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G

Glenn S. Belinsky

Yale University

H指数:20

被引数:1,312

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Refining Mouse Models of Gaucher Disease: Advancing Mechanistic Insights, Biomarker Discovery, and Therapeutic Strategies

优化高雪氏病小鼠模型：推进机制洞察、生物标志物发现和治疗策略

International Journal of Molecular Sciences

IF4.9

2026-03-040

OAAI

Modeling bone marrow microenvironment and hematopoietic dysregulation in Gaucher disease through VavCre mediated Gba deletion

通过VavCre介导的Gba基因敲除，对戈谢病中骨髓微环境和造血功能紊乱进行建模

HUMAN MOLECULAR GENETICS

IF3.2

2025-04-080

OA

Molecular cell atlas of the brain in neuronopathic Gaucher disease

MOLECULAR GENETICS AND METABOLISM

IF3.5

2025-02-010

PRE

VavCre mediated conditional deletion of Gba in mice recapitulates human Gaucher disease type 1, a platform to investigate the role of myeloid cells and altered hematopoiesis

MOLECULAR GENETICS AND METABOLISM

IF3.5

2024-02-010

PRE

Osteonecrosis in Gaucher disease in the era of multiple therapies: Biomarker set for risk stratification from a tertiary referral center

IF0

2023-05-303

OA

Single cell resolution of neurodegeneration in Gaucher disease

MOLECULAR GENETICS AND METABOLISM

IF3.5

2023-02-010

PRE

Osteonecrosis in the era of Gaucher disease therapies

MOLECULAR GENETICS AND METABOLISM

IF3.5

2023-02-010

PRE

Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy

IF0

2022-08-1628

OA

Delineating the role of myeloid cells and brain microglia in Gaucher disease

MOLECULAR GENETICS AND METABOLISM

IF3.5

2020-02-010

PREAI

Pigment Epithelium-derived Factor (PEDF) Blocks Wnt3a Protein-induced Autophagy in Pancreatic Intraepithelial Neoplasms

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-10-0115

OAAI

Pigment epithelium-derived factor restoration increases bone mass and improves bone plasticity in a model of osteogenesis imperfecta type VI via Wnt3a blockade

IF4.2

2016-04-2830

OAAI

Connexin hemichannels contribute to spontaneous electrical activity in the human fetal cortex

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-09-0252

OAAI

Pharmacological inhibition of Mdm2 triggers growth arrest and promotes DNA breakage in mouse colon tumors and human colon cancer cells

Mdm2的药理学抑制触发小鼠结肠肿瘤和人结肠癌细胞的生长停滞并促进DNA断裂

MOLECULAR CARCINOGENESIS

IF3.2

2011-05-0638

OAAI

cPLA2 Is Protective Against COX Inhibitor-Induced Intestinal Damage

TOXICOLOGICAL SCIENCES

IF4.1

2010-06-1823

OAAI

DNA damage response to the Mdm2 inhibitor Nutlin-3

BIOCHEMICAL PHARMACOLOGY

IF5.6

2010-02-0163

OAAI

Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis

CANCER RESEARCH

IF16.6

2008-05-01175

PREAI

The contribution of methotrexate exposure and host factors on transcriptional variance in human liver

TOXICOLOGICAL SCIENCES

IF4.1

2007-03-3015

OAAI

Expression of secretory phospholipase A2 in colon tumor cells potentiates tumor growth

MOLECULAR CARCINOGENESIS

IF3.2

2006-11-0742

PREAI

Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors

BIOCHEMICAL PHARMACOLOGY

IF5.6

2006-10-0114

PREAI

Epigenetic alterations in RASSF1A in human aberrant crypt foci

IF2.9

2006-03-0234

OAAI