Börje Darpö - Publications, H-index & Citations

Börje Darpö

newcastle university - uk

33H指数

197论文数

4.2K被引数

收录论文 14

发表时间

Thorough QT Study on the Effect of Therapeutic and Supratherapeutic Dosing of Givinostat in Healthy Volunteers 吉文司他特治疗剂量和超治疗剂量对健康受试者QT间期影响的研究

Clinical Pharmacology in Drug Development

IF1.8

2026-03-22

PREAI

Mercuri, Eugenio; Byrne, Barry; Willis, Tracey; Bourke, John; Bettica, Paolo; Cazzaniga, Sara; Xue, Hongqi; Darpo, Borje

Evaluation of Rusfertide, a Hepcidin Mimetic, on Cardiac Repolarization: A Randomized, Placebo- and Positive-Controlled Crossover Thorough QT Study in Healthy Participants Rusfertide（一种肝细胞素模拟物）对心脏复极化的评估：一项在健康受试者中进行的随机、安慰剂和阳性药物对照交叉 thorough QT 研究

Clinical Therapeutics

IF3.6

2025-09-30

OAAI

Nishit B. Modi; Phillip Dinh; Hongqi Xue; Borje Darpo

Fast and accurate prediction of drug induced proarrhythmic risk with sex specific cardiac emulators

NPJ DIGITAL MEDICINE

IF15.1

2024-12-26

OAAI

Dominguez-Gomez, Paula; Zingaro, Alberto; Baldo-Canut, Laura; Balzotti, Caterina; Darpo, Borje; Morton, Christopher; Vazquez, Mariano; Aguado-Sierra, Jazmin

Concentration-QTc analysis of soticlestat in healthy adults: An alternative to a thorough QT study

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2024-09-23

OAAI

Yin, Wei; Dote, Nobuhito; Fukase, Hiroyuki; Imazaki, Manami; Shimizu, Kohei; Takeda, Shinichi; Darpo, Borje; Xue, Hongqi; Asgharnejad, Mahnaz

A phase I thorough QT/QTc study evaluating therapeutic and supratherapeutic doses of avacopan in healthy participants

CTS-CLINICAL AND TRANSLATIONAL SCIENCE

IF2.8

2024-07-07

OAAI

Miao, Shichang; Staehr, Peter; Tai, Ezra; Darpo, Borje; Xue, Hongqi; Armas, Danielle; Webster, Kenneth; Oberoi, Rajneet K.

Discovery and Model-Informed Drug Development of a Controlled-Release Formulation of Nonracemic Amisulpride that Reduces Plasma Exposure but Achieves Pharmacodynamic Bioequivalence in the Brain

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2024-05-31

PREAI

Hopkins, Seth C.; Toongsuwan, Siriporn; Corriveau, Taryn J.; Watanabe, Takao; Tsushima, Yuki; Asada, Takumi; Lew, Robert; Shi, Lei; Zann, Vanessa; Snowden, Thomas J.; van Der Graaf, Piet H.; Darpo, Borje; Searle, Graham E.; Rabiner, Eugenii A.; Wilding, Ian; Szabo, Steven T.; Galluppi, Gerald R.; Koblan, Kenneth S.

Relacorilant, a Selective Glucocorticoid Receptor Modulator in Development for the Treatment of Patients With Cushing Syndrome, Does Not Cause Prolongation of the Cardiac QT Interval

ENDOCRINE PRACTICE

IF4.6

2024-01-01

OAAI

Donegan, Diane M.; Pivonello, Rosario; Stigliano, Antonio; Lardo, Pina; Kearney, Tara; Mezosi, Emese; Ghigo, Ezio; Giordano, Roberta; Mariash, Cary N.; Feelders, Richard A.; Donaldson, Kirsteen; Darpo, Borje; Xue, Hongqi; Custodio, Joseph M.; Hand, Austin L.; Moraitis, Andreas G.

Mortality and ventricular arrhythmias in patients on d,l-sotalol for rhythm control of atrial fibrillation: A nationwide cohort study

HEART RHYTHM

IF5.7

2023-11-01

OAAI

Lenhoff, Hanna; Peterson, Hans Jarnbert; Darpo, Borje; Tornvall, Per; Frick, Mats

A randomized, single-dose, crossover study of the effects of ulotaront on electrocardiogram intervals in subjects with schizophrenia

CTS-CLINICAL AND TRANSLATIONAL SCIENCE

IF2.8

2023-03-28

OAAI

Tsukada, Hironobu; Milanovic, Snezana M.; Darpo, Borje; Xue, Hongqi; Xiong, Kuangnan; Tripp, Emily; Lennek, Lisa; Worden, MaryAlice; Hopkins, Seth C.; Galluppi, Gerald R.

Pridopidine Does Not Significantly Prolong the QTc Interval at the Clinically Relevant Therapeutic Dose 普利多匹定在临床相关治疗剂量下不会显着延长QTc间隔

NEUROLOGY AND THERAPY

IF4.8

2023-02-22

OAAI

Darpo, Borje; Geva, Michal; Ferber, Georg; Goldberg, Yigal Paul; Cruz-Herranz, Andres; Mehra, Munish; Kovacs, Richard; Hayden, Michael R.

Omecamtiv mecarbil does not prolong QTc intervals at therapeutic concentrations

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2021-07-16

OAAI

Trivedi, Ashit; Hsu, Cheng-Pang; Jafarinasabian, Pegah; Terminello, Bianca; Zhang, Hanze; Flach, Stephen; Israel, Samuel; Brooks, Ashley; Xue, Hongqi; Darpo, Borje; Abbasi, Siddique; Dutta, Sandeep; Lee, Edward

The effect of the glucosylceramide synthase inhibitor lucerastat on cardiac repolarization: results from a thorough QT study in healthy subjects

ORPHANET JOURNAL OF RARE DISEASES

IF3.5

2020-10-27

OAAI

Mueller, Markus S.; Sidharta, Patricia N.; Voors-Pette, Christine; Darpo, Borje; Xue, Hongqi; Dingemanse, Jasper

Potential strategy for assessing QT/QTc interval for drugs that produce rapid changes in heart rate: Electrocardiographic assessment of the effects of intravenous remimazolam on cardiac repolarization

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2020-03-23

OAAI

Kleiman, Robert B.; Darpo, Borje; Thorn, Michael; Stoehr, Thomas; Schippers, Frank

Exenatide at therapeutic and supratherapeutic concentrations does not prolong the QTc interval in healthy subjects

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2013-03-15

OAAI

Darpo, Borje; Sager, Philip; MacConell, Leigh; Cirincione, Brenda; Mitchell, Malcolm; Han, Jenny; Huang, Wenying; Malloy, Jaret; Schulteis, Christine; Shen, Larry; Porter, Lisa

研究方向