101, a phytochemical extract from the Scutellaria barbata plant, disrupts proliferation of human breast and prostate cancer cells through distinct mechanisms dependent on the cancer cell phenotype

CANCER BIOLOGY & THERAPY

IF4.6

2014-10-27

OAAI

Marconett, Crystal N.; Morgenstern, Travis J.; San Roman, Adrianna K.; Sundar, Shyam N.; Singhal, Ankur K.; Firestone, Gary L.

3,3′-Diindolylmethane rapidly and selectively inhibits hepatocyte growth factor/c-Met signaling in breast cancer cells

JOURNAL OF NUTRITIONAL BIOCHEMISTRY

IF4.9

2013-11-01

OAAI

Nicastro, Holly L.; Firestone, Gary L.; Bjeldanes, Leonard F.

Indole-3-Carbinol disrupts Estrogen Receptor-alpha dependent expression of Insulin-like Growth Factor-1 Receptor and Insulin Receptor Substrate-1 and proliferation of human breast cancer cells

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2012-11-01

OAAI

Marconett, Crystal N.; Singhal, Ankur K.; Sundar, Shyam N.; Firestone, Gary L.

Target Protein Interactions of Indole-3-Carbinol and the Highly Potent Derivative 1-Benzyl-I3C With the C-Terminal Domain of Human Elastase Uncouples Cell Cycle Arrest From Apoptotic Signaling

MOLECULAR CARCINOGENESIS

IF3.2

2011-10-19

PREAI

Aronchik, Ida; Chen, Tony; Durkin, Kathleen A.; Horwitz, Marshall S.; Preobrazhenskaya, Maria N.; Bjeldanes, Leonard F.; Firestone, Gary L.

Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells

CARCINOGENESIS

IF2.9

2011-06-21

OAAI

Marconett, Crystal N.; Sundar, Shyam N.; Tseng, Min; Tin, Antony S.; Tran, Kalvin Q.; Mahuron, Kelly M.; Bjeldanes, Leonard F.; Firestone, Gary L.

Direct Inhibition of Elastase Activity by Indole-3-Carbinol Triggers a CD40-TRAF Regulatory Cascade That Disrupts NF-κB Transcriptional Activity in Human Breast Cancer Cells

CANCER RESEARCH

IF16.6

2010-06-14

OAAI

Aronchik, Ida; Bjeldanes, Leonard F.; Firestone, Gary L.

Indole-3-Carbinol Triggers Aryl Hydrocarbon Receptor-dependent Estrogen Receptor (ER)α Protein Degradation in Breast Cancer Cells Disrupting an ERα-GATA3 Transcriptional Cross-Regulatory Loop

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2010-04-01

OAAI

Marconett, Crystal N.; Sundar, Shyam N.; Poindexter, Kevin M.; Stueve, Theresa R.; Bjeldanes, Leonard F.; Firestone, Gary L.

Selective Activation of Estrogen Receptor-β Target Genes by 3,3′-Diindolylmethane

ENDOCRINOLOGY

IF3.3

2010-02-16

OAAI

Vivar, Omar I.; Saunier, Elise F.; Leitman, Dale C.; Firestone, Gary L.; Bjeldanes, Leonard F.

3,3′-Diindolylmethane induces a G1 arrest in human prostate cancer cells irrespective of androgen receptor and p53 status

BIOCHEMICAL PHARMACOLOGY

IF5.6

2009-09-01

OAAI

Vivar, Omar I.; Lin, Chia-Lei; Firestone, Gary L.; Bjeldanes, Leonard F.

Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2009-03-16

OAAI

Brew, Christine T.; Aronchik, Ida; Kosco, Karena; McCammon, Jasmine; Bjeldanes, Leonard F.; Firestone, Gary L.

Cell type- and estrogen receptor-subtype specific regulation of selective estrogen receptor modulator regulatory elements 选择性雌激素受体调节剂调节元件的细胞类型和雌激素受体亚型特异性调节

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2009-02-01

OAAI

Ball, Lonnele J.; Levy, Nitzan; Zhao, Xiaoyue; Griffin, Chandi; Tagliaferri, Mary; Cohen, Isaac; Ricke, William A.; Speed, Terence P.; Firestone, Gary L.; Leitman, Dale C.

Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expression

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2009-01-01

143

OAAI

Willoughby, Jamin A., Sr.; Sundar, Shyam N.; Cheung, Mark; Tin, Antony S.; Modiano, Jaime; Firestone, Gary L.

The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2008-12-16

OAAI